Search filters

List of works by Jeremy Smedley

A macaque model of HIV-1 infection

scholarly article

Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapy

scientific article

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

scientific article

Defining early SIV replication and dissemination dynamics following vaginal transmission

article

Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection

scientific article

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

scientific article published in Nature Communications

Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques

scientific article

Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

scientific article published on 11 March 2021

Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy

scientific article published on 28 December 2015

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies.

scientific article

Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection

scientific article

Ferumoxytol as an intraprostatic MR contrast agent for lymph node mapping of the prostate: a feasibility study in non-human primates.

scientific article published on 26 May 2015

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV

scientific article published on 12 July 2018

Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides

scientific article published on 16 June 2015

HIV-1-induced AIDS in monkeys

scientific article

Identification of novel simian endogenous retroviruses that are indistinguishable from simian retrovirus (SRV) on current SRV diagnostic assays

scientific article

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

scientific article published on 24 November 2020

Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates

scientific article published on 06 May 2019

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

scientific article published on 2 May 2017

Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

scientific article

Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity

scientific article published in 2022

Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques

scientific article published on 10 May 2021

Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events

scientific article

Mucosal T helper 17 and T regulatory cell homeostasis correlates with acute SIV viremia and responsiveness to antiretroviral therapy in macaques

scientific article published on 02 January 2019

Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates

scientific article published on 29 May 2020

Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model

scientific article (publication date: 2013)

Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection

scientific article published on 19 October 2012

Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques

scientific article published on 11 January 2012

Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques

scientific article

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins

scientific article

Short Communication: Comparative Evaluation of Coformulated Injectable Combination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques

scientific article published on 6 July 2015

Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology

scientific article published on 28 August 2019

Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys

scientific article

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy

scientific article

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation.

scientific article

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

scientific article published on 12 March 2020

Therapeutic neutralizing monoclonal antibody administration protects against lethal yellow fever virus infection

scientific article published in 2023

Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission

scientific article (publication date: 2014)

Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates

scientific article

Transmission of MDR MRSA between primates, their environment and personnel at a United States primate centre

scientific article

Vaccine-induced myeloid cell population dampens protective immunity to SIV

scientific article

Paulina is supported by:

About Paulina

Help