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List of works by Knut Woltjen

An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development

scientific article published on 16 March 2016

An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming

scientific article

Beta-cell replacement strategies for diabetes

scientific article

Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

scientific article published on January 2013

Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas

scientific article published on 05 September 2019

Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch.

scientific article published on 19 May 2017

Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior

scientific article published on 05 January 2017

Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells.

scientific article published in January 2016

Efficient TALEN construction and evaluation methods for human cell and animal applications.

scientific article published on 6 February 2013

Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro

scientific article (publication date: 2013)

Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives.

scientific article published on 17 December 2015

Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells.

scientific article published in October 2017

Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming

scientific article

Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations

scientific article published on 24 October 2019

Highly efficient site-specific transgenesis in cancer cell lines

scientific article published on 11 December 2012

Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency.

scientific article published in May 2017

Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells ⬇️

scientific article published on January 10, 2013

In vivo reprogramming drives Kras-induced cancer development.

scientific article published on 25 May 2018

Induced pluripotent stem cell lines derived from equine fibroblasts

scientific article published on September 2011

Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons

scientific article published on 30 May 2015

KLF4 N-terminal variance modulates induced reprogramming to pluripotency

scientific article

Microhomology-assisted scarless genome editing in human iPSCs.

scientific article published on 5 March 2018

Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes

scientific article published on 10 July 2015

New strategies to generate induced pluripotent stem cells.

scientific article published on October 2009

Nuclease-mediated genome editing: At the front-line of functional genomics technology

scientific article published on 05 January 2014

Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement

scientific article

PhiC31 integrase facilitates genetic approaches combining multiple recombinases

scientific article published on 23 December 2010

Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation

scientific article

Preview. Inhibition of Tgf-beta signaling improves mouse fibroblast reprogramming

scientific article published on 01 November 2009

Recapitulating the human segmentation clock with pluripotent stem cells

scientific article published on 01 April 2020

Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara.

scientific article published on 29 March 2016

Reprogramming Roadblocks Are System Dependent

scientific article

Retro-recombination screening of a mouse embryonic stem cell genomic library.

scientific article

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

scientific article published on 16 July 2015

SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier

scientific article

Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs.

scientific article published on 11 April 2018

Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation

scientific article published on 08 June 2020

Synthetic lateral inhibition governs cell-type bifurcation with robust ratios.

scientific article published on 5 February 2015

The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.

scientific article

The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse.

scientific article published in July 2015

Transgene-free production of pluripotent stem cells using piggyBac transposons

scientific article

Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway.

scientific article published on November 2013

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

scientific article

iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease.

scientific article published in November 2017

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

scientific article (publication date: 9 April 2009)

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