List of works - Dimitra Dafou

3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells

scientific article

A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro.

scientific article published in July 2004

A short purification process for quantitative isolation of PrPSc from naturally occurring and experimental transmissible spongiform encephalopathies.

scientific article

Analysis of Creutzfeldt-Jakob disease infectious fractions by gel permeation chromatography and sedimentation field flow fractionation.

scientific article published in December 1992

Cancer stem cells and epithelial ovarian cancer

scientific article

Caprine PrP variants harboring Asp-146, His-154 and Gln-211 alleles display reduced convertibility upon interaction with pathogenic murine prion protein in scrapie infected cells

scientific article published on 18 August 2016

Characterization of the murine BSE infectious agent

scientific article

Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells.

scientific article

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

scientific article

De novo mutations in MLL cause Wiedemann-Steiner syndrome

scientific article

De novo mutations of the gene encoding the histone acetyltransferase KAT6B cause Genitopatellar syndrome

scientific article published on 19 January 2012

Down-regulation of the Tumor Suppressor CYLD Enhances the Transformed Phenotype of Human Breast Cancer Cells.

scientific article

Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and golgi organization and is associated with protein secretion pathways critical in bone development

scientific article

EU-approved rapid tests might underestimate bovine spongiform encephalopathy infection in goats.

scientific article published on January 2017

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

scientific article published in October 2007

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

scientific article published on 6 March 2009

Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies

scientific article

Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma.

scientific article published on 28 July 2016

Hidradenitis suppurativa: haploinsufficiency of gamma-secretase components does not affect gamma-secretase enzyme activity in vitro

scientific article published in April 2016

Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.

scientific article

In vitro three-dimensional modelling of human ovarian surface epithelial cells.

scientific article published on 24 April 2009

Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin

scientific article published on 26 July 2016

Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.

scientific article

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.

scientific article

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

article by Pia Ostergaard et al published 4 September 2011 in Nature Genetics

Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome

scientific article

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

scientific article

Mutations in the γ-Secretase Genes NCSTN , PSENEN , and PSEN1 Underlie Rare Forms of Hidradenitis Suppurativa (Acne Inversa)

article

Non-competitive inhibition of ornithine decarboxylase by a phosphopeptide and phosphoamino acids.

scientific article published in December 1986

Novel SPG11 mutations in Asian kindreds and disruption of spatacsin function in the zebrafish

scientific article

Novel mutation of the PRNP gene of a clinical CJD case

scientific article

Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats.

scientific article

Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer

scientific article

Prion protein gene polymorphisms in natural goat scrapie

scientific article

Profiling signatures of ovarian cancer tumour suppression using 2D-DIGE and 2D-LC-MS/MS with tandem mass tagging.

scientific article

Purification and properties of ornithine decarboxylase from Tetrahymena pyriformis.

scientific article

RNA editing alterations define manifestation of prion diseases

scientific article published on 06 September 2019

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

scientific article published on 22 January 2018

TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult

scientific article published on 6 December 2010

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

scientific article

Three-dimensional in vitro cell biology models of ovarian and endometrial cancer.

scientific article

List of works by Dimitra Dafou

3D In vitro model of a functional epidermal permeability barrier from human embryonic stem cells and induced pluripotent stem cells

A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro.

A short purification process for quantitative isolation of PrPSc from naturally occurring and experimental transmissible spongiform encephalopathies.

Analysis of Creutzfeldt-Jakob disease infectious fractions by gel permeation chromatography and sedimentation field flow fractionation.

Cancer stem cells and epithelial ovarian cancer

Caprine PrP variants harboring Asp-146, His-154 and Gln-211 alleles display reduced convertibility upon interaction with pathogenic murine prion protein in scrapie infected cells

Characterization of the murine BSE infectious agent

Chromosomes 6 and 18 induce neoplastic suppression in epithelial ovarian cancer cells.

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

De novo mutations in MLL cause Wiedemann-Steiner syndrome

De novo mutations of the gene encoding the histone acetyltransferase KAT6B cause Genitopatellar syndrome

Down-regulation of the Tumor Suppressor CYLD Enhances the Transformed Phenotype of Human Breast Cancer Cells.

Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and golgi organization and is associated with protein secretion pathways critical in bone development

EU-approved rapid tests might underestimate bovine spongiform encephalopathy infection in goats.

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival

Gain-of-function mutations of ARHGAP31, a Cdc42/Rac1 GTPase regulator, cause syndromic cutis aplasia and limb anomalies

Hepatitis C virus suppresses Hepatocyte Nuclear Factor 4 alpha, a key regulator of hepatocellular carcinoma.

Hidradenitis suppurativa: haploinsufficiency of gamma-secretase components does not affect gamma-secretase enzyme activity in vitro

Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression.

In vitro three-dimensional modelling of human ovarian surface epithelial cells.

Induced Pluripotent Stem Cell Differentiation and Three-Dimensional Tissue Formation Attenuate Clonal Epigenetic Differences in Trichohyalin

Microcell-mediated chromosome transfer identifies EPB41L3 as a functional suppressor of epithelial ovarian cancers.

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers.

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

Mutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndrome

Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

Mutations in the γ-Secretase Genes NCSTN , PSENEN , and PSEN1 Underlie Rare Forms of Hidradenitis Suppurativa (Acne Inversa)

Non-competitive inhibition of ornithine decarboxylase by a phosphopeptide and phosphoamino acids.

Novel SPG11 mutations in Asian kindreds and disruption of spatacsin function in the zebrafish

Novel mutation of the PRNP gene of a clinical CJD case

Perspectives of a scrapie resistance breeding scheme targeting Q211, S146 and K222 caprine PRNP alleles in Greek goats.

Pregnancy-associated plasma protein A regulates mitosis and is epigenetically silenced in breast cancer

Prion protein gene polymorphisms in natural goat scrapie

Profiling signatures of ovarian cancer tumour suppression using 2D-DIGE and 2D-LC-MS/MS with tandem mass tagging.

Purification and properties of ornithine decarboxylase from Tetrahymena pyriformis.

RNA editing alterations define manifestation of prion diseases

Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.

TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

Three-dimensional in vitro cell biology models of ovarian and endometrial cancer.