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List of works by Juan Carlos Acosta

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

scientific article

A role for CXCR2 in senescence, but what about in cancer?

scientific article published on 10 March 2009

Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells.

scientific article published on September 2003

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

scientific article

Chemokine signaling via the CXCR2 receptor reinforces senescence

scientific article

Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability

scientific article

Control of senescence by CXCR2 and its ligands

scientific article published on 13 October 2008

Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence

scientific article published on 16 December 2021

Detecting the Senescence-Associated Secretory Phenotype (SASP) by High Content Microscopy Analysis

scientific article

High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle

scientific article

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

scientific article

Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?

scientific article published on 10 April 2009

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

scientific article published on 31 May 2019

Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence

Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes

scientific article (publication date: 30 June 2005)

MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide

scientific article

MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.

scientific article published on April 2011

Measuring the Inflammasome in Oncogene-Induced Senescence

scientific article published in January 2019

Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest

scientific article published on 6 October 2008

Nuclear pore density controls heterochromatin reorganization during senescence

PHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359

scientific article published on 01 July 2018

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.

scientific article published on 9 March 2018

Premature senescence in cells from patients with autosomal recessive hypercholesterolemia (ARH): evidence for a role for ARH in mitosis.

scientific article published on 21 July 2011

SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.

scientific article

Senescence impairs successful reprogramming to pluripotent stem cells

scientific article

Senescence: a new weapon for cancer therapy

scientific article published on 13 January 2012

Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage

scientific article published on 7 December 2022

Suppression of autophagy impedes glioblastoma development and induces senescence

scientific article published on 15 June 2016

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

scientific article published on 05 June 2019

Unbiased Characterization of the Senescence-Associated Secretome Using SILAC-Based Quantitative Proteomics

scientific article published on 01 January 2013

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

scientific article

p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.

scientific article published on 3 March 2005

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