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List of works by Ulla Mandel

A glycogene mutation map for discovery of diseases of glycosylation

scientific article

A novel monoclonal antibody to a defined peptide epitope in MUC16.

scientific article published on 22 July 2015

A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody

scientific article published on 01 April 2019

A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution

A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation

scientific article published on 01 August 2019

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity

scientific article published on 10 August 2012

Altered Expression of Epithelial Cell Surface Glycoconjugates and Intermediate Filaments at the Margins of Mucosal Wounds

scientific article published on 01 October 1998

An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells

scientific article published on 18 June 2019

Asthma induction in mice leads to appearance of alpha2-3- and alpha2-6-linked sialic acid residues in respiratory goblet-like cells

scientific article

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

scientific article published on 7 May 2013

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

scientific article published on 04 November 2020

Characterization of binding epitopes of CA125 monoclonal antibodies.

scientific article published on 4 June 2014

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

scientific article published on 5 October 2005

Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family ⬇️

scientific article published on December 18, 2011

De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium. ⬇️

scientific article published on 29 November 2017

Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in Sjogren's syndrome patients.

scientific article

Detection of glyco-mucin profiles improves specificity of MUC16 and MUC1 biomarkers in ovarian serous tumours.

scientific article published on 22 October 2014

Display of the human mucinome with defined O-glycans by gene engineered cells

scientific article

Egghead and brainiac are essential for glycosphingolipid biosynthesis in vivo.

scientific article published on 15 December 2004

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

scientific article published on June 2016

Engineering mammalian mucin-type O-glycosylation in plants.

scientific article published on 14 February 2012

Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics

scientific article published on 30 April 2019

Expression of Mucin-1 in multiple myeloma and its precursors: correlation with glycosylation and subcellular localization

scientific article published on 21 January 2014

Expression of the -Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

scholarly article by Marie B Nygaard published in September 2018

GLYCAN-DIRECTED CAR-T CELLS.

scientific article published on 23 January 2018

Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16.

scientific article

Generation of Monoclonal Antibodies to Native Active Human Glycosyltransferases ⬇️

scientific article published on January 1, 2013

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

scientific article published on July 2012

Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process

scientific article

Loss of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 and reduced O-glycosylation in colon carcinoma cells selected for hepatic metastasis

scientific article

Loss of a novel mucin-like epithelial glycoprotein in oral and cervical squamous cell carcinomas

scientific article published on 01 February 1997

Microarray Glycoprofiling of CA125 improves differential diagnosis of ovarian cancer.

scientific article published on 19 February 2013

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines

scientific article published on 9 October 2011

Mucins and Truncated -Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours

scientific article published on 13 July 2018

Mucins and associated glycan signatures in colon adenoma-carcinoma sequence: Prospective pathological implication(s) for early diagnosis of colon cancer.

scientific article published on 16 February 2016

Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell

scientific article published on 01 November 2019

O-linked glycosylation of the mucin domain of the herpes simplex virus type 1-specific glycoprotein gC-1 is temporally regulated in a seed-and-spread manner

scientific article

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

scientific article published on 12 April 2013

Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells

scientific article

Probing the O-glycoproteome of gastric cancer cell lines for biomarker discovery.

scientific article published on 26 March 2015

Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines

scientific article published in Journal of Biological Chemistry

Reduced sulfation of muc5b is linked to xerostomia in patients with Sjögren syndrome.

scientific article

Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

scientific article published on 27 April 2010

ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.

scientific article published in June 2011

Seromic profiling of colorectal cancer patients with novel glycopeptide microarray

scientific article published on 12 January 2011

Simple mucin-type carbohydrate antigens in pleomorphic adenomas.

scientific article

Simple mucin-type carbohydrates in normal and malignant human endometrium

scientific article published on 01 April 1995

Site-specific O-glycosylation on the MUC2 mucin protein inhibits cleavage by the Porphyromonas gingivalis secreted cysteine protease (RgpB).

scientific article published on April 2013

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

scientific article published on 7 May 2015

The Thomsen-Friedenreich (T) simple mucin-type carbohydrate antigen in salivary gland carcinomas

scientific article published on 01 November 1995

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells

scientific article published on 30 April 2019

The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation

scientific article published on 10 January 2007

Toward stable genetic engineering of human O-glycosylation in plants

article

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

scientific article published on 01 September 2007

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