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Authors whose works are in public domain in at least one jurisdiction

List of works by Dmitry A. Gordenin

1-50 of 83 results

Mutational heterogeneity in cancer and the search for new cancer-associated genes

scientific article

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

scientific article published on 14 July 2013

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article

The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

scientific article (publication date: 8 September 2014)

Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions.

scientific article

Hypermutability of homonucleotide runs in mismatch repair and DNA polymerase proofreading yeast mutants.

scientific article published on May 1997

Hypermutation in human cancer genomes: footprints and mechanisms

scientific article

Cadmium is a mutagen that acts by inhibiting mismatch repair.

scientific article published on July 2003

An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers

scientific article

Destabilization of Yeast Micro- and Minisatellite DNA Sequences by Mutations Affecting a Nuclease Involved in Okazaki Fragment Processing (rad27) and DNA Polymerase δ (pol3-t)

scientific article published on May 1, 1998

Inverted DNA repeats: a source of eukaryotic genomic instability

scientific article published on September 1993

The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

scientific article

Repeat expansion--all in a flap?

scientific article published on 01 June 1997

Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick

scientific article (publication date: 17 January 2003)

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

scientific article

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes.

scientific article published on October 1995

The repertoire of mutational signatures in human cancer

scientific article published on 05 February 2020

Break-induced replication is a source of mutation clusters underlying kataegis

scientific article

Flexibility of eukaryotic Okazaki fragment maturation through regulated strand displacement synthesis

scientific article published on 16 October 2008

A novel role in DNA metabolism for the binding of Fen1/Rad27 to PCNA and implications for genetic risk.

scientific article

Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability.

scientific article published on January 2001

Factors Affecting Inverted Repeat Stimulation of Recombination and Deletion in Saccharomyces cerevisiae

scientific article published on April 1, 1998

Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition.

scientific article

Yeast ARMs (DNA at-risk motifs) can reveal sources of genome instability

scientific article published on May 25, 1998

Mutator phenotypes of yeast strains heterozygous for mutations in the MSH2 gene.

scientific article

Conservative repair of a chromosomal double-strand break by single-strand DNA through two steps of annealing.

scientific article

Transposon Tn5 excision in yeast: influence of DNA polymerases alpha, delta, and epsilon and repair genes

scientific article published on May 1, 1992

The multiple biological roles of the 3'-->5' exonuclease of Saccharomyces cerevisiae DNA polymerase delta require switching between the polymerase and exonuclease domains

scientific article

Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes

scientific article

Genome-wide model for the normal eukaryotic DNA replication fork.

scientific article

Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency

scientific article published in November 2017

Clusters of Multiple Mutations: Incidence and Molecular Mechanisms

scientific article

Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis.

scientific article published on 11 February 2008

Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent

scientific article

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

scientific article

Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast.

scientific article

The prevention of repeat-associated deletions in Saccharomyces cerevisiae by mismatch repair depends on size and origin of deletions.

scientific article

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

scientific article

A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast

scientific article published on July 21, 2010

Damage-induced localized hypermutability.

scientific article

The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis

scientific article published on August 26, 2013

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

scientific article published on 01 December 2018

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability

scientific article (publication date: November 1999)

The impact of environmental and endogenous damage on somatic mutation load in human skin fibroblasts

journal article published in 2016

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast.

scientific article published on February 1997

Alkylation base damage is converted into repairable double-strand breaks and complex intermediates in G2 cells lacking AP endonuclease.

scientific article

Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness

scientific article

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

scientific article published on 05 February 2020

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

scientific article published on 02 December 2013

The transition of closely opposed lesions to double-strand breaks during long-patch base excision repair is prevented by the coordinated action of DNA polymerase delta and Rad27/Fen1.

scientific article published on 15 December 2008