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List of works by Iain A McNeish

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article
Rethinking ovarian cancer: recommendations for improving outcomes

scientific article
Paraneoplastic thrombocytosis in ovarian cancer.

scientific article published on February 2012
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.

scientific article published on 28 November 2016
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.

scientific article
Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 12 September 2017
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

scientific article
Interleukin-6 as a therapeutic target in human ovarian cancer

scientific article
Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

scientific article published on 6 June 2017
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck.

scientific article
Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015
Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.

scientific article published on June 2010
Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000.

scientific article published in April 2002
Randomized phase II placebo-controlled trial of maintenance therapy using the oral triple angiokinase inhibitor BIBF 1120 after chemotherapy for relapsed ovarian cancer.

scientific article
Survivin: a protein with dual roles in mitosis and apoptosis

scientific article
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article
Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells

scientific article
Expression of the IAP protein family is dysregulated in pancreatic cancer cells and is important for resistance to chemotherapy

scientific article published on 01 June 2007
Tropism-modification strategies for targeted gene delivery using adenoviral vectors

scientific article
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016
Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes.

scientific article published on March 2004
Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2.

scientific article published on 4 September 2017
Targeted anti-vascular therapies for ovarian cancer: current evidence

scientific article
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article
Gynecologic Cancer InterGroup (GCIG) consensus review for clear cell carcinoma of the ovary

scientific article
Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells

scientific article published on September 24, 2013
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway

scientific article (publication date: 10 June 2003)
A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer.

scientific article published on 18 March 2014
A randomised, placebo-controlled trial of weekly paclitaxel and saracatinib (AZD0530) in platinum-resistant ovarian, fallopian tube or primary peritoneal cancer†.

scientific article published on 28 July 2014
Neoadjuvant Chemotherapy Modulates the Immune Microenvironment in Metastases of Tubo-Ovarian High-Grade Serous Carcinoma.

scientific article published in June 2016
Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.

scientific article published in January 2006
Copy number signatures and mutational processes in ovarian carcinoma

scientific article published on 13 August 2018
Malignant ovarian germ cell tumors: identification of novel prognostic markers and long-term outcome after multimodality treatment

scientific article published on 01 October 2006
In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

scientific article published on 15 April 2009
CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

scientific article published on 16 August 2016
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

scientific article published in Nature Communications
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016
Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.

scientific article
Twenty-five years' clinical experience with placental site trophoblastic tumors.

scientific article
The Initiator Methionine tRNA Drives Secretion of Type II Collagen from Stromal Fibroblasts to Promote Tumor Growth and Angiogenesis

scientific article published on 2 March 2016
The peritoneal tumour microenvironment of high-grade serous ovarian cancer.

scientific article published on 18 April 2012
Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer

scientific article published on August 23, 2010
Polo-like kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancer.

scientific article published on 14 March 2011
Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours.

scientific article
Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis.

scientific article published in October 2008
Paclitaxel-containing high-dose chemotherapy for relapsed or refractory testicular germ cell tumours.

scientific article published on March 2004
Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015
Repeatability of quantitative FDG-PET/CT and contrast-enhanced CT in recurrent ovarian carcinoma: test-retest measurements for tumor FDG uptake, diameter, and volume.

scientific article published on 26 February 2014
Failure of translation of human adenovirus mRNA in murine cancer cells can be partially overcome by L4-100K expression in vitro and in vivo.

scientific article

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