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List of works by Fabian V. Filipp

A Gateway between Omics Data and Systems Biology

scientific article published in November 2013

A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity

scientific article published on 16 February 2021

A network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer.

scientific article published in July 2018

An epigenetic master regulator teams up to become an epioncogene.

scientific article published on 22 March 2017

Automated evaluation of chemical shift perturbation spectra: New approaches to quantitative analysis of receptor-ligand interaction NMR spectra

scientific article

Binding and pKa Modulation of a Polycyclic Substrate Analogue in a Type II Polyketide Acyl Carrier Protein ⬇️

scientific article published on February 22, 2011

Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation

scientific article published on 10 March 2020

CD271 is a molecular switch with divergent roles in melanoma and melanocyte development

article

Cancer metabolism meets systems biology: Pyruvate kinase isoform PKM2 is a metabolic master regulator.

scientific article published on 24 July 2013

Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma

scientific article

Chemoprevention agents for melanoma: a path forward into phase 3 clinical trials

scientific article published on 03 October 2018

Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet

scientific article published on 06 November 2019

Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect

scientific article published on 13 October 2011

Concurrent Targeting of Glutaminolysis and Metabotropic Glutamate Receptor 1 (GRM1) Reduces Glutamate Bioavailability in GRM1+ Melanoma

scientific article published on 15 April 2019

Conformational plasticity of the lipid transfer protein SCP2

scientific article

Crosstalk between epigenetics and metabolism-Yin and Yang of histone demethylases and methyltransferases in cancer.

scientific article

Determinants of conformational dimerization of Mad2 and its inhibition by p31comet

scientific article

Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling

scientific article published on 21 February 2019

EZH2 as a mediator of treatment resistance in melanoma

scientific article

Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis

scientific article published on 14 October 2019

Frontiers in pigment cell and melanoma research

scientific article published on 03 October 2018

Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma.

scientific article published on October 2012

Hypermutation of DPYD Deregulates Pyrimidine Metabolism and Promotes Malignant Progression.

scientific article

Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance

scientific article

Is science killing sport? Gene therapy and its possible abuse in doping

scientific article

Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins

scientific article

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.

scientific article

Metabolic shift in density-dependent stem cell differentiation

scientific article published on 20 October 2017

Opportunities for Artificial Intelligence in Advancing Precision Medicine

scientific article published on 01 December 2019

Precision medicine driven by cancer systems biology

scientific article published on 07 March 2017

Probing lipid- and drug-binding domains with fluorescent dyes

scientific article

Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

scientific article

Refinement of the androgen response element based on ChIP-Seq in androgen-insensitive and androgen-responsive prostate cancer cell lines.

scientific article published on 14 September 2016

Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells ⬇️

scientific article published on March 27, 2012

Reversing the rewiring of cancer

scientific article published on January 2013

Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma

scientific article published on February 2016

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19

scientific article

Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma.

scientific article published on 4 April 2018

Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins.

scientific article published on December 2007

Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes

scientific article

The histone demethylase KDM3A regulates the transcriptional program of the androgen receptor in prostate cancer cells

scientific article

The triennial International Pigment Cell Conference (IPCC)

scientific article

Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain

scientific article

Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα

scientific article published on 5 January 2012

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