List of works - Lee M Wetzler

AIDS vaccine and the private sector

scientific article published on 01 June 1986

An epitope shared by enterobacterial and neisserial porin proteins

scientific article published on 01 August 1998

Analysis of parameters associated with prevention of cellular apoptosis by pathogenic Neisseriae and purified porins.

scientific article published in January 2012

Antibiotics for respiratory tract infections: a comparison of prescribing in an outpatient setting

scientific article published on February 2015

Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia

scientific article

Correction for Massari et al., meningococcal porin PorB prevents cellular apoptosis in a Toll-like receptor 2- and NF-κB-independent manner

scientific article published on August 2015

Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition

scientific article

Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

scientific article published on February 2002

Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria.

scientific article published in November 2005

Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet.

scientific article

Gonococcal porin vaccine evaluation: comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants

scientific article published on September 1, 1992

Human airway epithelial cell responses to Neisseria lactamica and purified porin via Toll-like receptor 2-dependent signaling ⬇️

scientific article published on 11 October 2010

Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia.

scientific article

Immunopotentiating ability of neisserial major outer membrane proteins. Use as an adjuvant for poorly immunogenic substances and potential use in vaccines

scientific article published on 01 August 1994

In vivo and in vitro characterization of the immune stimulating activity of the Neisserial porin PorB

scientific article

Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells

scientific article published on 12 March 2007

Innate immunity and vaccines.

scientific article

Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona Formation

scientific article published on 31 December 2015

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

scientific article published on 21 December 2012

Meningococcal PorB induces a robust and diverse antigen specific T cell response as a vaccine adjuvant

scientific article published on 28 October 2018

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

scientific journal article

Meningococcal porin PorB prevents cellular apoptosis in a toll-like receptor 2- and NF-kappaB-independent manner

scientific article

Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1

scientific article published on 01 June 2005

Neisseria gonorrhoeae porin P1.B induces endosome exocytosis and a redistribution of Lamp1 to the plasma membrane.

scientific article published on November 2002

Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia.

scientific article published on 9 July 2008

Neisseriae internalization by epithelial cells is enhanced by TLR2 stimulation

scientific article

Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis.

scientific article

Neisserial porin-induced dendritic cell activation is MyD88 and TLR2 dependent

scientific article published on 01 March 2005

Serum resistance of Neisseria gonorrhoeae. Does it thwart the inflammatory response and facilitate the transmission of infection?

scientific article

Specific binding to differentially-expressed human CEACAMs determines the outcome of Neisseria gonorrhoeae infections along the female reproductive tract.

scientific article

Studies on the effect of neisserial porins on apoptosis of Mammalian cells.

scientific article

Summary and Recommendations from the National Institute of Allergy and Infectious Diseases (NIAID) Workshop "Gonorrhea Vaccines: the Way Forward".

scientific article published on 22 June 2016

T cell activation by TLRs: a role for TLRs in the adaptive immune response

scientific article published on 04 September 2007

T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections

scientific article published on 01 September 1999

Testing meningococcal vaccines for mitogenicity and superantigenicity.

scientific article

The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant.

scientific article published on 26 December 2007

The Role of TLR2 in Infection and Immunity

scientific article published on 18 April 2012

The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation.

scientific article

The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.

scientific article

The nature of an in vivo anti-capsular polysaccharide response is markedly influenced by the composition and/or architecture of the bacterial subcapsular domain.

scientific article published on 7 December 2011

The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca(2+) transients in infected epithelial cells

scientific article published on 01 December 2005

The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice.

scientific article published on 23 December 2015

The role of B/T costimulatory signals in the immunopotentiating activity of neisserial porin

scientific article published on 01 September 1999

The role of porins in neisserial pathogenesis and immunity.

scientific article

Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production.

scientific article published on 03 March 2017

Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells

article

Toll-like receptor 2-mediated human B cell differentiation

scientific article

Vaccines for gonorrhea: where are we on the curve?

scientific article published on December 1995

List of works by Lee M Wetzler

AIDS vaccine and the private sector

An epitope shared by enterobacterial and neisserial porin proteins

Analysis of parameters associated with prevention of cellular apoptosis by pathogenic Neisseriae and purified porins.

Antibiotics for respiratory tract infections: a comparison of prescribing in an outpatient setting

Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia

Correction for Massari et al., meningococcal porin PorB prevents cellular apoptosis in a Toll-like receptor 2- and NF-κB-independent manner

Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition

Cutting edge: Immune stimulation by neisserial porins is toll-like receptor 2 and MyD88 dependent.

Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria.

Distinct gene signatures in aortic tissue from ApoE-/- mice exposed to pathogens or Western diet.

Gonococcal porin vaccine evaluation: comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants

Human airway epithelial cell responses to Neisseria lactamica and purified porin via Toll-like receptor 2-dependent signaling ⬇️

Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia.

Immunopotentiating ability of neisserial major outer membrane proteins. Use as an adjuvant for poorly immunogenic substances and potential use in vaccines

In vivo and in vitro characterization of the immune stimulating activity of the Neisserial porin PorB

Induction of cell signaling events by the cholera toxin B subunit in antigen-presenting cells

Innate immunity and vaccines.

Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona Formation

Macrophage-specific TLR2 signaling mediates pathogen-induced TNF-dependent inflammatory oral bone loss

Meningococcal PorB induces a robust and diverse antigen specific T cell response as a vaccine adjuvant

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

Meningococcal porin PorB prevents cellular apoptosis in a toll-like receptor 2- and NF-kappaB-independent manner

Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1

Neisseria gonorrhoeae porin P1.B induces endosome exocytosis and a redistribution of Lamp1 to the plasma membrane.

Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia.

Neisseriae internalization by epithelial cells is enhanced by TLR2 stimulation

Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis.

Neisserial porin-induced dendritic cell activation is MyD88 and TLR2 dependent

Serum resistance of Neisseria gonorrhoeae. Does it thwart the inflammatory response and facilitate the transmission of infection?

Specific binding to differentially-expressed human CEACAMs determines the outcome of Neisseria gonorrhoeae infections along the female reproductive tract.

Studies on the effect of neisserial porins on apoptosis of Mammalian cells.

Summary and Recommendations from the National Institute of Allergy and Infectious Diseases (NIAID) Workshop "Gonorrhea Vaccines: the Way Forward".

T cell activation by TLRs: a role for TLRs in the adaptive immune response

T lymphocyte response to Neisseria gonorrhoeae porin in individuals with mucosal gonococcal infections

Testing meningococcal vaccines for mitogenicity and superantigenicity.

The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant.

The Role of TLR2 in Infection and Immunity

The TLR2 Binding Neisserial Porin PorB Enhances Antigen Presenting Cell Trafficking and Cross-presentation.

The contrasting mechanisms of serum resistance of Neisseria gonorrhoeae and group B Neisseria meningitidis.

The nature of an in vivo anti-capsular polysaccharide response is markedly influenced by the composition and/or architecture of the bacterial subcapsular domain.

The pilus and porin of Neisseria gonorrhoeae cooperatively induce Ca(2+) transients in infected epithelial cells

The reproductive cycle is a pathogenic determinant during gonococcal pelvic inflammatory disease in mice.

The role of B/T costimulatory signals in the immunopotentiating activity of neisserial porin

The role of porins in neisserial pathogenesis and immunity.

Toll-Like Receptor Ligand-Based Vaccine Adjuvants Require Intact MyD88 Signaling in Antigen-Presenting Cells for Germinal Center Formation and Antibody Production.

Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells

Toll-like receptor 2-mediated human B cell differentiation

Vaccines for gonorrhea: where are we on the curve?