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List of works by Yasuhiro Abe

A novel method for construction of gene fragment library to searching epitopes

scientific article published on 24 May 2006

Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials

scientific article published on 22 September 2010

Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2.

scientific article

Amorphous nanosilica induce endocytosis-dependent ROS generation and DNA damage in human keratinocytes.

scientific article

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

scientific article published on 04 January 2012

Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells

scientific article published on 26 September 2012

Analysis of an Impurity, N-Nitrosodimethylamine, in Valsartan Drug Substances and Associated Products Using GC-MS

scientific article published on 07 February 2019

Annexin A4 is a possible biomarker for cisplatin susceptibility of malignant mesothelioma cells ⬇️

scientific article published on April 4, 2012

Anti-inflammatory effects of a novel TNFR1-selective antagonistic TNF mutant on established murine collagen-induced arthritis

scientific article published on 01 January 2011

Application of bioactive mutant TNF alpha to a mucosal vaccine adjuvant

scientific article

Arsenic trioxide induces down-regulation of gp46 via protein oxidation: proteomics analysis of oxidative modified proteins in As2O3-treated HTLV-1-infected cells.

scientific article

Arsenic trioxide inhibits human t cell-lymphotropic virus-1-induced syncytiums by down-regulating gp46.

scientific article published in July 2009

Atomic Force Microscopic Analysis of the Effect of Lipid Composition on Liposome Membrane Rigidity.

scientific article

Biochemical and hematologic effects of polyvinylpyrrolidone-wrapped fullerene C60 after oral administration

scientific article published on January 1, 2013

Cell Type-Specific Responses of Peripheral Blood CD14-Positive Monocytes to Liposome-Encapsulated Immunostimulatory siRNA.

scientific article published in January 2016

Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist

scientific article

Creation of TNFR1-selective antagonist and its therapeutic effects

scientific article

Creation of a novel cell penetrating peptide, using a random 18mer peptides library.

scientific article

Creation of novel cell-penetrating peptides for intracellular drug delivery using systematic phage display technology originated from Tat transduction domain

scientific article

Development of an antibody proteomics system using a phage antibody library for efficient screening of biomarker proteins ⬇️

scientific article published on October 8, 2010

Distribution and histologic effects of intravenously administered amorphous nanosilica particles in the testes of mice

scientific article published on 06 March 2012

Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages.

scientific article published on 22 July 2011

Effect of protein properties on display efficiency using the M13 phage display system.

scientific article

Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages.

scientific article published on 18 January 2011

Eph receptor A10 has a potential as a target for a prostate cancer therapy.

scientific article

Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers

scientific article

Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis

scientific article published on December 2013

Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients.

scientific article

Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists

scientific article

Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning.

scientific article

Generation of a sensitive TNFR2-specific murine assays system

scientific article published on May 2016

Generation of mouse macrophages expressing membrane-bound TNF variants with selectivity for TNFR1 or TNFR2.

scientific article

Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles

scientific article published on 8 October 2012

Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors

scientific article published on 11 May 2015

Identification of new candidates as mucosal vaccine adjuvant in TNF family cytokines

scientific article published on 01 January 2011

Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.

scientific article

Intestinal absorption and biological effects of orally administered amorphous silica particles.

scientific article

Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung ⬇️

scientific article published on January 25, 2011

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

scientific article published on 12 September 2013

Mutant TNF-alpha, mTNF-K90R, is a novel candidate adjuvant for a mucosal vaccine against HIV

scientific article published on 01 April 2010

Novel protein engineering strategy for creating highly receptor-selective mutant TNFs

scientific article published on 13 August 2009

Observation of liposomes of differing lipid composition in aqueous medium by means of atomic force microscopy

scientific article published on 28 March 2016

Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency

scientific article published in March 2004

Organelle-targeted delivery of biological macromolecules using the protein transduction domain: potential applications for Peptide aptamer delivery into the nucleus.

scientific article

Potential adjuvant effect of intranasal urban aerosols in mice through induction of dendritic cell maturation.

scientific article

Potential of acute-phase proteins as biomarkers for sub-nano platinum exposure

scientific article published on 01 November 2012

Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice.

scientific article published on 4 March 2011

Quality enhancement of the non-immune phage scFv library to isolate effective antibodies

scientific article published in July 2006

Rapid and efficient high-performance liquid chromatography analysis of N-nitrosodimethylamine impurity in valsartan drug substance and its products

scientific article published on 14 August 2019

Rapid isolation of intrabody candidates by using an optimized non-immune phage antibody library.

scientific article

Recombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients.

scientific article published on 17 November 2017

Rho GDP-dissociation inhibitor alpha is associated with cancer metastasis in colon and prostate cancer.

scientific article published on March 2012

Role of amino acid residue 90 in bioactivity and receptor binding capacity of tumor necrosis factor mutants

scientific article published on 22 May 2007

Safety Studies of Nanomaterials about Intracellular Distribution and Genotoxicity ⬇️

scientific article published on 01 February 2011

Selective enhancer of tumor vascular permeability for optimization of cancer chemotherapy.

scientific article published on March 2004

Silica and titanium dioxide nanoparticles cause pregnancy complications in mice

scientific article published on 03 April 2011

Simple and highly sensitive assay system for TNFR2-mediated soluble- and transmembrane-TNF activity

scientific article published on 26 March 2008

Size-dependent immune-modulating effect of amorphous nanosilica particles.

scientific article published in September 2011

Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant

scientific article

Surface modification of amorphous nanosilica particles suppresses nanosilica-induced cytotoxicity, ROS generation, and DNA damage in various mammalian cells

scientific article

Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application ⬇️

scientific article published on January 22, 2011

TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant

scientific article published on 4 May 2009

The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models

scientific article published on 23 September 2008

The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF

scientific article published on 17 September 2009

The use of a mutant TNF-alpha as a vaccine adjuvant for the induction of mucosal immune responses

scientific article published on 30 July 2009

Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice

[Development of novel DDS technologies for optimized protein therapy by creating functional mutant proteins with antagonistic activity].

scientific article

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