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List of works by Luke A. Wiley

A Method for Sectioning and Immunohistochemical Analysis of Stem Cell-Derived 3-D Organoids

scientific article published on 12 May 2016

ASSESSMENT OF AAV SEROTYPE TROPISM IN HUMAN RETINAL EXPLANTS.

scientific article published on 21 November 2017

CEP290 gene transfer rescues Leber congenital amaurosis cellular phenotype.

scientific article published on 8 May 2014

CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration.

scientific article published on 22 March 2018

Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease

scientific article

Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds.

scientific article published on 21 December 2015

Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma

scientific article

Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis.

scientific article

Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells.

scientific article published on 23 April 2018

Gene therapy using stem cells

scientific article

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration

scientific article published on December 2015

Generation of Xeno-Free, cGMP-Compliant Patient-Specific iPSCs from Skin Biopsy

scientific article published on 14 August 2017

Mechanical properties of murine and porcine ocular tissues in compression

scientific article published on 05 March 2014

Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration

scientific article published on 13 November 2015

Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels.

scientific article published on 23 March 2016

North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13.

scientific article

Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases

scientific article

Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa

scientific article published on 18 March 2017

Prevascularized silicon membranes for the enhancement of transport to implanted medical devices.

scientific article published on 28 August 2015

Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction.

scientific article

Stem cells as tools for studying the genetics of inherited retinal degenerations

scientific article published on 11 December 2014

Superior cervical ganglionectomy induces changes in growth factor expression in the rat retina.

scientific article

The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.

scientific article

Two-photon polymerization for production of human iPSC-derived retinal cell grafts.

scientific article published on 25 March 2017

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration

scientific article published on 12 June 2017

Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration

scientific article published on 11 July 2016

WNT7A/B promote choroidal neovascularization

scientific article published on 01 June 2018

cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness

scientific article published on 29 July 2016