List of works by Martin Simard

A guide to microRNA-mediated gene silencing

scientific article published on 08 October 2018

A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans.

scientific article

A new role for the GARP complex in microRNA-mediated gene regulation

scientific article (publication date: November 2013)

A new twist in the microRNA pathway: Not Dicer but Argonaute is required for a microRNA production

scientific article published on 15 June 2010

A novel mutation in the neurofibromatosis type 1 (NF1) gene promotes skipping of two exons by preventing exon definition.

scientific article published on April 2001

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi

scientific article

Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression

scientific article published on 6 July 2012

Argonaute proteins: key players in RNA silencing

scientific article (publication date: 2008)

Biogenesis of small non-coding RNAs in animals

scientific article published on 16 February 2018

CSDE1 controls gene expression through the miRNA-mediated decay machinery

scientific article published on 11 March 2020

Developmental characterization of the microRNA-specific C. elegans Argonautes alg-1 and alg-2

scientific article (publication date: 2012)

Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span.

scientific article

Function, targets, and evolution of Caenorhabditis elegans piRNAs

scientific article published on 14 June 2012

GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

scientific article

MicroRNA-19a enhances proliferation of bronchial epithelial cells by targeting TGFβR2 gene in severe asthma.

scientific article published on 19 December 2014

Mutations in conserved residues of the C. elegans microRNA Argonaute ALG-1 identify separable functions in ALG-1 miRISC loading and target repression

scientific article (publication date: April 2014)

Novel features of a PIWI-like protein homolog in the parasitic protozoan Leishmania

scientific article

Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.

scientific article published on 23 June 2017

Poly(A)-binding proteins are required for microRNA-mediated silencing and to promote target deadenylation in C. elegans.

scientific article published on 19 April 2016

Polypyrimidine tract binding protein (hnRNP I) is possibly a conserved modulator of miRNA-mediated gene regulation

scientific article

RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans

scientific article

RNAi pathway in C. elegans: the argonautes and collaborators.

scientific article

Relationship between the development of bronchial hyperresponsiveness and the airway eosinophilia in guinea pigs following injection with Sephadex beads.

scientific article published in August 1995

SRp30c is a repressor of 3' splice site utilization.

scientific article

Sequence-specific inhibition of small RNA function

scientific article

Somatic and Germline MicroRNAs Form Distinct Silencing Complexes to Regulate Their Target mRNAs Differently

scientific article published on 20 September 2018

Structural biology: Tracing Argonaute binding

scientific article published in Nature

TEG-1 CD2BP2 controls miRNA levels by regulating miRISC stability in C. elegans and human cells

scientific article

The R148.3 Gene Modulates Caenorhabditis elegans Lifespan and Fat Metabolism

scientific article published on 15 June 2017

The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans

scientific article

The decapping scavenger enzyme DCS-1: a new modulator of miRNA turnover.

scientific article published on 19 August 2013

The human decapping scavenger enzyme DcpS modulates microRNA turnover

scientific article published on 20 November 2015

The implication of microRNAs and endo-siRNAs in animal germline and early development.

scientific article

The microRNA pathway controls germ cell proliferation and differentiation in C. elegans

scientific article

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans

scientific article

The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans

scientific article

Tumour-related microRNAs functions in Caenorhabditis elegans.

scientific article

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

scientific article published on 26 March 2008

miR-20a represses endothelial cell migration by targeting MKK3 and inhibiting p38 MAP kinase activation in response to VEGF.

scientific article published on 14 June 2012

p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells

scientific article

p38 and JNK pathways control E-selectin-dependent extravasation of colon cancer cells by modulating miR-31 transcription

scientific article published on 2 December 2016

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