List of works - Zhiyi Wei

A structural approach to decipher the neurexin and neuroligin splice isoform code

scientific article published on July 2010

Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

scientific article published on 14 January 2016

An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs

scientific article

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway

scientific article

Antiparallel coiled-coil-mediated dimerization of myosin X

scientific article

Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor

scientific article

Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions

scientific article published on 25 August 2017

Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain

scientific article

Cloning, purification, crystallization and preliminary crystallographic analysis of human phosphoglycerate mutase.

scientific article

Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family.

scientific article published on 03 February 2006

Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans

scientific article

Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion

scientific article

Crystal structure of human bisphosphoglycerate mutase

scientific article

Crystal structure of human eIF3k, the first structure of eIF3 subunits

scientific article

Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP.

scientific article published on December 2005

Crystal structure of human thioesterase superfamily member 2

scientific article

Crystal structure of the C-terminal domain of S.cerevisiae eIF5.

scientific article

Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli

scientific article

Crystal structures of human IPP isomerase: new insights into the catalytic mechanism

scientific article

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1

scientific article

Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron

scientific article

Decorating Proteins with “Sweets” Is a Flexible Matter ⬇️

scientific article published on January 8, 2013

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

scientific article

Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia

scientific article

F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis

scientific article published on 06 November 2020

Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing

scientific article

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

scientific article

Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6

scientific article

Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures

scientific article

Myosin VI undergoes cargo-mediated dimerization

scientific article

Orthosteric and allosteric action of the C5a receptor antagonists

scientific article published on 04 June 2018

Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase

scientific article

Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase

scientific article

Solution structure of synbindin atypical PDZ domain and interaction with syndecan-2

scientific article

Structural Basis of the Binding of Merlin FERM Domain to the E3 Ubiquitin Ligase Substrate Adaptor DCAF1

scientific article

Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin

scientific article

Structural basis of cargo recognitions for class V myosins

scientific article

Structural basis of diverse membrane target recognitions by ankyrins

scientific article

Structural basis of kindlin-mediated integrin recognition and activation.

scientific article published on 24 July 2017

Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity

scientific article published on 10 January 2020

Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor

scientific article

Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics

scientific article published on 08 February 2019

Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.

scientific article published on 7 December 2017

Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2

scientific article published on 25 February 2019

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

scientific article published on 10 November 2014

Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo

scientific article

Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride

scientific article published on 15 July 2020

Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride

scientific article published on 27 October 2020

Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function

scientific article

Structure of the 2 2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarbonylase/synthase complex

scientific article published on 15 July 2008

Structures of the Human PGD Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition

scientific article published on 13 September 2018

Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1

scientific article

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

scientific article

The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis.

scientific article

List of works by Zhiyi Wei

A structural approach to decipher the neurexin and neuroligin splice isoform code

Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs

Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway

Antiparallel coiled-coil-mediated dimerization of myosin X

Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor

Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions

Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain

Cloning, purification, crystallization and preliminary crystallographic analysis of human phosphoglycerate mutase.

Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family.

Crystal structure of homoserine O-acetyltransferase from Leptospira interrogans

Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion

Crystal structure of human bisphosphoglycerate mutase

Crystal structure of human eIF3k, the first structure of eIF3 subunits

Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP.

Crystal structure of human thioesterase superfamily member 2

Crystal structure of the C-terminal domain of S.cerevisiae eIF5.

Crystal structure of the RNA-guided immune surveillance Cascade complex in Escherichia coli

Crystal structures of human IPP isomerase: new insights into the catalytic mechanism

Crystal structures of the extracellular domain of LRP6 and its complex with DKK1

Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron

Decorating Proteins with “Sweets” Is a Flexible Matter ⬇️

Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

Dysfunction in the βII spectrin-dependent cytoskeleton underlies human arrhythmia

F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis

Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

Lipid-Induced conformational switch controls fusion activity of longin domain SNARE Ykt6

Liprin-mediated large signaling complex organization revealed by the liprin-α/CASK and liprin-α/liprin-β complex structures

Myosin VI undergoes cargo-mediated dimerization

Orthosteric and allosteric action of the C5a receptor antagonists

Phosphorylation of DCC by ERK2 is facilitated by direct docking of the receptor P1 domain to the kinase

Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase

Solution structure of synbindin atypical PDZ domain and interaction with syndecan-2

Structural Basis of the Binding of Merlin FERM Domain to the E3 Ubiquitin Ligase Substrate Adaptor DCAF1

Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin

Structural basis of cargo recognitions for class V myosins

Structural basis of diverse membrane target recognitions by ankyrins

Structural basis of kindlin-mediated integrin recognition and activation.

Structural basis of liprin-α-promoted LAR-RPTP clustering for modulation of phosphatase activity

Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor

Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics

Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.

Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2

Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo

Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride

Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride

Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function

Structure of the 2 2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarbonylase/synthase complex

Structures of the Human PGD Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition

Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis.