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List of works by Isabelle Landrieu

1H, 15N and 13C assignments of the N-terminal domain of the Mediator complex subunit MED26.

scientific article

A Phosphorylation-Induced Turn Defines the Alzheimer's Disease AT8 Antibody Epitope on the Tau Protein

scientific article published on 16 April 2015

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge

scientific article published in 2014

A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana

scientific article

A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.

scientific article published on 19 September 2016

Accepting its Random Coil Nature Allows a Partial NMR Assignment of the Neuronal Tau Protein

scholarly article by Caroline Smet published in November 2004

Adoption of a Turn Conformation Drives the Binding Affinity of p53 C-Terminal Domain Peptides to 14-3-3σ

scientific article published on 03 January 2020

Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules

scientific article published on 12 December 2008

Arabidopsis PASTICCINO2 is an antiphosphatase involved in regulation of cyclin-dependent kinase A.

scientific article published on 12 May 2006

Assignment of the 1H, 13C and 15N resonances and secondary structure of the monomeric p13suc1 protein of Saccharomyces pombe

scientific article published on 01 June 2002

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation

scientific article published on 07 May 2019

Backbone chemical shift assignments of human 14-3-3σ

scientific article published on 30 October 2018

Cell signaling, post-translational protein modifications and NMR spectroscopy

scientific article

Characterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25

scientific article

Characterization of Neuronal Tau Protein as a Target of Extracellular Signal-regulated Kinase

scientific article published on 8 February 2016

Characterization of the AT180 epitope of phosphorylated Tau protein by a combined nuclear magnetic resonance and fluorescence spectroscopy approach

scientific article

Characterization of the Arabidopsis thaliana Arath;CDC25 dual-specificity tyrosine phosphatase.

scientific article published in September 2004

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions ⬇️

scientific article published on April 2011

Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides

scientific article published on July 2005

Direct Crosstalk Between -GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.

scientific article

ELISE NMR: experimental liquid sealing of NMR samples

scientific article

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor

scientific article published on 01 November 2019

Exploring the molecular function of PIN1 by nuclear magnetic resonance

scientific article published on June 2006

H/D exchange of a 15N labelled Tau fragment as measured by a simple Relax-EXSY experiment

scientific article published on 19 October 2014

Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B

scientific article

High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments

scientific article published on 01 July 2005

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

scientific article

Identification of a Plasmodium falciparum inhibitor-2 motif involved in the binding and regulation activity of protein phosphatase type 1

scientific article (publication date: October 2014)

Identification of the Tau phosphorylation pattern that drives its aggregation

scientific article published on 7 August 2017

Identification ofYHR019 inSaccharomyces cerevisiae chromosome VIII as the gene for the cytosolic asparaginyl-tRNA synthetase ⬇️

scientific article published on April 30, 1998

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy

scientific article

Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

scientific article published on 17 May 2018

Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau

scientific article

Isomerization and Oligomerization of Truncated and Mutated Tau Forms by FKBP52 are Independent Processes

scientific article

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

scientific article published on 21 June 2019

Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy

scientific article published in 2014

Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta

scientific article

Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry.

scientific article

Microtubule and MAPs: thermodynamics of complex formation by AUC, ITC, fluorescence, and NMR.

scientific article published on January 2010

Modulators of 14-3-3 Protein-Protein Interactions ⬇️

scientific article

Molecular basis for an ancient partnership between prolyl isomerase Pin1 and phosphatase inhibitor-2

scientific article

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

scientific article

Monitoring of the ethionamide pro-drug activation in mycobacteria by (1)H high resolution magic angle spinning NMR.

scientific article published in June 2005

NMR Meets Tau: Insights into Its Function and Pathology

scientific article

NMR analysis of a Tau phosphorylation pattern

scientific article published in March 2006

NMR investigation of the interaction between the neuronal protein tau and the microtubules

scientific article published on 21 February 2007

NMR observation of Tau in Xenopus oocytes.

scientific article published on 14 March 2008

NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.

scientific article published on 14 September 2017

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease

scientific article published on August 2010

Neurofibrillary degeneration of the Alzheimer-type: an alternate pathway to neuronal apoptosis?

scientific article

Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein

article

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

scientific article published on 27 December 2016

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation

scientific article published on 09 February 2015

Phosphorylated full-length Tau interacts with 14-3-3 proteins via two short phosphorylated sequences, each occupying a binding groove of 14-3-3 dimer

scientific article published on 26 September 2020

Phosphorylation in intrinsically disordered regions regulates the activity of Neurogenin2.

scientific article

Pin1: a therapeutic target in Alzheimer neurodegeneration

scientific article published on December 2002

Prevention of tau seeding and propagation by immunotherapy with a central tau epitope antibody.

scientific article

Proline Conformation in a Functional Tau Fragment

scientific article published on 2 December 2015

Proline-directed random-coil chemical shift values as a tool for the NMR assignment of the tau phosphorylation sites

scientific article published in January 2004

Ranking high affinity ligands of low solubility by NMR spectroscopy

scientific article

Recombinant Production of the p10CKS1AtProtein fromArabidopsis thalianaand13C and15N Double-Isotopic Enrichment for NMR Studies

article

Regions of tau implicated in the paired helical fragment core as defined by NMR.

scientific article

Regulation of Pin1 peptidyl-prolylcis/transisomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein

scholarly article by Caroline Smet published in July 2005

Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain

scientific article published on 29 July 2017

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

scientific article published on 07 August 2019

Selective backbone labelling of ILV methyl labelled proteins

scientific article published on 14 March 2009

Selective intracellular accumulation of the major metabolite issued from the activation of the prodrug ethionamide in mycobacteria

scientific article published on 8 August 2006

Set-up and screening of a fragment library targeting the 14-3-3 protein interface

scientific article published on 22 July 2019

Single Domain Antibody Fragments as New Tools for the Detection of Neuronal Tau Protein in Cells and in Mice Studies

scientific article published on 19 August 2019

Solution NMR study of the monomeric form of p13suc1 protein sheds light on the hinge region determining the affinity for a phosphorylated substrate

scientific article published on 25 January 2002

Solution Structure of the N-Terminal Domain of Mediator Subunit MED26 and Molecular Characterization of Its Interaction with EAF1 and TAF7.

scientific article published on 9 September 2017

Solution structure of the single-domain prolyl cis/trans isomerase PIN1At from Arabidopsis thaliana

scientific article

Spectroscopic studies of GSK3{beta} phosphorylation of the neuronal tau protein and its interaction with the N-terminal domain of apolipoprotein E.

scientific article published on 2 August 2010

Stabilizer-Guided Inhibition of Protein-Protein Interactions

scientific article

Stabilizer-Guided Inhibition of Protein-Protein Interactions

Structural Basis of Tau Interaction With BIN1 and Regulation by Tau Phosphorylation

scholarly article by Alessia Lasorsa published in January 2018

Structural analysis of Escherichia coli OpgG, a protein required for the biosynthesis of osmoregulated periplasmic glucans.

scientific article

Structural and functional characterization of the interaction between cyclophilin B and a heparin-derived oligosaccharide

scientific article published on 12 September 2007

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.

scientific article

Structural basis for the non-immunosuppressive character of the cyclosporin A analogue Debio 025.

scientific article published in June 2010

Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein

scientific article published on 9 November 2011

Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy

scientific article published on 01 October 2006

Studying Posttranslational Modifications by In-Cell NMR

scientific article published on 01 April 2008

Studying the natively unfolded neuronal Tau protein by solution NMR spectroscopy

scientific article

Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly

scientific article published on 12 July 2011

Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation.

scientific article

Tau aggregation in Alzheimer's disease: what role for phosphorylation?

scientific article published on 23 January 2007

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

scientific article published on 25 August 2012

Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domain

scientific article published on 23 September 2015

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

scientific article

The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation

scientific article published on 11 January 2018

The Peptidyl–Prolyl Isomerase and Chaperone Par27 of Bordetella pertussis as the Prototype for a New Group of Parvulins

scientific article published on 09 November 2007

The Study of Posttranslational Modifications of Tau Protein by Nuclear Magnetic Resonance Spectroscopy: Phosphorylation of Tau Protein by ERK2 Recombinant Kinase and Rat Brain Extract, and Acetylation by Recombinant Creb-Binding Protein

scientific article published in January 2017

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

scientific article published on 01 March 2019

The peptidyl prolyl cis/trans-isomerase Pin1 recognizes the phospho-Thr212-Pro213 site on Tau.

scientific article published in February 2004

The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges

scientific article

Towards understanding the phosphorylation code of tau.

scientific article published on August 2012

Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges

scientific article published in Scientific Reports

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.

scientific article published on 2 March 2013

Zinc Binding to Tau Influences Aggregation Kinetics and Oligomer Distribution

scientific article published on 27 November 2019

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