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List of works by Brent R Stockwell

A simplified cell-based assay to identify coronavirus 3CL protease inhibitors

scientific article published on 29 August 2020

Biological Mechanism Profiling Using an Annotated Compound Library ⬇️

scientific article published on September 1, 2003

Cysteine depletion induces pancreatic tumor ferroptosis in mice

scientific article published on 01 April 2020

Design and synthesis of Pictet–Spengler condensation products that exhibit oncogenic-RAS synthetic lethality and induce non-apoptotic cell death ⬇️

scientific article published on June 30, 2012

Design of small molecules that compete with nucleotide binding to an engineered oncogenic KRAS allele.

scientific article published on 9 January 2018

Detecting Spatial Patterns in Biological Array Experiments ⬇️

scientific article published on August 1, 2003

Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis.

scientific article published on 7 March 2018

Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents

scientific article published on 29 October 2019

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

scientific article published on 07 April 2022

Energy-stress-mediated AMPK activation inhibits ferroptosis

scientific article published on 06 February 2020

Functional Model of Metabolite Gating by Human Voltage-Dependent Anion Channel 2 ⬇️

scientific article published on April 6, 2011

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

scientific article published on 09 May 2016

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Heat stress induces ferroptosis-like cell death in plants.

scientific article published on 18 January 2017

K-RasG12D Has a Potential Allosteric Small Molecule Binding Site

scientific article published on 14 May 2019

MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling

scientific article published on 20 February 2020

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

Mutant Huntingtin Alters Cell Fate in Response to Microtubule Depolymerization via the GEF-H1-RhoA-ERK Pathway ⬇️

scientific article published on September 21, 2010

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

scientific article published on 09 August 2016

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

scientific article

Probing the role of homomeric and heteromeric receptor interactions in TGF-β signaling using small molecule dimerizers ⬇️

scientific article published on June 18, 1998

Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis

scientific article published in 2024

Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

scientific article published on 14 January 2020

Regulation of lipid peroxidation and ferroptosis in diverse species.

scientific article published in May 2018

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

scientific article published on 16 October 2020

TGF-β-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-β type I receptor fusion proteins ⬇️

scientific article published on July 1, 1998

Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy

scientific article published on 27 March 2018

The Chemistry and Biology of Ferroptosis

scientific article published on 02 April 2020

Toward a Microparticle-Based System for Pooled Assays of Small Molecules in Cellular Contexts

scientific article published on 24 January 2018

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

scientific article

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