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Authors whose works are in public domain in at least one jurisdiction

List of works by Pedro A. Lazo

1-50 of 96 results

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

scientific article

Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK

scientific article

Tetraspanin proteins as organisers of membrane microdomains and signalling complexes.

scientific article

Aberrant expression of tetraspanin molecules in B-cell chronic lymphoproliferative disorders and its correlation with normal B-cell maturation

scientific article published on 01 August 2005

The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer

scientific article

c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)

scientific article

Long-distance activation of the Myc protooncogene by provirus insertion in Mlvi-1 or Mlvi-4 in rat T-cell lymphomas

scientific article published on January 1, 1990

Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

scientific article

VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

scientific article

Roles of VRK1 as a new player in the control of biological processes required for cell division.

scientific article published on 14 April 2011

Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1

scientific article

The subcellular localization of vaccinia-related kinase-2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines

scientific article

Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein

scientific article

Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation

scientific article

Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway

scientific article

p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop

scientific article

Involvement of SNAP-23 and syntaxin 6 in human neutrophil exocytosis

scientific article (publication date: October 2000)

Apoptosis protection and survival signal by the CD53 tetraspanin antigen

scientific article published in February 2003

A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection.

scientific article

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage

scientific article

Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

scientific article

JC virus in the pathogenesis of colorectal cancer, an etiological agent or another component in a multistep process?

scientific article

Deletion in human chromosome region 12q13-15 by integration of human papillomavirus DNA in a cervical carcinoma cell line.

scientific article

The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism

scientific article

Alteration of the VRK1-p53 autoregulatory loop in human lung carcinomas

scientific article published on 8 August 2007

Amino acids and glucose utilization by different metabolic pathways in ascites-tumour cells

scientific article published on 01 June 1981

VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage

scientific article

Differential Inhibitor Sensitivity between Human Kinases VRK1 and VRK2

scientific article published on August 4, 2011

VRK2 anchors KSR1-MEK1 to endoplasmic reticulum forming a macromolecular complex that compartmentalizes MAPK signaling

scientific article

Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expression

scientific article

Identification of two isoforms of the vesicle-membrane fusion protein SNAP-23 in human neutrophils and HL-60 cells.

scientific article

Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis

scientific article published on 7 December 2015

Human VRK2 (Vaccinia-related Kinase 2) Modulates Tumor Cell Invasion by Hyperactivation of NFAT1 and Expression of Cyclooxygenase-2

scientific article published on October 26, 2012

Cancer as a reprogramming-like disease: Implications in tumor development and treatment

scientific article published on February 24, 2010

Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1

scientific article (publication date: March 1999)

Genetic alterations by human papillomaviruses in oncogenesis

scientific article published on March 30, 1992

VRK2 inhibits mitogen-activated protein kinase signaling and inversely correlates with ErbB2 in human breast cancer

scientific article

Vaccinia-related kinase 1 (VRK1) confers resistance to DNA-damaging agents in human breast cancer by affecting DNA damage response

scientific article

Activation of multiple genes by provirus integration in the Mlvi-4 locus in T-cell lymphomas induced by Moloney murine leukemia virus

scientific article published on May 1, 1990

The Mlvi-1 locus involved in the induction of rat T-cell lymphomas and the pvt-1/Mis-1 locus are identical.

scientific article published on May 1989

Vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun-dependent signaling

scientific article

VRK1 chromatin kinase phosphorylates H2AX and is required for foci formation induced by DNA damage

scientific article

Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications

scientific article

The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53

scientific article

Interference with p53 functions in human viral infections, a target for novel antiviral strategies?

scientific article published on July 2011

The spinal muscular atrophy with pontocerebellar hypoplasia gene VRK1 regulates neuronal migration through an amyloid-β precursor protein-dependent mechanism.

scientific article

VRK1 phosphorylates and protects NBS1 from ubiquitination and proteasomal degradation in response to DNA damage

scientific journal article

VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle

scientific article published on 12 June 2015