List of works - Timm C Harder

A candidate phocid herpesvirus vaccine that provides protection against feline herpesvirus infection

scientific article published on 01 December 2001

A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens.

scientific article published on 3 November 2016

Active surveillance for avian influenza virus infection in wild birds by analysis of avian fecal samples from the environment.

scientific article published in April 2009

Alterations in hemagglutinin receptor-binding specificity accompany the emergence of highly pathogenic avian influenza viruses

scientific article published on 04 March 2015

Analysis of influenza A viruses of subtype H1 from wild birds, turkeys and pigs in Germany reveals interspecies transmission events.

scientific article

Avian influenza H7N9/13 and H7N7/13: a comparative virulence study in chickens, pigeons, and ferrets

scientific article

Avian influenza virus risk assessment in falconry.

scientific article

Benefits and Limits of Egg Yolk vs. Serum Samples for Avian Influenza Virus Serosurveillance

scientific article published on June 2016

Broad spectrum reactivity versus subtype specificity—Trade-offs in serodiagnosis of influenza A virus infections by competitive ELISA ⬇️

scientific article published on January 12, 2011

Canine distemper virus from diseased large felids: biological properties and phylogenetic relationships.

scientific article published in March 1996

Canine distemper virus in Lake Baikal seals (Phoca sibirica).

scientific article published in May 1996

Chances and limitations of wild bird monitoring for the avian influenza virus H5N1--detection of pathogens highly mobile in time and space

scientific article

ClassyFlu: classification of influenza A viruses with Discriminatively trained profile-HMMs

scientific article published on 03 January 2014

Comparative analysis of the attachment protein gene (H) of dolphin morbillivirus.

scientific article published on January 1996

Comparative immunological characterization of type-specific and conserved B-cell epitopes of pinniped, felid and canid herpesviruses

scientific article published on 01 January 1994

Comparing introduction to Europe of highly pathogenic avian influenza viruses A(H5N8) in 2014 and A(H5N1) in 2005.

scientific article published on 18 December 2014

Consecutive natural influenza a virus infections in sentinel mallards in the evident absence of subtype-specific hemagglutination inhibiting antibodies.

scientific article published on 22 July 2012

Continuous cell lines from the Muscovy duck as potential replacement for primary cells in the production of avian vaccines

scientific article published on 26 January 2016

Control and eradication strategies for classic fowl plague in Germany and the European Union

scientific article published on March 2006

Controlling Avian Influenza Virus in Bangladesh: Challenges and Recommendations

scientific article published on 12 July 2020

Design and validation of a microarray for detection, hemagglutinin subtyping, and pathotyping of avian influenza viruses.

scientific article published on 03 December 2008

Detection of phocid distemper virus RNA in seal tissues using slot hybridization and the polymerase chain reaction amplification assay: genetic evidence that the virus is distinct from canine distemper virus

scientific article published on April 1, 1991

Detection of the new influenza A subtype H1pdmN2 in a pig holding with severe respiratory symptoms

scientific article

Distinction of subtype-specific antibodies against European porcine influenza viruses by indirect ELISA based on recombinant hemagglutinin protein fragment-1 ⬇️

scientific article published on July 30, 2013

Dynamics of specific antibody responses induced in mallards after infection by or immunization with low pathogenicity avian influenza viruses

scientific article published in March 2010

Effect of swab matrix, storage time, and temperature on detection of avian influenza virus RNA in swab samples

scientific article published in December 2012

Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15.

scientific article published on 2 April 2015

Epidemiological and Molecular Analysis of an Outbreak of Highly Pathogenic Avian Influenza H5N8 clade 2.3.4.4 in a German Zoo: Effective Disease Control with Minimal Culling.

scientific article

Epidemiological and ornithological aspects of outbreaks of highly pathogenic avian influenza virus H5N1 of Asian lineage in wild birds in Germany, 2006 and 2007.

scientific article published on April 2009

European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and Swine influenza virus subtypes identified in 14 European countries from 2010 to 2013.

scientific article

Evaluation of the AmpliSensor PCR and the SHARP signal detection system for the early prediction of symptomatic CMV infection in solid transplant recipients

scientific article published on 01 June 1999

Evolutionary features of influenza A/H5N1 virus populations in Egypt: poultry and human health implications.

scientific article published on 11 April 2016

Evolutionary trajectories and diagnostic challenges of potentially zoonotic avian influenza viruses H5N1 and H9N2 co-circulating in Egypt.

scientific article

Expanded Cocirculation of Stable Subtypes, Emerging Lineages, and New Sporadic Reassortants of Porcine Influenza Viruses in Swine Populations in Northwest Germany ⬇️

scientific article published on July 3, 2013

Experimental infection and natural contact exposure of dogs with avian influenza virus (H5N1).

scientific article published on February 2008

Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1).

scientific article published on July 2008

Failure of productive infection of Mallards (Anas platyrhynchos) with H16 subtype of avian influenza viruses.

scientific article

Field study on swine influenza virus (SIV) infection in weaner pigs and sows.

scientific article

Full genome sequence analysis of a newly emerged QX-like infectious bronchitis virus from Sudan reveals distinct spots of recombination.

scientific article

Genetic characterization of the unique short segment of phocid herpesvirus type 1 reveals close relationships among alphaherpesviruses of hosts of the order Carnivora.

scientific article

Health status of seabirds and coastal birds found at the German North Sea coast ⬇️

scientific article published on July 19, 2012

Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not.

scientific article published on 5 June 2017

Highly pathogenic avian influenza A(H5N8) outbreaks: protection and management of exposed people in Europe, 2014/15 and 2016.

scientific article published on December 2016

Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans

scientific article published on August 2008

Highly pathogenic avian influenza virus (H5N1) in frozen duck carcasses, Germany, 2007.

scientific article published on February 2009

Highly pathogenic avian influenza virus H5N1 from Egypt escapes vaccine-induced immunity but confers clinical protection against a heterologous clade 2.2.1 Egyptian isolate.

scientific article published on 15 January 2011

Highly pathogenic avian influenza virus infection of mallards with homo- and heterosubtypic immunity induced by low pathogenic avian influenza viruses

scientific article

Highly pathogenic avian influenza virus subtype H5N1 in mute swans (Cygnus olor) in Central Bosnia

scientific article

Influence of maternal immunity on vaccine efficacy and susceptibility of one day old chicks against Egyptian highly pathogenic avian influenza H5N1.

scientific article published on 07 August 2011

Influenza A Virus Infection in Pigs Attracts Multifunctional and Cross-Reactive T Cells to the Lung.

scientific article

Influenza A virus infections in marine mammals and terrestrial carnivores.

scientific article

Influenza A(H5N8) Virus Similar to Strain in Korea Causing Highly Pathogenic Avian Influenza in Germany

scientific article published on May 2015

Insights into genetic diversity and biological propensities of potentially zoonotic avian influenza H9N2 viruses circulating in Egypt

scientific article published on 29 August 2017

Intertypic differentiation and detection of intratypic variants among canine and phocid morbillivirus isolates by kinetic neutralization using a novel immunoplaque assay

scientific article published on 01 January 1993

Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on.

scientific article

Investigations on course and outcome of phocine distemper virus infection in harbour seals (Phoca vitulina) exposed to polychlorinated biphenyls. Virological and serological investigations

scientific article published on February 1, 1992

Isolation and genetic characterization of a novel 2.2.1.2a H5N1 virus from a vaccinated meat-turkeys flock in Egypt

scientific article published on 09 March 2017

Limited susceptibility of chickens, turkeys, and mice to pandemic (H1N1) 2009 virus

scientific article

Minute excretion of highly pathogenic avian influenza virus A/chicken/Indonesia/2003 (H5N1) from experimentally infected domestic pigeons (Columbia livia) and lack of transmission to sentinel chickens

scientific article

Molecular characterization and baculovirus expression of the glycoprotein B of a seal herpesvirus (phocid herpesvirus-1).

scientific article published on January 1997

Molecular subtyping of European swine influenza viruses and scaling to high-throughput analysis.

scientific article published on 10 January 2018

Morbillivirus antibodies of maternal origin in harbour seal pups. (Phoca vitulina)

scientific article published on 01 June 1993

Multiple dose vaccination with heterologous H5N2 vaccine: immune response and protection against variant clade 2.2.1 highly pathogenic avian influenza H5N1 in broiler breeder chickens

scientific article published on 13 July 2011

Multiple introductions of reassorted highly pathogenic avian influenza viruses (H5N8) clade 2.3.4.4b causing outbreaks in wild birds and poultry in Egypt.

scientific article published on 14 December 2017

Natural Reassortants of Potentially Zoonotic Avian Influenza Viruses H5N1 and H9N2 from Egypt Display Distinct Pathogenic Phenotypes in Experimentally Infected Chickens and Ferrets

scientific article published on 20 September 2017

New LightCycler PCR for rapid and sensitive quantification of parvovirus B19 DNA guides therapeutic decision-making in relapsing infections

scientific article

New real time and conventional RT-PCRs for updated molecular diagnosis of infectious bronchitis virus infection (IBV) in chickens in Egypt associated with frequent co-infections with avian influenza and Newcastle Disease viruses

scientific article published on 20 March 2017

New real-time reverse transcriptase polymerase chain reactions facilitate detection and differentiation of novel A/H1N1 influenza virus in porcine and human samples

scientific article

No virological evidence for an influenza A - like virus in European bats

scientific article published on 17 May 2014

Novel real-time PCR-based patho- and phylotyping of potentially zoonotic avian influenza A subtype H5 viruses at risk of incursion into Europe in 2017.

scientific article

Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus.

scientific article published on 13 March 2014

Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread

scientific article published on 7 September 2015

Pathology of natural infections by H5N1 highly pathogenic avian influenza virus in mute (Cygnus olor) and whooper (Cygnus cygnus) swans.

scientific article published in March 2007

Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals.

scientific article published on 26 November 2015

Possible sources and spreading routes of highly pathogenic avian influenza virus subtype H5N1 infections in poultry and wild birds in Central Europe in 2007 inferred through likelihood analyses

scientific article published on 17 July 2010

Poultry food products--a source of avian influenza virus transmission to humans?

scientific article published on 11 December 2015

Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial

scientific article published on 06 June 2006

Purification of phocid herpesvirus type 1 glycoproteins B and D and pilot studies of immunogenicity in mice.

scientific article published on 11 October 2005

Rapid and sensitive detection of immunoglobulin M (IgM) and IgG antibodies against canine distemper virus by a new recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay.

scientific article

Rapid detection and subtyping of European swine influenza viruses in porcine clinical samples by haemagglutinin- and neuraminidase-specific tetra- and triplex real-time RT-PCRs

scientific article

Rapid detection by reverse hybridization of mutations in the UL97 gene of human cytomegalovirus conferring resistance to ganciclovir.

scientific article

Rapid molecular discrimination between infection with wild-type varicella-zoster virus and varicella vaccine virus.

scientific article published in October 2002

Rapid molecular subtyping by reverse transcription polymerase chain reaction of the neuraminidase gene of avian influenza A viruses.

scientific article published on 8 October 2008

Rapid pathotyping of recent H5N1 highly pathogenic avian influenza viruses and of H5 viruses with low pathogenicity by RT-PCR and restriction enzyme cleavage pattern (RECP).

scientific article published on 30 October 2008

Reassortants of pandemic influenza A virus H1N1/2009 and endemic porcine HxN2 viruses emerge in swine populations in Germany ⬇️

scientific article published on May 23, 2012

Reassorted pandemic (H1N1) 2009 influenza A virus discovered from pigs in Germany.

scientific article

Respiratory disease due to mixed viral infections in poultry flocks in Egypt between 2017 and 2018: Upsurge of highly pathogenic avian influenza virus subtype H5N8 since 2018

scientific article published on 11 July 2019

Riems influenza a typing array (RITA): An RT-qPCR-based low density array for subtyping avian and mammalian influenza a viruses

scientific article published on 03 June 2016

Round table on morbilliviruses in marine mammals

scientific article published on November 1, 1992

Sample preparation for avian and porcine influenza virus cDNA amplification simplified: Boiling vs. conventional RNA extraction

scientific article published on 27 April 2015

Saving resources: Avian influenza surveillance using pooled swab samples and reduced reaction volumes in real-time RT-PCR ⬇️

scientific article published on August 25, 2012

Seal gammaherpesviruses: identification, characterisation and epidemiology

scientific article published on 01 July 2003

Sequence diversity of the haemagglutinin open reading frame of recent highly pathogenic avian influenza H5N1 isolates from Egypt.

scientific article published on 9 August 2009

Serologic survey for phocid herpesvirus-1 and -2 in marine mammals from Alaska and Russia ⬇️

scientific article published on July 1, 1997

Simultaneous detection and differentiation by multiplex real time RT-PCR of highly pathogenic avian influenza subtype H5N1 classic (clade 2.2.1 proper) and escape mutant (clade 2.2.1 variant) lineages in Egypt

scientific article

Spatiotemporal Analysis of the Genetic Diversity of Seal Influenza A(H10N7) Virus, Northwestern Europe

scientific article published on 27 January 2016

Spot synthesis of overlapping peptides on paper membrane supports enables the identification of linear monoclonal antibody binding determinants on morbillivirus phosphoproteins

scientific article published on 01 May 1995

Swarm incursions of reassortants of highly pathogenic avian influenza virus strains H5N8 and H5N5, clade 2.3.4.4b, Germany, winter 2016/17.

scientific article published on 8 January 2018

Systemic influenza virus H5N1 infection in cats after gastrointestinal exposure ⬇️

scientific article published on August 24, 2010

Vaccines against influenza A viruses in poultry and swine: Status and future developments

scientific article published on 31 March 2015

Variations in the severity of phocid herpesvirus type 1 infections with age in grey seals and harbour seals

scientific article published on 01 May 2002

Viral antigen distribution in organs of cattle experimentally infected with rinderpest virus.

scientific article published in November 1993

Virological Monitoring of White Storks (Ciconia ciconia) for Avian Influenza

scientific article published on 01 December 2009

[Simplified identification and differentiation of feline, canine and phocine herpesvirus isolates using monoclonal antibodies]

scientific article published on 01 October 1994

List of works by Timm C Harder

A candidate phocid herpesvirus vaccine that provides protection against feline herpesvirus infection

A genetically engineered H5 protein expressed in insect cells confers protection against different clades of H5N1 highly pathogenic avian influenza viruses in chickens.

Active surveillance for avian influenza virus infection in wild birds by analysis of avian fecal samples from the environment.

Alterations in hemagglutinin receptor-binding specificity accompany the emergence of highly pathogenic avian influenza viruses

Analysis of influenza A viruses of subtype H1 from wild birds, turkeys and pigs in Germany reveals interspecies transmission events.

Avian influenza H7N9/13 and H7N7/13: a comparative virulence study in chickens, pigeons, and ferrets

Avian influenza virus risk assessment in falconry.

Benefits and Limits of Egg Yolk vs. Serum Samples for Avian Influenza Virus Serosurveillance

Broad spectrum reactivity versus subtype specificity—Trade-offs in serodiagnosis of influenza A virus infections by competitive ELISA ⬇️

Canine distemper virus from diseased large felids: biological properties and phylogenetic relationships.

Canine distemper virus in Lake Baikal seals (Phoca sibirica).

Chances and limitations of wild bird monitoring for the avian influenza virus H5N1--detection of pathogens highly mobile in time and space

ClassyFlu: classification of influenza A viruses with Discriminatively trained profile-HMMs

Comparative analysis of the attachment protein gene (H) of dolphin morbillivirus.

Comparative immunological characterization of type-specific and conserved B-cell epitopes of pinniped, felid and canid herpesviruses

Comparing introduction to Europe of highly pathogenic avian influenza viruses A(H5N8) in 2014 and A(H5N1) in 2005.

Consecutive natural influenza a virus infections in sentinel mallards in the evident absence of subtype-specific hemagglutination inhibiting antibodies.

Continuous cell lines from the Muscovy duck as potential replacement for primary cells in the production of avian vaccines

Control and eradication strategies for classic fowl plague in Germany and the European Union

Controlling Avian Influenza Virus in Bangladesh: Challenges and Recommendations

Design and validation of a microarray for detection, hemagglutinin subtyping, and pathotyping of avian influenza viruses.

Detection of phocid distemper virus RNA in seal tissues using slot hybridization and the polymerase chain reaction amplification assay: genetic evidence that the virus is distinct from canine distemper virus

Detection of the new influenza A subtype H1pdmN2 in a pig holding with severe respiratory symptoms

Distinction of subtype-specific antibodies against European porcine influenza viruses by indirect ELISA based on recombinant hemagglutinin protein fragment-1 ⬇️

Dynamics of specific antibody responses induced in mallards after infection by or immunization with low pathogenicity avian influenza viruses

Effect of swab matrix, storage time, and temperature on detection of avian influenza virus RNA in swab samples

Emergence of a novel cluster of influenza A(H5N1) virus clade 2.2.1.2 with putative human health impact in Egypt, 2014/15.

Epidemiological and Molecular Analysis of an Outbreak of Highly Pathogenic Avian Influenza H5N8 clade 2.3.4.4 in a German Zoo: Effective Disease Control with Minimal Culling.

Epidemiological and ornithological aspects of outbreaks of highly pathogenic avian influenza virus H5N1 of Asian lineage in wild birds in Germany, 2006 and 2007.

European surveillance network for influenza in pigs: surveillance programs, diagnostic tools and Swine influenza virus subtypes identified in 14 European countries from 2010 to 2013.

Evaluation of the AmpliSensor PCR and the SHARP signal detection system for the early prediction of symptomatic CMV infection in solid transplant recipients

Evolutionary features of influenza A/H5N1 virus populations in Egypt: poultry and human health implications.

Evolutionary trajectories and diagnostic challenges of potentially zoonotic avian influenza viruses H5N1 and H9N2 co-circulating in Egypt.

Expanded Cocirculation of Stable Subtypes, Emerging Lineages, and New Sporadic Reassortants of Porcine Influenza Viruses in Swine Populations in Northwest Germany ⬇️

Experimental infection and natural contact exposure of dogs with avian influenza virus (H5N1).

Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1).

Failure of productive infection of Mallards (Anas platyrhynchos) with H16 subtype of avian influenza viruses.

Field study on swine influenza virus (SIV) infection in weaner pigs and sows.

Full genome sequence analysis of a newly emerged QX-like infectious bronchitis virus from Sudan reveals distinct spots of recombination.

Genetic characterization of the unique short segment of phocid herpesvirus type 1 reveals close relationships among alphaherpesviruses of hosts of the order Carnivora.

Health status of seabirds and coastal birds found at the German North Sea coast ⬇️

Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not.

Highly pathogenic avian influenza A(H5N8) outbreaks: protection and management of exposed people in Europe, 2014/15 and 2016.

Highly pathogenic avian influenza virus (H5N1) in experimentally infected adult mute swans

Highly pathogenic avian influenza virus (H5N1) in frozen duck carcasses, Germany, 2007.

Highly pathogenic avian influenza virus H5N1 from Egypt escapes vaccine-induced immunity but confers clinical protection against a heterologous clade 2.2.1 Egyptian isolate.

Highly pathogenic avian influenza virus infection of mallards with homo- and heterosubtypic immunity induced by low pathogenic avian influenza viruses

Highly pathogenic avian influenza virus subtype H5N1 in mute swans (Cygnus olor) in Central Bosnia

Influence of maternal immunity on vaccine efficacy and susceptibility of one day old chicks against Egyptian highly pathogenic avian influenza H5N1.

Influenza A Virus Infection in Pigs Attracts Multifunctional and Cross-Reactive T Cells to the Lung.

Influenza A virus infections in marine mammals and terrestrial carnivores.

Influenza A(H5N8) Virus Similar to Strain in Korea Causing Highly Pathogenic Avian Influenza in Germany

Insights into genetic diversity and biological propensities of potentially zoonotic avian influenza H9N2 viruses circulating in Egypt

Intertypic differentiation and detection of intratypic variants among canine and phocid morbillivirus isolates by kinetic neutralization using a novel immunoplaque assay

Introduction and enzootic of A/H5N1 in Egypt: Virus evolution, pathogenicity and vaccine efficacy ten years on.

Investigations on course and outcome of phocine distemper virus infection in harbour seals (Phoca vitulina) exposed to polychlorinated biphenyls. Virological and serological investigations

Isolation and genetic characterization of a novel 2.2.1.2a H5N1 virus from a vaccinated meat-turkeys flock in Egypt

Limited susceptibility of chickens, turkeys, and mice to pandemic (H1N1) 2009 virus

Minute excretion of highly pathogenic avian influenza virus A/chicken/Indonesia/2003 (H5N1) from experimentally infected domestic pigeons (Columbia livia) and lack of transmission to sentinel chickens

Molecular characterization and baculovirus expression of the glycoprotein B of a seal herpesvirus (phocid herpesvirus-1).

Molecular subtyping of European swine influenza viruses and scaling to high-throughput analysis.

Morbillivirus antibodies of maternal origin in harbour seal pups. (Phoca vitulina)

Multiple dose vaccination with heterologous H5N2 vaccine: immune response and protection against variant clade 2.2.1 highly pathogenic avian influenza H5N1 in broiler breeder chickens

Multiple introductions of reassorted highly pathogenic avian influenza viruses (H5N8) clade 2.3.4.4b causing outbreaks in wild birds and poultry in Egypt.

Natural Reassortants of Potentially Zoonotic Avian Influenza Viruses H5N1 and H9N2 from Egypt Display Distinct Pathogenic Phenotypes in Experimentally Infected Chickens and Ferrets

New LightCycler PCR for rapid and sensitive quantification of parvovirus B19 DNA guides therapeutic decision-making in relapsing infections

New real time and conventional RT-PCRs for updated molecular diagnosis of infectious bronchitis virus infection (IBV) in chickens in Egypt associated with frequent co-infections with avian influenza and Newcastle Disease viruses

New real-time reverse transcriptase polymerase chain reactions facilitate detection and differentiation of novel A/H1N1 influenza virus in porcine and human samples

No virological evidence for an influenza A - like virus in European bats

Novel real-time PCR-based patho- and phylotyping of potentially zoonotic avian influenza A subtype H5 viruses at risk of incursion into Europe in 2017.

Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus.

Outbreaks of highly pathogenic avian influenza H5N1 clade 2.3.2.1c in hunting falcons and kept wild birds in Dubai implicate intercontinental virus spread

Pathology of natural infections by H5N1 highly pathogenic avian influenza virus in mute (Cygnus olor) and whooper (Cygnus cygnus) swans.

Phocine distemper virus (PDV) seroprevalence as predictor for future outbreaks in harbour seals.

Possible sources and spreading routes of highly pathogenic avian influenza virus subtype H5N1 infections in poultry and wild birds in Central Europe in 2007 inferred through likelihood analyses

Poultry food products--a source of avian influenza virus transmission to humans?

Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial

Purification of phocid herpesvirus type 1 glycoproteins B and D and pilot studies of immunogenicity in mice.

Rapid and sensitive detection of immunoglobulin M (IgM) and IgG antibodies against canine distemper virus by a new recombinant nucleocapsid protein-based enzyme-linked immunosorbent assay.