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List of works by Emad A. Rakha

A CD44⁻/CD24⁺ phenotype is a poor prognostic marker in early invasive breast cancer

scientific article published on 27 November 2011

A case-controlled study of the oncologic safety of fat grafting

scientific article published in May 2015

A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal

article

A critical review why assessment of steroid hormone receptors in breast cancer should be quantitative.

scientific article published on 30 July 2012

A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients.

scientific article

A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer.

scientific article published on 10 September 2011

A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks.

scientific article published on 4 April 2009

ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC.

scientific article

Accuracy of frozen section in the diagnosis of liver mass lesions.

scientific article published on 17 February 2006

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers

scientific article

Altered glutamine metabolism in breast cancer; subtype dependencies and alternative adaptations

scientific article published on 3 August 2017

Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells

scientific article published on 08 March 2017

An approach to the diagnosis of spindle cell lesions of the breast

scientific article

An overview of assessment of prognostic and predictive factors in breast cancer needle core biopsy specimens

scientific article

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation

scientific article

Androgen dependent mechanisms of pro-angiogenic networks in placental and tumor development

scientific article published on 20 February 2017

Are acinic cell carcinomas of the breast and salivary glands distinct diseases?

scientific article published on 16 February 2015

Are triple-negative and basal-like breast cancer synonymous?

scientific article

Are triple-negative tumours and basal-like breast cancer synonymous?

scientific article published in January 2007

Assessment of and rearrangements in breast adenomyoepitheliomas

Association between CD8+ T-cell infiltration and breast cancer survival in 12,439 patients

scientific article published on 9 June 2014

Atypical ductal hyperplasia: update on diagnosis, management, and molecular landscape.

scientific article

Audit of performance of needle core biopsy diagnoses of screen detected breast lesions

scientific article published on 14 July 2008

Authors' reply: Combining two antibodies to define E-cadherin loss of expression in non-lobular breast carcinomas: when less is more

scientific article published in September 2013

BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen Resistant Breast Cancer

scientific article

Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance

scientific article

Basal phenotype: a powerful prognostic factor in small screen-detected invasive breast cancer with long-term follow-up.

scientific article

Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

scientific article

Basal-like breast cancer: a critical review

scientific article published on May 2008

Basal-like breast carcinoma: from expression profiling to routine practice

scientific article published on June 2009

Bimodality of intratumor Ki67 expression is an independent prognostic factor of overall survival in patients with invasive breast carcinoma

scientific article published on 27 January 2016

Biologic and clinical characteristics of breast cancer with single hormone receptor positive phenotype

scientific article published on 17 September 2007

Biological and clinical significance of PARP1 protein expression in breast cancer

scientific article

Breast Neoplasms with Dermal Analogue Differentiation (Mammary Cylindroma): Report of 3 Cases and a Proposal for a New Terminology

scientific article published on 31 August 2015

Breast cancer histologic grading using digital microscopy: concordance and outcome association

scientific article published on 13 March 2018

Breast cancer intra-tumour heterogeneity: Current status and clinical implications

scientific article published on 2 May 2018

Breast cancer prognostic classification in the molecular era: the role of histological grade

scientific article

Breast cancer: updated guideline recommendations for HER2 testing.

scientific article

Breast carcinoma with basal differentiation: a proposal for pathology definition based on basal cytokeratin expression.

scientific article

Breast carcinoma with basal phenotype: mammographic findings

scientific article published on August 2008

Breast conservation in ductal carcinoma in situ (DCIS): what defines optimal margins?

scientific article published on 7 November 2016

Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management

scientific article

Breast pathology today: morphology and molecules

scientific article published in June 2013

Brief Fixation and Hormone Receptor Expression in Breast Cancer

scientific article published on 01 March 2015

C-Met in invasive breast cancer: is there a relationship with the basal-like subtype?

scientific article

Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival

scientific article published on 31 October 2016

Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype.

scientific article published on 8 July 2008

Cell Proliferation (KI-67) Expression Is Associated with Poorer Prognosis in Nigerian Compared to British Breast Cancer Women

scientific article published on 11 April 2013

Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay

scientific article

Characteristics of basal cytokeratin expression in breast cancer

scientific article published on 16 April 2013

Characterization and outcome of breast needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening

scientific article published on 11 February 2011

Checkpoint Kinase 1 Expression Predicts Poor Prognosis in Nigerian Breast Cancer Patients

scientific article

Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response

scientific article published on 17 February 2015

Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma

scientific article

Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer

scientific article published on 3 October 2015

Chromosome 16 tumor-suppressor genes in breast cancer

scientific article

Clinical Impact of Tumor DNA Repair Expression and T-cell Infiltration in Breast Cancers

scientific article published on 2 March 2017

Clinical and biological roles of Kelch-like family member 7 in breast cancer: a marker of poor prognosis

scientific article published on 9 April 2018

Clinical and biological significance of E-cadherin protein expression in invasive lobular carcinoma of the breast

scientific article published in October 2010

Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein

scientific article

Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer

scientific article

Clinical outcome of atypical endometrial hyperplasia diagnosed on an endometrial biopsy: institutional experience and review of literature.

scientific article

Clinical utility of reverse phase protein array for molecular classification of breast cancer

scientific article published on 09 December 2015

Clinicopathologic and molecular predictors of axillary lymph node metastasis in early-stage breast cancer: a mathematical predictive model.

scientific article

Clinicopathologic and molecular significance of phospho-Akt expression in early invasive breast cancer

scientific article published on 9 July 2010

Clinicopathological and Functional Significance of RECQL1 Helicase in Sporadic Breast Cancers

scientific article published on 11 November 2016

Clinicopathological and molecular characteristics of Ku 70/80 expression in Nigerian breast cancer and its potential therapeutic implications

scientific article

Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women

scientific article published on 8 October 2013

Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers.

scientific article

Clinicopathological and prognostic significance of Ras association and pleckstrin homology domains 1 (RAPH1) in breast cancer

scientific article published on 28 July 2018

Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers

scientific article published on 3 September 2016

Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts.

scientific article

Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer

scientific article published on 28 April 2013

Combinatorial biomarker expression in breast cancer

scientific article published on 28 January 2010

Construction of tissue microarrays from core needle biopsies - a systematic literature review

scientific article published on 12 August 2015

Correlations of morphological features and surgical management to clinical outcome in a multicentre study of 241 phyllodes tumours of the breast

scientific article published on 16 December 2020

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Current issues with luminal subtype classification in terms of prediction of benefit from endocrine therapy in early breast cancer

scientific article published on 30 March 2018

Current topics in breast pathology: expert perspectives

scientific article published on 6 January 2017

Current trials to reduce surgical intervention in ductal carcinoma in situ of the breast: Critical review.

scientific article published on 22 July 2017

Cytological assessment of conventional transbronchial fine needle aspiration of lymph nodes

scientific article published on 18 August 2009

Cytoplasmic localization of alteration/deficiency in activation 3 (ADA3) predicts poor clinical outcome in breast cancer patients

scientific article published on 4 January 2013

DNA damage repair in breast cancer and its therapeutic implications

scientific article published on 26 December 2016

DNA damage response markers are differentially expressed in BRCA-mutated breast cancers

scientific article

DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers

scientific article

Diagnostic challenges in papillary lesions of the breast

scientific article published on 24 November 2017

Diagnostic concordance of breast pathologists: lessons from the National Health Service Breast Screening Programme Pathology External Quality Assurance Scheme

scientific article published on 4 November 2016

Diagnostic concordance of reporting lymphovascular invasion in breast cancer

scientific article

Do primary mammary osteosarcoma and chondrosarcoma exist? A review of a large multi-institutional series of malignant matrix-producing breast tumours

scientific article published on 22 October 2012

E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance

scientific article published in June 2005

ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer

scientific article published on 2 August 2014

Efficacy of an incident-reporting system in cellular pathology: a practical experience

scientific article published on 24 March 2012

Eighth Edition Cancer Staging Manual of Breast Cancer by the American Joint Committee on Cancer: are the new changes to improve staging or a treatment decision tool?

scientific article published on 26 July 2018

Encapsulated Papillary Carcinoma of the Breast

scientific article published on 01 August 2011

Encapsulated papillary carcinoma of the breast: a study of invasion associated markers

scientific article published on 3 May 2012

EpCAM expression is an indicator of recurrence in basal-like breast cancer

scientific article

Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study

scientific article published on 26 April 2014

Erratum to: Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer.

scientific article published on 22 July 2016

Estrogen receptor-negative breast carcinomas: a review of morphology and immunophenotypical analysis

scientific article published in January 2005

Evaluation of touch preparation cytology during frozen-section diagnoses of pulmonary lesions.

scientific article published on 30 June 2010

Expression of BRCA1 protein in breast cancer and its prognostic significance

scientific article

Expression of CDK7, Cyclin H, and MAT1 Is Elevated in Breast Cancer and Is Prognostic in Estrogen Receptor-Positive Breast Cancer

scientific article published on 14 June 2016

Expression of E2F-4 in invasive breast carcinomas is associated with poor prognosis

scientific article published in July 2004

Expression of mucins (MUC1, MUC2, MUC3, MUC4, MUC5AC and MUC6) and their prognostic significance in human breast cancer

scientific article

Expression of the transcription factor CTCF in invasive breast cancer: a candidate gene located at 16q22.1.

scientific article published on October 2004

Expression profiling technology: its contribution to our understanding of breast cancer

scientific article published on January 2008

FKBPL: a marker of good prognosis in breast cancer

scientific article published in May 2015

FOXO3a nuclear localisation is associated with good prognosis in luminal-like breast cancer

scientific article published on 19 February 2011

Fatty acid binding protein 7 expression and its sub-cellular localization in breast cancer

scientific article

First international TNBC conference meeting report

scientific article published on 8 February 2018

Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance.

scientific article published on 4 June 2008

Further evidence that E-cadherin is not a tumour suppressor gene in invasive ductal carcinoma of the breast: an immunohistochemical study

scientific article published on 24 January 2013

Further evidence to support bimodality of oestrogen receptor expression in breast cancer

scientific article

Genetic analysis of microglandular adenosis and acinic cell carcinomas of the breast provides evidence for the existence of a low-grade triple-negative breast neoplasia family

scientific article published on 07 October 2016

Gigantic recurrent abdominal desmoid tumour: a case report

scientific article published on 06 December 2006

Global histone modifications in breast cancer and their prognostic significance.

scientific article published in November 2006

Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.

scientific article published on 14 April 2009

Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer

scientific article published in April 2010

HER2/HER3 heterodimers and p21 expression are capable of predicting adjuvant trastuzumab response in HER2+ breast cancer

scientific article published on 06 April 2014

Heterogeneity of tumour-infiltrating lymphocytes in breast cancer and its prognostic significance

scientific article published on 09 October 2018

High nuclear MSK1 is associated with longer survival in breast cancer patients

scientific article

High-grade encapsulated papillary carcinoma of the breast: an under-recognized entity

scientific article

High-resolution analysis of 16q22.1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry

scientific article

High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses

scientific article published on September 2005

Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast

scientific article published on 11 October 2007

Histological features of medullary carcinoma and prognosis in triple-negative basal-like carcinomas of the breast

scientific article published on 25 June 2010

Histological grade of invasive carcinoma of the breast assessed on needle core biopsy - modifications to mitotic count assessment to improve agreement with surgical specimens

scientific article published on 10 September 2011

Histological grading of breast cancer on needle core biopsy: the role of immunohistochemical assessment of proliferation

scientific article published on August 2010

Human epidermal growth factor receptor 2 testing in invasive breast cancer: should histological grade, type and oestrogen receptor status influence the decision to repeat testing?

scientific article

IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients

scientific article published on 18 December 2017

Identification and definition of novel clinical phenotypes of breast cancer through consensus derived from automated clustering methods.

scientific article published on 13 May 2008

Identification of key clinical phenotypes of breast cancer using a reduced panel of protein biomarkers

scientific article published on 05 September 2013

Imaging overview of metaplastic carcinomas of the breast: a large study of 71 cases.

scientific article published on June 2016

Immune Infiltration in Invasive Lobular Breast Cancer

scientific article published on 20 February 2018

Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas).

scientific article published on August 2008

Immunoprofile of metaplastic carcinomas of the breast.

scientific article published on 28 December 2016

Impact of basal-like breast carcinoma determination for a more specific therapy

scientific article published on 10 June 2008

Impact of breast cancer grade discordance on prediction of outcome

scientific article published on 19 September 2018

Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer.

scientific article published on 5 July 2016

In Reply

Inclusion of KI67 significantly improves performance of the PREDICT prognostication and prediction model for early breast cancer

scientific article

Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile

scientific article published on 24 October 2015

Infiltrative epitheliosis of the breast

scientific article published on 29 March 2012

Inflammatory breast cancer: time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research

scientific article published on 31 March 2015

Influence of E-cadherin expression on the mammographic appearance of invasive nonlobular breast carcinoma detected at screening

scientific article published on 31 July 2009

Inhibition of HER2 Increases JAGGED1-dependent Breast Cancer Stem Cells: Role for Membrane JAGGED1

Integrating breast cancer genetics into clinical practice.

scientific article published on January 2012

Intra-operative Assessment of Excision margins During Breast Conserving Surgery by Integrated Raman Microscopy and Auto-fluorescence Imaging

Intra-operative spectroscopic assessment of surgical margins during breast conserving surgery.

scientific article published on 9 July 2018

Invasion in breast lesions: the role of the epithelial-stroma barrier

scientific article published on 2 December 2017

Invasive Lobular Carcinoma Mimicking Papillary Carcinoma: A Report of Three Cases

scientific article

Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes

scientific article published on 26 November 2007

Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification

scientific article

Involvement of metformin and AMPK in the radioresponse and prognosis of luminal versus basal-like breast cancer treated with radiotherapy

scientific article

KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer

scientific article

Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections

scientific article

Lack of expression of the proteins GMPR2 and PPARα are associated with the basal phenotype and patient outcome in breast cancer.

scientific article

Lobular breast carcinoma and its variants

scientific article published on February 2010

Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry

scientific article published on July 2013

Loss of Dicer expression is associated with breast cancer progression and recurrence

scientific article published on 21 July 2012

Loss of expression of chromosome 16q genes DPEP1 and CTCF in lobular carcinoma in situ of the breast

scientific article published on 23 January 2008

Loss of the nuclear pool of ubiquitin ligase CHIP/STUB1 in breast cancer unleashes the MZF1-cathepsin pro-oncogenic program.

scientific article published on 6 March 2018

Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors

scientific article published in Nature Communications

Low calpain-9 is associated with adverse disease-specific survival following endocrine therapy in breast cancer

scientific article

Low expression of G protein-coupled oestrogen receptor 1 (GPER) is associated with adverse survival of breast cancer patients.

scientific article published on 25 May 2018

Low–Estrogen Receptor–Positive Breast Cancer: The Impact of Tissue Sampling, Choice of Antibody, and Molecular Subtyping

scientific article published on 02 July 2012

Lymph-node metastases in invasive lobular carcinoma are different from those in ductal carcinoma of the breast

scientific article published on 28 June 2011

Lymphatic and blood vessels in basal and triple-negative breast cancers: characteristics and prognostic significance

scientific article published on 4 March 2011

MIB1/Ki-67 labelling index can classify grade 2 breast cancer into two clinically distinct subgroups

scientific article published on 11 July 2010

MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.

scientific article published on 08 March 2016

MYC regulation of glutamine-proline regulatory axis is key in luminal B breast cancer

scientific article published on 23 November 2017

Macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment: review of pathological issues and suggested approaches.

scientific article

Markers of progression in early-stage invasive breast cancer: a predictive immunohistochemical panel algorithm for distant recurrence risk stratification.

scientific article published on 8 May 2015

Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes

scientific article published on 28 March 2018

Metaplastic breast carcinoma: tumour histogenesis or dedifferentiation?

scientific article published on April 2011

Metastatic triple-negative breast cancer

scientific article published on 23 April 2011

Microglandular adenosis associated with triple-negative breast cancer is a neoplastic lesion of triple-negative phenotype harbouring TP53 somatic mutations

scientific article published on 25 January 2016

Modern classification of breast cancer: should we stick with morphology or convert to molecular profile characteristics

scientific article published on July 2011

Molecular Mechanisms Underlying Lymphovascular Invasion in Invasive Breast Cancer

scientific article published on 31 August 2015

Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women

scientific article

Molecular classification of breast cancer: what the pathologist needs to know

scientific article published on 28 December 2016

Molecular profiling of breast cancer in Nigerian women identifies an altered p53 pathway as a major mechanism underlying its poor prognosis compared with British counterpart

scientific article published on April 2014

Morphogenesis of the papillary lesions of the breast: phenotypic observation

scientific article published on 06 August 2015

Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation.

scientific article published on March 2006

National guidelines and level of evidence: comments on some of the new recommendations in the American Society of Clinical Oncology and the College of American Pathologists human epidermal growth factor receptor 2 guidelines for breast cancer

scientific article published on 9 March 2015

Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer.

scientific article published on 11 March 2014

Nottingham Prognostic Index Plus: Validation of a clinical decision making tool in breast cancer in an independent series

scientific article published on 15 January 2016

Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer.

scientific article published on 26 April 2016

Novel immunohistochemistry-based signatures to predict metastatic site of triple-negative breast cancers

scientific article

Outcome of breast lesions diagnosed as lesion of uncertain malignant potential (B3) or suspicious of malignancy (B4) on needle core biopsy, including detailed review of epithelial atypia

scientific article published on 03 March 2011

Outcome of pure mucocele-like lesions diagnosed on breast core biopsy

scientific article published on 12 February 2013

Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance

scientific article published on 20 June 2016

Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients

scientific article

PIASγ expression in relation to clinicopathological, tumour factors and survival in indigenous black breast cancer women

scientific article published on 29 October 2013

PIK3CA expression in invasive breast cancer: a biomarker of poor prognosis

scientific article published on 22 August 2009

PREDICT Plus: development and validation of a prognostic model for early breast cancer that includes HER2.

scientific article

Panoptic Overview of Triple-Negative Breast Cancer in Nigeria: Current Challenges and Promising Global Initiatives

scientific article published on 01 July 2018

Papillary carcinoma of the breast: diagnostic agreement and management implications

scientific article

Patho-biological aspects of basal-like breast cancer

scientific article published on 09 March 2008

Phenotypic characterisation of breast cancer: the role of CDC42.

scientific article published on 27 April 2017

Phyllodes tumours of the breast: a consensus review

scientific article

Pitfalls in outcome prediction of breast cancer.

scientific article published on 25 April 2013

Pleomorphic adenoma-like tumour of the breast

scientific article published on 10 June 2015

Pleomorphic lobular carcinoma of the breast: is it a prognostically significant pathological subtype independent of histological grade?

scientific article published on 14 December 2012

Portal inflammation is associated with advanced histological changes in alcoholic and non-alcoholic fatty liver disease

scientific article published on September 2010

Predictive value of needle core biopsy diagnoses of lesions of uncertain malignant potential (B3) in abnormalities detected by mammographic screening

scientific article published on 01 December 2008

Prognostic Significance of Nottingham Histologic Grade in Invasive Breast Carcinoma

scientific article published on 19 May 2008

Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer.

scientific article published on 21 March 2015

Prognostic and biological significance of proliferation and HER2 expression in the luminal class of breast cancer

scientific article published on 18 April 2014

Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study

scientific article published on 25 November 2014

Prognostic markers in triple-negative breast cancer

scientific article

Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis

scientific article

Prognostic significance of nucleolar assessment in invasive breast cancer

scientific article published on 17 November 2019

Prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome.

scientific article published on 13 May 2008

Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast.

scientific article published on 20 March 2018

Prognostic significance of tumour infiltrating B lymphocytes in breast ductal carcinoma in situ.

scientific article

Prognostic stratification of oestrogen receptor-positive HER2-negative lymph node-negative class of breast cancer.

scientific article published on 26 October 2016

Prognostic value of proliferation assay in the luminal, HER2-positive, and triple-negative biologic classes of breast cancer

scientific article

RECQL4 helicase has oncogenic potential in sporadic breast cancers

scientific article published on 22 December 2015

RERG (Ras-like, oestrogen-regulated, growth-inhibitor) expression in breast cancer: a marker of ER-positive luminal-like subtype.

scientific article published on 10 August 2010

Re-audit of revised method for assessing the mitotic component of histological grade in needle core biopsies of invasive carcinoma of the breast

scientific article published on 02 March 2012

Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas.

scientific article published on 8 May 2018

Refining the definition of HER2 low class in invasive breast cancer

scientific article published in 2022

Reply to Rosen

scientific article

Review of the national external quality assessment (EQA) scheme for breast pathology in the UK.

scientific article

Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer

scientific article

Routine elastic staining assists detection of vascular invasion in colorectal cancer

scientific article published on 01 November 2006

SUMOylation proteins in breast cancer

scientific article published on March 2014

Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion

Screen-detected breast lesions with malignant needle core biopsy diagnoses and no malignancy identified in subsequent surgical excision specimens (potential false-positive diagnosis).

scientific article published on 02 January 2009

Screen-detected malignant breast lesions diagnosed following benign (B2) or normal (B1) needle core biopsy diagnoses

scientific article published on 12 April 2010

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

scientific article

Solid Papillary Breast Carcinomas Resembling the Tall Cell Variant of Papillary Thyroid Neoplasms (Solid Papillary Carcinomas with Reverse Polarity) Harbor Recurrent Mutations Affecting IDH2 and PIK3CA: A Validation Cohort

scientific article published on 30 March 2018

Sonographic correlations with the new molecular classification of invasive breast cancer.

scientific article published on 14 May 2009

Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators.

scientific article published on 30 July 2015

Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

scientific article

Surgical management of ductal carcinoma in situ of the breast: A large retrospective study from a single institution

scientific article published on 18 July 2019

TOMM34 expression in early invasive breast cancer: a biomarker associated with poor outcome

scientific article published on 4 October 2012

Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy

scientific article published on 27 August 2014

Targeting XRCC1 deficiency in breast cancer for personalized therapy.

scientific article published on 19 December 2012

Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy

scientific article

The Spectrum of Triple-Negative Breast Disease: High- and Low-Grade Lesions

scientific article

The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours

scientific article published on 22 March 2018

The biological and clinical characteristics of breast carcinoma with mixed ductal and lobular morphology

scientific article published on 11 April 2008

The expression of ERalpha, ERbeta and PR in lobular carcinoma in situ of the breast determined using laser microdissection and real-time PCR.

scientific article

The impact of using defined criteria for adequacy of fine needle aspiration cytology of the thyroid in routine practice.

scientific article published on February 2011

The influence of basal phenotype on the metastatic pattern of breast cancer.

scientific article

The mammalian target of rapamycin complex 1 (mTORC1) in breast cancer: the impact of oestrogen receptor and HER2 pathways

scientific article

The mammographic correlations of a new immunohistochemical classification of invasive breast cancer

scientific article published on 21 August 2008

The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients

scientific article published on 6 December 2012

The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes

scientific article published on 16 March 2018

The oestrogen receptor coactivator CARM1 has an oncogenic effect and is associated with poor prognosis in breast cancer

scientific article published on 26 July 2013

The p53 positive Bcl-2 negative phenotype is an independent marker of prognosis in breast cancer

scientific article published on 01 March 2007

The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancer

scientific article

The prognostic significance of PELP1 expression in invasive breast cancer with emphasis on the ER-positive luminal-like subtype

scientific article (publication date: April 2010)

The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts

scientific article

The prognostic significance of early stage lymph node positivity in operable invasive breast carcinoma: number or stage

scientific article published on 20 April 2012

The prognostic significance of inflammation and medullary histological type in invasive carcinoma of the breast

scientific article published on 14 March 2009

The prognostic significance of lymphovascular invasion in invasive breast carcinoma

scientific article published on 16 December 2011

The prognostic significance of steroid receptor co-regulators in breast cancer: co-repressor NCOR2/SMRT is an independent indicator of poor outcome

scientific article published on 28 September 2007

The proteins FABP7 and OATP2 are associated with the basal phenotype and patient outcome in human breast cancer.

scientific article published on 10 July 2009

The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response

scientific article published on 29 June 2018

The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study

scientific article published on 23 May 2015

The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

The sensitivity of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma.

scientific article published on December 2010

The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis

scientific article

The updated ASCO/CAP guideline recommendations for HER2 testing in the management of invasive breast cancer: a critical review of their implications for routine practice

scientific article published on 31 January 2014

The value of examination of multiple levels of mammary needle core biopsy specimens taken for investigation of lesions other than calcification

scientific article published on 22 August 2012

Thioredoxin-interacting protein is an independent risk stratifier for breast ductal carcinoma in situ

scientific article published on 28 June 2018

Three dimensional reconstruction of a human breast carcinoma using routine laboratory equipment and immunohistochemistry.

scientific article published in September 2005

Three-dimensional reconstruction of sentinel lymph nodes with metastatic breast cancer indicates three distinct patterns of tumour growth

scientific article

Too many statistical errors for meaningful interpretation. Response to letter to the editor

scientific article published in April 2013

Topo2α protein expression predicts response to anthracycline combination neo-adjuvant chemotherapy in locally advanced primary breast cancer

scientific article

Towards intra-operative diagnosis of tumours during breast conserving surgery by selective-sampling Raman micro-spectroscopy

scientific article

Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.

scientific article

Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.

scientific article

Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes

scientific article published on 24 March 2009

Triple-negative/basal-like breast cancer: review

scientific article published on January 2009

Tubular carcinoma of the breast: further evidence to support its excellent prognosis

scientific article published on 16 November 2009

Tumor size is an unreliable predictor of prognosis in basal-like breast cancers and does not correlate closely with lymph node status

scientific article published on 4 July 2008

Tumour Heterogeneity of Breast Cancer: From Morphology to Personalised Medicine

scientific article published on 10 February 2018

Tumour cell membrane laminin expression is associated with basal-like phenotype and poor survival in Nigerian breast cancer

scientific article published on August 2016

Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer

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Updated UK Recommendations for HER2 assessment in breast cancer

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Vacuum-assisted excision of breast lesions of uncertain malignant potential (B3) – an alternative to surgery in selected cases

scientific article published on 01 October 2008

Viewpoint: Availability of oestrogen receptor and HER2 status for the breast multidisciplinary meeting discussion; time to get it right.

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Will MRI screening deliver the expected survival advantage in BRCA 1 carriers?

scientific article published on November 2009