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List of works by Keiichi I Nakayama

A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients

scientific article published on 26 July 2019

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis

scientific article published on 15 September 2020

A ubiquitin-like protein encoded by the "noncoding" RNA TINCR promotes keratinocyte proliferation and wound healing

scientific article published on 05 August 2021

Artificial intelligence in oncology

scientific article published on 04 March 2020

Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

scientific article published on 23 November 2020

Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons

scientific article published on 01 July 2021

Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.

scientific article published on 11 April 2010

Disruption of FBXL5-mediated cellular iron homeostasis promotes liver carcinogenesis

scientific article published on 15 March 2019

Drug repositioning in cancer: The current situation in Japan

scientific article published on 11 February 2020

Erratum: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

scientific article published in Nature

F-Box Proteins and Cancer

scientific article published on 15 May 2020

Kastor and Polluks polypeptides encoded by a single gene locus cooperatively regulate VDAC and spermatogenesis

scientific article published on 28 February 2022

Loss of Fbxw7 impairs development of and induces heterogeneous tumor formation in the mouse mammary gland

scientific article published on 24 November 2020

Negative feedback loop in the Bim-caspase-3 axis regulating apoptosis and activity of osteoclasts.

scientific article

Nuclear-cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXK1.

scientific article

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

scientific article

Potentials of C-C motif chemokine 2-C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents

scientific article published on 10 June 2019

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation

scientific article published on 11 September 2020

Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

scientific article published on 10 November 2020

Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data

scientific article published on 16 December 2018

Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and Caspase-3.

scientific article published in January 2010

SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation

scientific article published on 20 March 2019

Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

scientific article

Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium

scientific article published on 21 March 2022

TMEM55B contributes to lysosomal homeostasis and amino acid-induced mTORC1 activation.

scientific article published on 11 April 2018

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

scientific article published on 08 November 2012

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

scientific article

Trans-omic analysis reveals obesity-associated dysregulation of inter-organ metabolic cycles between the liver and skeletal muscle

scientific article published in 2021

Transomics analysis reveals allosteric and gene regulation axes for altered hepatic glucose-responsive metabolism in obesity

scientific article published on 01 December 2020

mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

scientific journal article