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List of works by Christine A Wells

A comprehensive transcript map of the mouse Gnas imprinted complex

scientific article

A cross-study transcriptional analysis of Parkinson's disease

scientific article

A molecular classification of human mesenchymal stromal cells

scientific article published on 24 March 2016

A promoter-level mammalian expression atlas

scientific article

A simple, scalable approach to building a cross-platform transcriptome atlas

scientific article published on 28 September 2020

Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias

scientific article published in Nature Communications

Alternate transcription of the Toll-like receptor signaling cascade

scientific article published on 17 February 2006

An Inflammatory Role for the Mammalian Carboxypeptidase Inhibitor Latexin: Relationship to Cystatins and the Tumor Suppressor TIG1

scientific article

An atlas of human long non-coding RNAs with accurate 5' ends.

scientific article

An atypical role for the myeloid receptor Mincle in central nervous system injury

scientific article

An integrated expression atlas of miRNAs and their promoters in human and mouse.

scientific article

Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

scientific article

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs

scientific article (publication date: 5 December 2002)

Characterization of Phenotypic and Transcriptional Differences in Human Pluripotent Stem Cells under 2D and 3D Culture Conditions

scientific article published on 24 October 2016

Chondroprotection, myth or reality: an experimental approach

scientific article published on 01 February 1990

Colony-stimulating factor-1 promotes kidney growth and repair via alteration of macrophage responses

scientific article

Complex Loci in human and mouse genomes

scientific article

Concise Review: New Paradigms for Down Syndrome Research Using Induced Pluripotent Stem Cells: Tackling Complex Human Genetic Disease

scientific article published on February 14, 2013

Concordant epigenetic silencing of transforming growth factor-beta signaling pathway genes occurs early in breast carcinogenesis.

scientific article published on December 2007

Continued discovery of transcriptional units expressed in cells of the mouse mononuclear phagocyte lineage

scientific article published in June 2003

Corrigendum: Genome-wide analysis of mammalian promoter architecture and evolution

scholarly article published in Nature Genetics

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate

scientific article

Defining an informativeness metric for clustering gene expression data

scientific article published on February 16, 2011

Designer macrophages: Pitfalls and opportunities for modelling macrophage phenotypes from pluripotent stem cells

scientific article published on 16 October 2018

Disease-specific, neurosphere-derived cells as models for brain disorders

scientific article published on 10 August 2010

Divergent reprogramming routes lead to alternative stem-cell states

scientific article

Dynamic Interplay of Innate and Adaptive Immunity During Sterile Retinal Inflammation: Insights From the Transcriptome

scientific article published on 18 July 2018

Erratum: Corrigendum: Divergent reprogramming routes lead to alternative stem-cell states

scientific article published in Nature

Erratum: Corrigendum: Genome-wide characterization of the routes to pluripotency

scientific article published in Nature

Erythrocyte metabolism in potoroid, macropodid and vombatid marsupials.

scientific article

Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidis.

scientific article published on 13 March 2018

FANTOM5 CAGE profiles of human and mouse samples

scientific article published on 29 August 2017

Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.

scientific article published on August 2017

Gene expression variability as a unifying element of the pluripotency network

scientific article

Generation of diversity in the innate immune system: macrophage heterogeneity arises from gene-autonomous transcriptional probability of individual inducible genes

scientific article

Genetic control of the innate immune response

scientific article

Genome-wide analysis of mammalian promoter architecture and evolution

scientific article (publication date: June 2006)

Genome-wide characterization of the routes to pluripotency.

scientific article published on December 2014

Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE.

scientific article

Genome-wide review of transcriptional complexity in mouse protein kinases and phosphatases.

scientific article

Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP.

scientific article published on 17 May 2018

High incidence of contaminating maternal cell overgrowth in human placental mesenchymal stem/stromal cell cultures: a systematic review

scientific article

Human CD141+ Dendritic Cell and CD1c+ Dendritic Cell Undergo Concordant Early Genetic Programming after Activation in Humanized Mice In Vivo

scientific article published on 30 October 2017

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli.

scientific article published in June 2012

Human iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks.

scientific article published on 13 October 2017

Human mesenchymal stem cells alter the gene profile of monocytes from patients with Type 2 diabetes and end-stage renal disease.

scientific article

IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection

scientific article published on January 1, 2011

Identification of generic and pathogen-specific cord blood monocyte transcriptomes reveals a largely conserved response in preterm and term newborn infants.

scientific article

Identification of unsafe human induced pluripotent stem cell lines using a robust surrogate assay for pluripotency

scientific article published on August 2013

Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.

scientific article published on July 2000

Imprinting of distal mouse chromosome 2 is associated with phenotypic anomalies in utero

scientific article published on 01 December 1998

Induced Pluripotent Stem Cells from Ataxia-Telangiectasia Recapitulate the Cellular Phenotype

scientific article published on June 28, 2012

Induction of Nramp2 in activated mouse macrophages is dissociated from regulation of the Nramp1, classical inflammatory genes, and genes involved in iron metabolism.

scientific article

Inflammation suppressor genes: please switch out all the lights

scientific article

LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action

scientific article

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A infection

article published in the Proceedings of the National Academy of Sciences of the United States of America

Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia

scientific article (publication date: 31 December 2010)

Mesenchymal Stromal Cells are Readily Recoverable from Lung Tissue, but not the Alveolar Space, in Healthy Humans

scientific article published on 29 June 2016

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia

scientific journal article

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye.

scientific article published on 26 February 2016

Mincle polarizes human monocyte and neutrophil responses to Candida albicans.

scientific article

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

scientific article published on 06 January 2020

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern

scientific article

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish.

scientific article published on May 2017

NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease

scientific article

Peripheral blood monocyte gene expression profile clinically stratifies patients with recent-onset type 1 diabetes.

scientific article published on 8 March 2012

Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure

scientific article published on July 11, 2011

Pilot studies on the parallel production of soluble mouse proteins in a bacterial expression system.

scientific article

Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development.

scientific article published in June 2000

Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease.

scientific article published in March 2018

Signal transduction by the growth hormone receptor.

scientific article published on July 1994

Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed states of human pluripotent stem cells.

scientific article

Small RNA changes en route to distinct cellular states of induced pluripotency.

scientific article published on 10 December 2014

Stemformatics: visualisation and sharing of stem cell gene expression.

scientific article published on 20 December 2012

Stemformatics: visualize and download curated stem cell data

scientific article published on 01 January 2019

Systems biology of transcription control in macrophages

scientific article published on December 2007

TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

scientific article

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia

scientific article

The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons

scientific article published on 31 May 2018

The ground state of innate immune responsiveness is determined at the interface of genetic, epigenetic, and environmental influences

scientific article

The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

scientific journal article

The mononuclear phagocyte system revisited.

scientific article

The role of the WSXWS equivalent motif in growth hormone receptor function.

scientific article

The transcriptional landscape of the mammalian genome

scientific article

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

scientific article

Toll-Like Receptors Drive Specific Patterns of Tolerance and Training on Restimulation of Macrophages.

scientific article

Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

scientific article published on 01 September 2004

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

scientific article

Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs

scientific article

Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor

scientific article

Transcriptional Profiling of Stem Cells: Moving from Descriptive to Predictive Paradigms

scientific article published on 01 August 2019

Transcriptional ontogeny of first trimester human fetal and placental mesenchymal stem cells: Gestational age versus niche

scientific article

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

scientific article published on 15 May 2020

Using a 3D virtual muscle model to link gene expression changes during myogenesis to protein spatial location in muscle

scientific article

Variance of gene expression identifies altered network constraints in neurological disease

scientific article

YuGene: a simple approach to scale gene expression data derived from different platforms for integrated analyses

scientific article

attract: A Method for Identifying Core Pathways That Define Cellular Phenotypes

scientific article published on October 14, 2011

pathVar: a new method for pathway-based interpretation of gene expression variability.

scientific article published on 23 May 2017