List of works - Haigang Ren

Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-X(L) and Bax.

scientific article published on 2 April 2013

Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease

scientific article published on 14 October 2014

Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitro ⬇️

scientific article published on April 8, 2013

DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD

scientific article

DJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo

scientific article published on 24 June 2019

DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells

scientific article published on 26 May 2010

Dendritic cell nuclear protein-1 regulates melatonin biosynthesis by binding to BMAL1 and inhibiting the transcription of N-acetyltransferase in C6 cells.

scientific article published on 7 December 2017

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

scientific article published on 19 April 2011

Familial Parkinson's Disease-Associated L166P Mutant DJ-1 is Cleaved by Mitochondrial Serine Protease Omi/HtrA2.

scientific article published on 24 November 2017

Genomic variants at 20p11 associated with body fat mass in the European population.

scientific article published on 22 February 2017

Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence.

scientific article

Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia

scientific article (publication date: 2013)

Imbalance of Lysine Acetylation Contributes to the Pathogenesis of Parkinson's Disease

scientific article published on 29 September 2020

Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia

scientific article

L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.

scientific article

Loss of VAPB Regulates Autophagy in a Beclin 1-Dependent Manner

scientific article published on 24 August 2018

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR

scientific article published on 02 July 2019

NGFI-B nuclear orphan receptor Nurr1 interacts with p53 and suppresses its transcriptional activity.

scientific article

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases.

scientific article published on 14 May 2010

Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.

scientific article

P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death and

scientific article published on 05 November 2018

P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo

scientific article

Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells.

scientific article published on 14 September 2015

Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathway

scientific article published on 27 June 2018

Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory

scientific article published on 12 October 2016

Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis

scientific article published on 30 May 2019

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice

scientific article

Regulation of autophagic flux by CHIP.

scientific article published on 28 July 2015

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

scientific article published on 29 August 2020

Sumoylation is critical for DJ-1 to repress p53 transcriptional activity.

scientific article

TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.

scientific article

Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice.

scientific article published on 15 February 2018

List of works by Haigang Ren

Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-X(L) and Bax.

Bcl-2 Decreases the Affinity of SQSTM1/p62 to Poly-Ubiquitin Chains and Suppresses the Aggregation of Misfolded Protein in Neurodegenerative Disease

Bcl-2-dependent upregulation of autophagy by sequestosome 1/p62 in vitro ⬇️

DJ-1 inhibits TRAIL-induced apoptosis by blocking pro-caspase-8 recruitment to FADD

DJ-1 regulates tyrosine hydroxylase expression through CaMKKβ/CaMKIV/CREB1 pathway in vitro and in vivo

DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells

Dendritic cell nuclear protein-1 regulates melatonin biosynthesis by binding to BMAL1 and inhibiting the transcription of N-acetyltransferase in C6 cells.

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

Familial Parkinson's Disease-Associated L166P Mutant DJ-1 is Cleaved by Mitochondrial Serine Protease Omi/HtrA2.

Genomic variants at 20p11 associated with body fat mass in the European population.

Hax-1 is rapidly degraded by the proteasome dependent on its PEST sequence.

Identification of CHIP as a novel causative gene for autosomal recessive cerebellar ataxia

Imbalance of Lysine Acetylation Contributes to the Pathogenesis of Parkinson's Disease

Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia

L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.

Loss of VAPB Regulates Autophagy in a Beclin 1-Dependent Manner

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR

NGFI-B nuclear orphan receptor Nurr1 interacts with p53 and suppresses its transcriptional activity.

Omi/HtrA2 is a positive regulator of autophagy that facilitates the degradation of mutant proteins involved in neurodegenerative diseases.

Oxidized DJ-1 interacts with the mitochondrial protein BCL-XL.

P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death and

P7C3 inhibits GSK3β activation to protect dopaminergic neurons against neurotoxin-induced cell death in vitro and in vivo

Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells.

Pharmacological activation of REV-ERBα represses LPS-induced microglial activation through the NF-κB pathway

Phosphodiesterase 10A inhibition attenuates sleep deprivation-induced deficits in long-term fear memory

Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice

Regulation of autophagic flux by CHIP.

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Sumoylation is critical for DJ-1 to repress p53 transcriptional activity.

TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion.

Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice.