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List of works by Charles S Chung

A comprehensive resequence-analysis of 250 kb region of 8q24.21 in men of African ancestry

scientific article

A genome-wide association study of marginal zone lymphoma shows association to the HLA region

scientific article

A genome-wide association study of prostate cancer in West African men

scientific article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A resequence analysis of genomic loci on chromosomes 1q32.1, 5p15.33, and 13q22.1 associated with pancreatic cancer risk

scientific article published on March 2013

A subset-based approach improves power and interpretation for the combined analysis of genetic association studies of heterogeneous traits

journal article published in 2012

Abstract 4593: Genome-wide association study identifies novel loci associated with osteosarcoma

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Aortic Stiffness and Diastolic Dysfunction in Sprague Dawley Rats Consuming Short-Term Fructose Plus High Salt Diet

scientific article published on 28 September 2020

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations

scientific article published on 26 December 2016

Characterization of large structural genetic mosaicism in human autosome

journal article published in 2015

Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer ⬇️

scientific article published in April 2012

Consequences of increasing heart rate on deceleration time, the velocity-time integral, and E/A

scientific article published on 15 November 2005

Contribution of titin and extracellular matrix to passive pressure and measurement of sarcomere length in the mouse left ventricle.

scientific article

Derivation and left ventricular pressure phase plane based validation of a time dependent isometric crossbridge attachment model

scientific article published in December 2006

Detectable clonal mosaicism and its relationship to aging and cancer

journal article published in 2012

Diabetes and diastolic function: stiffness and relaxation from transmitral flow

scientific article published on 01 December 2005

Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat using 3D cine DENSE Cardiovascular Magnetic Resonance

scientific article published on 04 August 2018

Duration of diastole and its phases as a function of heart rate during supine bicycle exercise

scientific article published on 24 June 2004

Early detection of abnormal left ventricular relaxation in acute myocardial ischemia with a quadratic model. Med Eng Phys 2014;36(September (9)):1101-5 by Morimont et al

scientific article published on 03 June 2015

Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

journal article published in 2016

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

scientific article

Further confirmation of germline glioma risk variant rs78378222 in TP53 and its implication in tumor tissues via integrative analysis of TCGA data

journal article published in 2015

Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia

scientific article published on 29 December 2014

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes

scientific article

Genome-Wide Association Study Identifies Three Common Variants Associated with Serologic Response to Vitamin E Supplementation in Men ⬇️

scientific article published on March 21, 2012

Genome-Wide Association Study to Identify Susceptibility Loci That Modify Radiation-Related Risk for Breast Cancer After Childhood Cancer

scientific article

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

scientific journal article

Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region

scientific article published in October 2014

Genome-wide association study identifies multiple loci associated with bladder cancer risk

scientific article (publication date: March 2014)

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

scientific journal article

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma

scientific article

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

scientific article

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

Genome-wide association study of gastric adenocarcinoma in Asia: a comparison of associations between cardia and non-cardia tumours

scientific article published on 30 June 2015

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

scientific article published on 8 February 2018

Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies

scientific article published on 8 February 2012

Heart Rate Is an Important Consideration for Cardiac Imaging of Diastolic Function

scientific article published on 17 February 2016

How myofilament strain and strain rate lead the dance of the cardiac cycle

scientific article published on 30 January 2019

Identification of a novel susceptibility locus at 13q34 and refinement of the 20p12.2 region as a multi-signal locus associated with bladder cancer risk in individuals of European ancestry

scientific article published on 4 January 2016

Improved imputation of common and uncommon SNPs with a new reference set.

scientific article published on 27 December 2011

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Increased myocardial short-range forces in a rodent model of diabetes reflect elevated content of β myosin heavy chain.

scientific article published on 04 September 2013

Increased myocardial stiffness due to cardiac titin isoform switching in a mouse model of volume overload limits eccentric remodeling

scientific article

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

scientific article

Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

scientific article

Large-scale exploration of gene-gene interactions in prostate cancer using a multistage genome-wide association study

scientific article

Large-scale fine mapping of the HNF1B locus and prostate cancer risk

scientific article

Membrane stabilizer Poloxamer 188 improves yield of primary isolated rat cardiomyocytes without impairing function

scientific article published on 01 February 2020

Meta-analysis identifies four new loci associated with testicular germ cell tumor

scientific article published on 12 May 2013

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

scientific article

Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease

scientific article

Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells. ⬇️

scientific article

Myocardial Fiber Mapping of Rat Hearts, Using Apparent Backscatter, with Histologic Validation

scientific article published on 30 May 2019

Myocardial relaxation is accelerated by fast stretch, not reduced afterload

scientific article published on 10 January 2017

Myocyte contractility can be maintained by storing cells with the myosin ATPase inhibitor 2,3 butanedione monoxime

scientific article published in June 2015

Pressure phase-plane based determination of the onset of left ventricular relaxation

scientific article published on 01 December 2007

Removal of immunoglobulin-like domains from titin's spring segment alters titin splicing in mouse skeletal muscle and causes myopathy

scientific article published on February 2014

SMYD2 glutathionylation contributes to degradation of sarcomeric proteins

scientific article published in Nature Communications

Shortening of Titin's Elastic Tandem Ig Segment Leads to Cardiac Hypertrophy and Diastolic Dysfunction

article published in 2013

Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction

scientific article published on 24 May 2013

Temperature and transmural region influence functional measurements in unloaded left ventricular cardiomyocytes.

scientific article

Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23.

scientific article

The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive disease

scientific article published in October 2014

The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma

scientific article published on 23 November 2011

The kinematic filling efficiency index of the left ventricle: contrasting normal vs. diabetic physiology

scientific article

The link between exercise and titin passive stiffness.

scientific article published on 31 July 2017

The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements.

scientific article published on 5 December 2012

The new sequencer on the block: comparison of Life Technology’s Proton sequencer to an Illumina HiSeq for whole-exome sequencing ⬇️

scientific article published on June 12, 2013

The peak atrioventricular pressure gradient to transmitral flow relation: kinematic model prediction with in vivo validation

scientific article published on 01 August 2004

Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions

scientific article

Titin-actin interaction: PEVK-actin-based viscosity in a large animal

scientific article published on 15 November 2011

Titin-isoform dependence of titin-actin interaction and its regulation by S100A1/Ca2+ in skinned myocardium

scientific article

Transmural heterogeneity of cellular level power output is reduced in human heart failure

scientific article

Tuberculosis infection and lung adenocarcinoma: Mendelian randomization and pathway analysis of genome-wide association study data from never-smoking Asian women

scientific article published on 12 July 2019

Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia

scientific article published in Nature Communications

What global diastolic function is, what it is not, and how to measure it

scientific article

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