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List of works by Penny Moore

4E10-resistant variants in a human immunodeficiency virus type 1 subtype C-infected individual with an anti-membrane-proximal external region-neutralizing antibody response

scientific article

A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.

scientific article

Ability to develop broadly neutralizing HIV-1 antibodies is not restricted by the germline Ig gene repertoire

scientific article published on 30 March 2015

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

scientific article published on 24 June 2009

Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial

scientific article published on 26 November 2020

Author Correction: T cell responses to SARS-CoV-2 spike cross-recognize Omicron

scholarly article

Binding of the mannose-specific lectin, griffithsin, to HIV-1 gp120 exposes the CD4-binding site

scientific article

Broad neutralization of human immunodeficiency virus type 1 mediated by plasma antibodies against the gp41 membrane proximal external region

scientific article published on 19 August 2009

Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge

scientific article published on September 2017

Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design

scientific article published on 24 April 2013

Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope

scientific article published on 5 July 2017

Correction for Anthony et al., "Cooperation between Strain-Specific and Broadly Neutralizing Responses Limited Viral Escape and Prolonged the Exposure of the Broadly Neutralizing Epitope".

scientific article published on 13 April 2018

Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article published on 25 September 2017

Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection

scientific article

Development of broadly neutralizing antibodies in HIV-1 infected elite neutralizers

article

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

scientific article

Differences in HIV type 1 neutralization breadth in 2 geographically distinct cohorts in Africa

scientific article published on 14 November 2014

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection

scientific article published on 29 January 2020

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

scholarly article by Andrew Pollard published in 2021

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

scientific article published on 08 April 2022

Evidence for both Intermittent and Persistent Compartmentalization of HIV-1 in the Female Genital Tract

scientific article published on 01 May 2019

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

scientific article

Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences

scientific article published on 23 December 2008

Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization

scientific article

Frequency, kinetics and determinants of viable SARS-CoV-2 in bioaerosols from ambulatory COVID-19 patients infected with the Beta, Delta or Omicron variants

scientific article published on 5 March 2024

Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates

scientific article

Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies

scientific article published on 16 July 2007

Genotypic and phenotypic characterization of viral isolates from HIV-1 subtype C-infected children with slow and rapid disease progression

scientific article published in May 2006

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

article

HIV broadly neutralizing antibody targets

scientific article

HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes

article

High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination

scientific article published on 18 March 2009

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

article

Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

scientific article

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody

scientific article published on 16 December 2019

In vitro generation of HIV type 1 subtype C isolates resistant to enfuvirtide

scientific article

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.

scientific article

Isolation of a monoclonal antibody that targets the alpha-2 helix of gp120 and represents the initial autologous neutralizing-antibody response in an HIV-1 subtype C-infected individual

scientific article

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

scientific article

Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin

scientific article

Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN.

scientific article published on 15 August 2013

Multiple pathways of escape from HIV broadly cross-neutralizing V2-dependent antibodies

scientific article published on 13 February 2013

N-linked glycan modifications in gp120 of human immunodeficiency virus type 1 subtype C render partial sensitivity to 2G12 antibody neutralization

scientific article

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

scientific article

Neutralization Breadth and Potency of Single-Chain Variable Fragments Derived from Broadly Neutralizing Antibodies Targeting Multiple Epitopes on the HIV-1 Envelope

scientific article published on 06 January 2020

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

scientific article

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

scientific article published in September 2016

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

scientific article

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

scientific article published in February 2022

Omicron infection enhances Delta antibody immunity in vaccinated persons

scientific article published in July 2022

Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies

scientific article published on January 2017

Phenotypic characterization of HIV type 1 isolates from Ghana

scientific article

Polyclonal B cell responses to conserved neutralization epitopes in a subset of HIV-1-infected individuals

scientific article

Positive Selection at Key Residues in the HIV Envelope Distinguishes Broad and Strain-Specific Plasma Neutralizing Antibodies

article

Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop

scientific article

Predicted genotypic resistance to the novel entry inhibitor, BMS-378806, among HIV-1 isolates of subtypes A to G.

scientific article published in November 2004

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

scientific article published on 01 July 2019

Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization

scientific article published on 9 June 2008

SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

scientific article

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

scientific article published in Nature Communications

Size Doesn't Matter: Shorter Antibody Loops Can Infiltrate HIV's Env Apex Defenses

scientific article

Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage

scientific article published on 03 September 2019

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

scientific article published on 24 June 2015

Specificity of the autologous neutralizing antibody response

scientific article

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

scientific article

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

scientific article published on 01 April 2020

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

scientific article published on 31 August 2016

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

scientific article

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

scientific article published in March 2022

The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection

scientific article

The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

scientific article

UCLA1, a synthetic derivative of a gp120 RNA aptamer, inhibits entry of human immunodeficiency virus type 1 subtype C

scientific article

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

article

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies.

scientific article published in October 2014

Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

scientific article

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

scientific article

Virological features associated with the development of broadly neutralizing antibodies to HIV-1

scientific article

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