List of works - Cristiano Alessandri

"New" antigenic targets and methodological approaches for refining laboratory diagnosis of antiphospholipid syndrome

scientific article

A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene

scientific article

A polymorphism upstream MIR1279 gene is associated with pericarditis development in Systemic Lupus Erythematosus and contributes to definition of a genetic risk profile for this complication

scientific article

Acute longitudinal myelitis following Cryptococcus laurentii pneumonia in a patient with systemic lupus erythematosus.

scientific article published on 8 October 2014

Anti-GAPDH Autoantibodies as a Pathogenic Determinant and Potential Biomarker of Neuropsychiatric Diseases

scientific article published on 23 May 2016

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus.

scientific article

Anti-carbamylated protein antibodies in systemic lupus erythematosus patients with articular involvement

scientific article published on January 2017

Anti-carbonic anhydrase II antibodies in systemic sclerosis: association with lung involvement

scientific article published on 01 March 2003

Anti-cyclic citrullinated peptide antibody determination in the synovial fluid of patients with rheumatoid arthritis: comment on the article by Caspi et al

scientific article published on 01 August 2006

Anti-endothelial antibodies and neuropsychiatric systemic lupus erythematosus

scientific article published in June 2006

Anti-lysobisphosphatidic acid antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus

scientific article published on 01 April 2005

Antibodies to age-β2 glycoprotein I in patients with anti-phospholipid antibody syndrome.

scientific article published on 24 December 2015

Anti–β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid rafts

scientific article published on 01 August 2007

Assessment of disease activity in Systemic Lupus Erythematosus: Lights and shadows

scientific article

Association between Staphylococcus aureus nasal carriage and disease phenotype in patients affected by systemic lupus erythematosus

scientific article published on 30 July 2016

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients.

scientific article

Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes

scientific article published on 24 January 2015

Autoantibodies specific to a peptide of β2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes

scientific article published on 29 August 2012

Autoantibodies to estrogen receptor α interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus

scientific article published on 01 March 2012

Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis

scientific article

Autoantibody production in anti-TNF-alpha-treated patients

scientific article published on September 2007

Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies.

scientific article published on 12 April 2016

Autophagy occurs in lymphocytes infiltrating Sjögren's syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

scientific article published on 13 October 2020

Avidity of anti-β2-glycoprotein I antibodies in patients with antiphospholipid syndrome

scientific article published on 01 June 2012

Beta2-glycoprotein I is a target of T cell reactivity in patients with advanced carotid atherosclerotic plaques

scientific article published on 01 January 2010

Biological therapies in rheumatic diseases

scientific article published on September 2013

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity

scientific article

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.

scientific article

Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes

scientific article

Clinical relevance of silent red blood cell autoantibodies

scientific article published on 21 September 2017

Determination of antibodies to extractable nuclear antigens by commercial kits: a multicenter study.

scientific article published in January 1998

Distribution of interleukin-10 family cytokines in serum and synovial fluid of patients with inflammatory arthritis reveals different contribution to systemic and joint inflammation

scientific article published on 01 February 2015

Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis

scientific article published on 01 January 2007

Elevated Serum Level of HMGB1 in Patients with the Antiphospholipid Syndrome.

scientific article published on 19 December 2017

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension.

scientific article published on 31 March 2015

Erratum to: Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases.

scientific article published on 16 December 2016

Evaluation of the patient acceptable symptom state (PASS) in Italian patients affected by systemic lupus erythematosus: association with disease activity indices

scientific article

Flare, persistently active disease, and serologically active clinically quiescent disease in systemic lupus erythematosus: a 2-year follow-up study.

scientific article

Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells

scientific article

Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype

scientific article

IL-18 Serum Level in Adult Onset Still's Disease: A Marker of Disease Activity

scientific article published in 2012

Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease

scientific article published on 12 April 2006

Identification of IP-10 and IL-5 as proteins differentially expressed in human complicated and uncomplicated carotid atherosclerotic plaques

scientific article published on 01 July 2010

Increased circulating osteopontin levels in adult patients with type 1 diabetes mellitus and association with dysmetabolic profile

scientific article published on 17 November 2015

Interleukin 18: a biomarker for differential diagnosis between adult-onset Still's disease and sepsis

scientific article published on May 2014

Interleukin-2 profiles shortly after tacrolimus conversion from a twice-daily to once-daily regimen

scientific article published on 01 May 2011

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

scientific article published on 3 June 2015

Joint involvement in systemic lupus erythematosus: From pathogenesis to clinical assessment.

scientific article

Kidney Expression of Toll Like Receptors in Lupus Nephritis: Quantification and Clinicopathological Correlations.

scientific article published on 21 August 2016

Long-term interleukin-2 assessment after conversion from a twice-daily to once-daily tacrolimus regimen in stable kidney recipients

scientific article published on 01 September 2012

Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus

scientific article

Lymph node IL-18 expression in adult-onset Still's disease

scientific article published in March 2009

Markedly increased IL-18 liver expression in adult-onset Still's disease-related hepatitis

scientific article published on 13 December 2010

Mycophenolate mofetil in systemic lupus erythematosus: results from a retrospective study in a large monocentric cohort and review of the literature

scientific article

Nedd5, a novel autoantigen in systemic sclerosis: is it a marker of more severe disease?

scientific article published on 01 January 2010

Neurocognitive dysfunction in systemic lupus erythematosus: association with antiphospholipid antibodies, disease activity and chronic damage

scientific article

New autoantigens in the antiphospholipid syndrome ⬇️

scientific article published on April 27, 2011

Nucleosome accumulation and reduction of C-reactive protein are associated with the generation of anti-nuclear antibodies in patients with rheumatoid arthritis treated with adalimumab, but not with etanercept

scientific article published on 01 September 2009

Pathophysiology of fibromyalgia: a comparison with the tension-type headache, a localized pain syndrome

scientific article published on 01 April 2010

Post-translational modifications in rheumatoid arthritis and atherosclerosis: Focus on citrullination and carbamylation

scientific article

Prediction of chronic damage in systemic lupus erythematosus by using machine-learning models

scientific article

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases

scientific article

Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs

scientific article published on 29 January 2019

Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes

scientific article

Safety profile and causes of withdrawal due to adverse events in systemic lupus erythematosus patients treated long-term with cyclosporine A

scientific article published on 01 January 2000

Screening of a HUAEC cDNA library identifies actin as a candidate autoantigen associated with carotid atherosclerosis

scientific article

Screening of endothelial expression libraries for the identification of novel autoantigens involved in distinct autoimmune diseases characterized by endothelial dysfunction

scientific article

Seronegative autoimmune diseases

scientific article published on 01 September 2009

Serum Anti-β2-glycoprotein I Antibodies from Patients with Antiphospholipid Antibody Syndrome Bind Central Nervous System Cells ⬇️

scientific article published on October 1, 1998

Serum Sclerostin as a Possible Biomarker in Ankylosing Spondylitis: A Case-Control Study.

scientific article

Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease.

scientific article published on September 2013

Subclinical atherosclerosis in systemic lupus erythematosus and antiphospholipid syndrome: focus on β2GPI-specific T cell response

scientific article

Subclinical synovitis in primary Sjögren's syndrome: an ultrasonographic study.

scientific article published on 17 March 2010

Systemic Lupus Erythematosus with and without Anti-dsDNA Antibodies: Analysis from a Large Monocentric Cohort.

scientific article published on 6 May 2015

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

scientific article

TLC immunostaining for detection of "antiphospholipid" antibodies

scientific article published on 01 January 2014

The Role of Posttranslational Protein Modifications in Rheumatological Diseases: Focus on Rheumatoid Arthritis

scientific article

The autoimmune side of rheumatic fever

scientific article published on October 2014

The chronic damage in systemic lupus erythematosus is driven by flares, glucocorticoids and antiphospholipid antibodies: results from a monocentric cohort.

scientific article published on 27 January 2016

The hyperferritinemic syndromes and CD163: a marker of macrophage activation

scientific article published on 01 October 2014

The mosaic of "seronegative" antiphospholipid syndrome

scientific article published on 17 March 2014

The role of anti-cyclic cytrullinate antibodies testing in rheumatoid arthritis.

scientific article published on February 2008

The role of dietary sodium intake on the modulation of T helper 17 cells and regulatory T cells in patients with rheumatoid arthritis and systemic lupus erythematosus.

scientific article published on 6 September 2017

The role of disease activity score 28 in the evaluation of articular involvement in systemic lupus erythematosus

scientific article published on 03 November 2014

Thin-layer chromatography immunostaining in detecting anti-phospholipid antibodies in seronegative anti-phospholipid syndrome ⬇️

scientific article published on March 1, 2012

Toll-like receptors and lupus nephritis.

scientific article published on June 2011

Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis

scientific article

Ultrasonographic Evaluation of Resistive Index and Renal Artery Stenosis in Patients with Anti-Phospholipid Syndrome: Two Distinct Mechanisms?

scientific article published on 21 March 2015

Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide

scientific article published on 28 March 2011

Validation of a disease-specific health-related quality of life measure in adult Italian patients with systemic lupus erythematosus: LupusQoL-IT.

scientific article published on 25 February 2014

Y chromosome microchimerism in Sjögren's syndrome.

scientific article published on November 2001

List of works by Cristiano Alessandri

"New" antigenic targets and methodological approaches for refining laboratory diagnosis of antiphospholipid syndrome

A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene

A polymorphism upstream MIR1279 gene is associated with pericarditis development in Systemic Lupus Erythematosus and contributes to definition of a genetic risk profile for this complication

Acute longitudinal myelitis following Cryptococcus laurentii pneumonia in a patient with systemic lupus erythematosus.

Anti-GAPDH Autoantibodies as a Pathogenic Determinant and Potential Biomarker of Neuropsychiatric Diseases

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus.

Anti-carbamylated protein antibodies in systemic lupus erythematosus patients with articular involvement

Anti-carbonic anhydrase II antibodies in systemic sclerosis: association with lung involvement

Anti-cyclic citrullinated peptide antibody determination in the synovial fluid of patients with rheumatoid arthritis: comment on the article by Caspi et al

Anti-endothelial antibodies and neuropsychiatric systemic lupus erythematosus

Anti-lysobisphosphatidic acid antibodies in patients with antiphospholipid syndrome and systemic lupus erythematosus

Antibodies to age-β2 glycoprotein I in patients with anti-phospholipid antibody syndrome.

Anti–β2-glycoprotein I antibodies induce monocyte release of tumor necrosis factor α and tissue factor by signal transduction pathways involving lipid rafts

Assessment of disease activity in Systemic Lupus Erythematosus: Lights and shadows

Association between Staphylococcus aureus nasal carriage and disease phenotype in patients affected by systemic lupus erythematosus

Association between antibodies to carbamylated proteins and subclinical atherosclerosis in rheumatoid arthritis patients.

Autoantibodies specific to D4GDI modulate Rho GTPase mediated cytoskeleton remodeling and induce autophagy in T lymphocytes

Autoantibodies specific to a peptide of β2-glycoprotein I cross-react with TLR4, inducing a proinflammatory phenotype in endothelial cells and monocytes

Autoantibodies to estrogen receptor α interfere with T lymphocyte homeostasis and are associated with disease activity in systemic lupus erythematosus

Autoantibodies to the C-terminal subunit of RLIP76 induce oxidative stress and endothelial cell apoptosis in immune-mediated vascular diseases and atherosclerosis

Autoantibody production in anti-TNF-alpha-treated patients

Autophagy generates citrullinated peptides in human synoviocytes: a possible trigger for anti-citrullinated peptide antibodies.

Autophagy occurs in lymphocytes infiltrating Sjögren's syndrome minor salivary glands and correlates with histological severity of salivary gland lesions

Avidity of anti-β2-glycoprotein I antibodies in patients with antiphospholipid syndrome

Beta2-glycoprotein I is a target of T cell reactivity in patients with advanced carotid atherosclerotic plaques

Biological therapies in rheumatic diseases

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren's syndrome patients and correlates with focus score and disease activity

Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis.

Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes

Clinical relevance of silent red blood cell autoantibodies

Determination of antibodies to extractable nuclear antigens by commercial kits: a multicenter study.

Distribution of interleukin-10 family cytokines in serum and synovial fluid of patients with inflammatory arthritis reveals different contribution to systemic and joint inflammation

Effect of infliximab on the glycosylation of IgG of patients with rheumatoid arthritis

Elevated Serum Level of HMGB1 in Patients with the Antiphospholipid Syndrome.

Elevated serum levels of macrophage migration inhibitory factor and stem cell growth factor β in patients with idiopathic and systemic sclerosis associated pulmonary arterial hypertension.

Erratum to: Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases.

Evaluation of the patient acceptable symptom state (PASS) in Italian patients affected by systemic lupus erythematosus: association with disease activity indices

Flare, persistently active disease, and serologically active clinically quiescent disease in systemic lupus erythematosus: a 2-year follow-up study.

Gender disparity in susceptibility to oxidative stress and apoptosis induced by autoantibodies specific to RLIP76 in vascular cells

Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype

IL-18 Serum Level in Adult Onset Still's Disease: A Marker of Disease Activity

Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease

Identification of IP-10 and IL-5 as proteins differentially expressed in human complicated and uncomplicated carotid atherosclerotic plaques

Increased circulating osteopontin levels in adult patients with type 1 diabetes mellitus and association with dysmetabolic profile

Interleukin 18: a biomarker for differential diagnosis between adult-onset Still's disease and sepsis

Interleukin-2 profiles shortly after tacrolimus conversion from a twice-daily to once-daily regimen

Interleukin-36α axis is modulated in patients with primary Sjögren's syndrome.

Joint involvement in systemic lupus erythematosus: From pathogenesis to clinical assessment.

Kidney Expression of Toll Like Receptors in Lupus Nephritis: Quantification and Clinicopathological Correlations.

Long-term interleukin-2 assessment after conversion from a twice-daily to once-daily tacrolimus regimen in stable kidney recipients

Low expression of estrogen receptor β in T lymphocytes and high serum levels of anti-estrogen receptor α antibodies impact disease activity in female patients with systemic lupus erythematosus

Lymph node IL-18 expression in adult-onset Still's disease

Markedly increased IL-18 liver expression in adult-onset Still's disease-related hepatitis

Mycophenolate mofetil in systemic lupus erythematosus: results from a retrospective study in a large monocentric cohort and review of the literature

Nedd5, a novel autoantigen in systemic sclerosis: is it a marker of more severe disease?

Neurocognitive dysfunction in systemic lupus erythematosus: association with antiphospholipid antibodies, disease activity and chronic damage

New autoantigens in the antiphospholipid syndrome ⬇️

Nucleosome accumulation and reduction of C-reactive protein are associated with the generation of anti-nuclear antibodies in patients with rheumatoid arthritis treated with adalimumab, but not with etanercept

Pathophysiology of fibromyalgia: a comparison with the tension-type headache, a localized pain syndrome

Post-translational modifications in rheumatoid arthritis and atherosclerosis: Focus on citrullination and carbamylation

Prediction of chronic damage in systemic lupus erythematosus by using machine-learning models

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases

Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs

Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes

Safety profile and causes of withdrawal due to adverse events in systemic lupus erythematosus patients treated long-term with cyclosporine A

Screening of a HUAEC cDNA library identifies actin as a candidate autoantigen associated with carotid atherosclerosis

Screening of endothelial expression libraries for the identification of novel autoantigens involved in distinct autoimmune diseases characterized by endothelial dysfunction

Seronegative autoimmune diseases

Serum Anti-β2-glycoprotein I Antibodies from Patients with Antiphospholipid Antibody Syndrome Bind Central Nervous System Cells ⬇️

Serum Sclerostin as a Possible Biomarker in Ankylosing Spondylitis: A Case-Control Study.

Streptococcal-vimentin cross-reactive antibodies induce microvascular cardiac endothelial proinflammatory phenotype in rheumatic heart disease.

Subclinical atherosclerosis in systemic lupus erythematosus and antiphospholipid syndrome: focus on β2GPI-specific T cell response

Subclinical synovitis in primary Sjögren's syndrome: an ultrasonographic study.

Systemic Lupus Erythematosus with and without Anti-dsDNA Antibodies: Analysis from a Large Monocentric Cohort.

T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

TLC immunostaining for detection of "antiphospholipid" antibodies

The Role of Posttranslational Protein Modifications in Rheumatological Diseases: Focus on Rheumatoid Arthritis

The autoimmune side of rheumatic fever

The chronic damage in systemic lupus erythematosus is driven by flares, glucocorticoids and antiphospholipid antibodies: results from a monocentric cohort.