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List of works by Olaf Merkel

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.

scientific article

Actinomycin D induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia

article by Olaf Merkel et al published 1 June 2012 in Leukemia

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

scientific article published on 12 January 2016

Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin.

scientific article published on 12 May 2014

Anaplastic large cell lymphoma: the current state of play from a European prospective as presented at the second annual meeting of the European Research Initiative on ALCL, 27–28 June 2011

scientific article published on December 1, 2011

Antimyeloma activity of the sesquiterpene lactone cnicin: impact on Pim-2 kinase as a novel therapeutic target.

scientific article

Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13.

scientific article

Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC-wide approach

article published in 2014

Breaking a paradigm: IL-6/STAT3 signaling suppresses metastatic prostate cancer upon ARF expression.

scientific article published on March 2016

Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae.

scientific article

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia

scientific article published on 20 February 2018

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma

scientific article published on 21 August 2018

Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published in Nature Communications

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma

scientific article

First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia.

scientific article published on 27 September 2017

Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression

scientific article published on 30 October 2018

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma

scientific article

Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study

scientific article published on 15 November 2017

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

scientific article published in October 2016

Interleukin-6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus.

scientific article published on 6 January 2016

JAK-STAT signaling in cancer: From cytokines to non-coding genome.

scientific article published on 24 June 2016

JunB and PTEN in prostate cancer: 'loss is nothing else than change'.

scientific article published on April 2015

MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis

scientific article

Mitochondrial phosphate-carrier deficiency: a novel disorder of oxidative phosphorylation

scientific article

Novel therapeutic options in anaplastic large cell lymphoma: molecular targets and immunological tools

scientific article published on 28 June 2011

Novel treatment avenues for peripheral T-cell lymphomas

scientific article published on 24 September 2012

Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation

scientific article

Overview of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic leukemia

scientific article published on 24 June 2013

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas

scientific article

Regulation of activity in vitro and in vivo of three phospholipases B from Saccharomyces cerevisiae.

scientific article published on April 2005

STAT3 regulated ARF expression suppresses prostate cancer metastasis

scientific article published on 22 July 2015

Stem cell hunt in NHL.

scientific article published on 3 September 2015

Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing

scientific article

THE EFFECTS OF MIGRATORY FLIGHT ON HEMATOLOGIC PARAMETERS IN NORTHERN BALD IBISES ( GERONTICUS EREMITA).

scientific article published in December 2017

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

scientific article published on 28 March 2018

The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas

scientific article published on 28 March 2018

The role of essential pyrimidines in the hairpin ribozyme-catalysed reaction

scientific article published on 01 May 1999

When the guardian sleeps: Reactivation of the p53 pathway in cancer

scientific article published on 17 February 2017

miR-150 downregulation contributes to the high-grade transformation of follicular lymphoma by upregulating FOXP1 levels

scientific article published on 13 September 2018

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia

scientific article published on 20 January 2010

p53-dependent non-coding RNA networks in chronic lymphocytic leukemia.

scientific article published on 14 May 2015