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List of works by Giovanna Mantovani

2q37 Deletions in Patients With an Albright Hereditary Osteodystrophy Phenotype and PTH Resistance

scientific article published on 29 August 2019

A Rare SPRY4 Gene Mutation Is Associated With Anosmia and Adult-Onset Isolated Hypogonadotropic Hypogonadism

scientific article published on 12 November 2019

A severe inactivating PTH/PTHrP signaling disorder type 2 in a patient carrying a novel large deletion of the GNAS gene: a case report and review of the literature

scientific article published on 14 January 2020

Absence of thyroid transcription factor-1 expression in human parathyroid and pituitary glands

scientific article published on 01 August 2001

Activation of the dopamine receptor type-2 (DRD2) promoter by 9-cis retinoic acid in a cellular model of Cushing's disease mediates the inhibition of cell proliferation and ACTH secretion without a complete corticotroph-to-melanotroph transdifferent

scientific article

Activity and function of the nuclear factor kappaB pathway in human parathyroid tumors.

scientific article published on December 2005

An alternate translation initiation site circumvents an amino-terminal DAX1 nonsense mutation leading to a mild form of X-linked adrenal hypoplasia congenita

scientific article

Analysis of genetic variants of phosphodiesterase 11A in acromegalic patients.

scientific article

Autosomal dominant pseudohypoparathyroidism type Ib: a novel inherited deletion ablating STX16 causes loss of imprinting at the A/B DMR.

scientific article published on 17 January 2014

Biallelic expression of the Gsalpha gene in human bone and adipose tissue.

scientific article published in December 2004

Brachydactyly and atrial septal defect: when the digits point to the heart

scientific article published on 12 October 2014

Cabergoline Withdrawal Before and After Menopause: Outcomes in Microprolactinomas

scientific article published on 18 April 2019

Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and nonhematopoietic cells

scientific article published on 14 August 2008

Central hypogonadism in Klinefelter syndrome: report of two cases and review of the literature

scientific article published on 14 June 2020

Characterization of intracellular signaling mediated by human somatostatin receptor 5: role of the DRY motif and the third intracellular loop

scientific article published on 02 April 2009

Clinical review: Pseudohypoparathyroidism: diagnosis and treatment.

scientific article published on 03 August 2011

Clinical utility gene card for: pseudohypoparathyroidism

scientific article published on 12 September 2012

Clinically non-functioning pituitary incidentalomas: characteristics and natural history

scientific article published on 13 September 2019

Cushing's disease: a prospective case-control study of health-related quality of life and cognitive status before and after surgery

scientific article published on 15 November 2019

Cyclic adenosine 3'-5'-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac).

scientific article published on 25 December 2013

Cytoskeleton protein Filamin A is required for efficient Somatostatin receptor type 2 internalization and recycling through Rab5 and Rab4 sorting endosomes in tumor somatotroph cells

scientific article published on 01 October 2019

DAX1 and X-linked adrenal hypoplasia congenita: clinical and molecular analysis in five patients

scientific article published on 01 May 2006

Deciphering the specific role of G(αi/o) isoforms: functional selective oxytocin ligands and somatostatin SST5 receptor mutants

scientific article published on February 2013

Determinants of outcome of transsphenoidal surgery for Cushing disease in a single-centre series

scientific article published on 26 November 2019

Diagnosis and management of pseudohypoparathyroidism and related disorders: first international Consensus Statement

article by Giovanna Mantovani et al published August 2018 in Nature Reviews Endocrinology

Diagnostic features and outcome of surgical therapy of acromegalic patients: experience of the last three decades

scientific article published on January 2014

Different expression of protein kinase A (PKA) regulatory subunits in normal and neoplastic thyroid tissues

scientific article

Dopamine and Somatostatin Analogues Resistance of Pituitary Tumors: Focus on Cytoskeleton Involvement

scientific article

Double pituitary and conserved function in an adult patient with neurofibromatosis type 1.

scientific article published in July 2011

Effect of 9-cis retinoic acid on dopamine D2 receptor expression in pituitary adenoma cells

scientific article

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

scientific article

European guidance for the molecular diagnosis of pseudohypoparathyroidism not caused by point genetic variants at GNAS: an EQA study

article published in 2015

Evolution of an aggressive prolactinoma into a growth hormone secreting pituitary tumor coincident with GNAS gene mutation

scientific article published on 4 November 2009

Expression of protein kinase A regulatory subunits in benign and malignant human thyroid tissues: A systematic review

scientific article published on 16 June 2016

Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas

scientific article published on 9 August 2005

Expression of the two alternatively spliced PRKAR1A RNAs in human endocrine glands

scientific article published on 01 June 2005

FGF23 and Fetuin-A Interaction and Mesenchymal Osteogenic Transformation

scientific article published on 20 February 2019

Falling too Fahr ⬇️

scientific article published on January 21, 2012

Fibrocartilaginous mesenchymoma of bone: a single-institution experience with molecular investigations and a review of the literature

scientific article

Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells.

scientific article published on 14 May 2014

Filamin A in somatostatin and dopamine receptor regulation in pituitary and the role of cAMP/PKA dependent phosphorylation.

scientific article

Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs.

scientific article published on 18 January 2012

Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours.

scientific article published on 5 January 2016

From pseudohypoparathyroidism to inactivating PTH/PTHrP signalling disorder (iPPSD), a novel classification proposed by the EuroPHP network

scientific article

GH response to oral glucose tolerance test: a comparison between patients with acromegaly and other pituitary disorders.

scientific article published on 20 October 2010

GNAS epigenetic defects and pseudohypoparathyroidism: time for a new classification?

scientific article published on 06 June 2012

GNAS imprinting and pituitary tumors.

scientific article published on 14 April 2010

Genetic Analysis and Evaluation of Resistance to Thyrotropin and Growth Hormone-Releasing Hormone in Pseudohypoparathyroidism Type Ib

article by Giovanna Mantovani et al published September 2007 in The Journal of Clinical Endocrinology and Metabolism

Genetic abnormalities of somatostatin receptors in pituitary tumors.

scientific article published on 31 August 2007

Genetic and epigenetic defects at the GNAS locus lead to distinct patterns of skeletal growth but similar early-onset obesity.

scientific article published on 25 April 2018

Genetics of Pituitary Tumors: Focus on G-Protein Mutations ⬇️

scientific article published on October 1, 2003

Genome-wide DNA methylation analysis of pseudohypoparathyroidism patients with GNAS imprinting defects.

scientific article published on 26 January 2016

Growth hormone therapy at the time of Covid-19 pandemic: adherence and drug supply issues

scientific article published on 01 July 2020

Growth hormone-releasing hormone resistance in pseudohypoparathyroidism type ia: new evidence for imprinting of the Gs alpha gene.

scientific article published in September 2003

Growth hormone-releasing hormone-producing pancreatic neuroendocrine tumor in a multiple endocrine neoplasia type 1 family with an uncommon phenotype

HESX1 expression in human normal pituitaries and pituitary adenomas.

scientific article published on 18 January 2006

High expression of PKA regulatory subunit 1A protein is related to proliferation of human melanoma cells

scientific article published in October 2007

Hormonal signaling and pituitary adenomas.

scientific article published on 28 February 2007

Hyperandrogenism by Liquid Chromatography Tandem Mass Spectrometry in PCOS: Focus on Testosterone and Androstenedione

scientific article published on 31 December 2020

Hypercalcitoninaemia in pseudohypo-parathyroidism type 1A and type 1B

Hypercoagulability in patients with Cushing disease detected by thrombin generation assay is associated with increased levels of neutrophil extracellular trap-related factors

scientific article published on 22 July 2016

Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita

scientific article published in January 2002

Hyponatremia: a challenge for internists

scientific article published on 10 September 2015

HypoparaNet: A Database of Chronic Hypoparathyroidism Based on Expert Medical-Surgical Centers in Italy

scientific article published on 6 March 2018

Hypothalamic-Pituitary Axis in Non-Functioning Pituitary Adenomas: Focus on the Prevalence of Isolated Central Hypoadrenalism

scientific article published on 29 April 2015

Hypothyroidism associated with parathyroid disorders.

scientific article

Identification of human somatostatin receptor 2 domains involved in internalization and signaling in QGP-1 pancreatic neuroendocrine tumor cell line

scientific article published on 12 July 2016

Improved Molecular Diagnosis of McCune-Albright Syndrome and Bone Fibrous Dysplasia by Digital PCR

scientific article published on 18 September 2019

Inactivating PTH/PTHrP Signaling Disorders

scientific article published on 19 November 2018

Inactivating PTH/PTHrP signaling disorders (iPPSDs): evaluation of the new classification in a multicenter large series of 544 molecularly characterized patients

scientific article published on 01 December 2020

Induction of specific phosphodiesterase isoforms by constitutive activation of the cAMP pathway in autonomous thyroid adenomas

scientific article published on 01 August 2000

Is Complex Sphenoidal Sinus Anatomy a Contraindication to a Transsphenoidal Approach for Resection of Sellar Lesions? Case Series and Review of the Literature

scientific article published on 5 January 2017

Is the 250 μg ACTH test a useful tool for the diagnosis of central hypoadrenalism in adult patients with pituitary disorders?

scientific article

Isolated follicle-stimulating hormone (FSH) deficiency in a young man with normal virilization who did not have mutations in the FSHbeta gene

scientific article

Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas.

scientific article published on 23 December 2015

Long-Standing Isolated Autoimmune Hypothalamitis Diagnosed with Endoscopic Transventricular Biopsy.

scientific article published on 15 June 2017

MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2.

scientific article published on 30 April 2019

Mechanisms of disease: Mutations of G proteins and G-protein-coupled receptors in endocrine diseases.

scientific article published on December 2006

Modulation of cyclin D1 expression in human tumoral parathyroid cells: Effects of growth factors and calcium sensing receptor activation

scientific article published on 04 May 2007

Mosaicism for GNAS methylation defects associated with pseudohypoparathyroidism type 1B arose in early post-zygotic phases

scientific article published on 6 February 2018

Multiple hormone resistance and alterations of G-protein-coupled receptors signaling

scientific article published on 31 January 2018

Mutational analysis of PRKAR1A and Gs(alpha) in sporadic adrenocortical tumors.

scientific article

Mutations in the Gs alpha gene causing hormone resistance

scientific article

Natural history of Rathke's cleft cysts: A retrospective analysis of a two centres experience

scientific article published on 12 June 2018

Novel microdeletions affecting the GNAS locus in pseudohypoparathyroidism: characterization of the underlying mechanisms

scientific article published on 16 January 2015

Octreotide promotes apoptosis in human somatotroph tumor cells by activating somatostatin receptor type 2.

scientific article

PKA regulatory subunit R2B is required for murine and human adipocyte differentiation

scientific article

PRKAR1A and PDE4D mutations cause acrodysostosis but two distinct syndromes with or without GPCR-signaling hormone resistance

scientific article published on 5 October 2012

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

scientific article

Parathyroid hormone resistance syndromes - Inactivating PTH/PTHrP signaling disorders (iPPSDs)

scientific article published on 28 September 2018

Parental origin of Gsalpha mutations in the McCune-Albright syndrome and in isolated endocrine tumors

scientific article published in June 2004

Pathogenesis of prolactinomas.

scientific article

Patients with macroprolactinaemia: clinical and radiological features.

scientific article published on July 2007

Potent constitutive cyclic AMP-generating activity of XLαs implicates this imprinted GNAS product in the pathogenesis of McCune-Albright syndrome and fibrous dysplasia of bone.

scientific article

Procoagulant imbalance in Klinefelter syndrome assessed by thrombin generation assay and whole blood thromboelastometry

scientific article published on 31 December 2020

Prognostic factors in ectopic Cushing's syndrome due to neuroendocrine tumors: a multicenter study.

scientific article published in April 2017

Proliferation of transformed somatotroph cells related to low or absent expression of protein kinase a regulatory subunit 1A protein.

scientific article published in December 2004

Prompt clinical and biochemical response to denosumab in a young adult patient with craniofacial fibrous dysplasia

scientific article published on September 2016

Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects

scientific article published on 18 December 2008

Pseudohypoparathyroidism and Gsα-cAMP-linked disorders: current view and open issues.

scientific article published on 22 April 2016

Pseudohypoparathyroidism andGNASEpigenetic Defects: Clinical Evaluation of Albright Hereditary Osteodystrophy and Molecular Analysis in 40 Patients

article

Pseudohypoparathyroidism type Ia and pseudo-pseudohypoparathyroidism: the growing spectrum of GNAS inactivating mutations

scientific article published on 18 January 2013

Pseudohypoparathyroidism type Ia: a novel GNAS mutation in a Brazilian boy presenting with an early primary hypothyroidism.

scientific article published in January 2013

Pseudohypoparathyroidism type Ib in 2015.

scientific article published on 21 April 2015

Pseudohypoparathyroidism, acrodysostosis, progressive osseous heteroplasia: different names for the same spectrum of diseases?

scientific article published on 11 November 2020

Quantitative analysis of methylation defects and correlation with clinical characteristics in patients with pseudohypoparathyroidism type I and GNAS epigenetic alterations.

scientific article published in January 2013

Rathke's cleft cyst associated with pituitary granulomatosis with polyangiitis: An unusual combination of hypothalamus-pituitary region pathologies.

scientific article published on 31 October 2017

Recombinant human GH replacement therapy in children with pseudohypoparathyroidism type Ia: first study on the effect on growth

scientific article published on 18 August 2010

Recommendations for Diagnosis and Treatment of Pseudohypoparathyroidism and Related Disorders: An Updated Practical Tool for Physicians and Patients

scientific article published on 05 August 2020

Recovery of Adrenal Function after Pituitary Surgery in Patients with Cushing Disease: Persistent Remission or Recurrence?

scientific article published on 13 January 2019

Reevaluation of Acromegalic Patients in Long-Term Remission according to Newly Proposed Consensus Criteria for Control of Disease

scientific article

Resistance to growth hormone releasing hormone and gonadotropins in Albright's hereditary osteodystrophy

scientific article published on May 2006

Role of IGF1-(CA)19 promoter microsatellite in the clinical presentation of acromegaly

scientific article

Role of UGT1A1 and ADH gene polymorphisms in pegvisomant-induced liver toxicity in acromegalic patients

scientific article published on 21 December 2013

SARS-CoV-2-related atypical thyroiditis

scientific article published on 30 July 2020

SAT-566 Cofilin Is a Mediator of RET-Promoted Medullary Thyroid Carcinoma Cell Migration, Invasion and Proliferation

Screening for ACTH-dependent hypercortisolism in patients affected with pituitary incidentaloma.

scientific article published on April 2015

Screening of PRKAR1A and PDE4D in a Large Italian Series of Patients Clinically Diagnosed With Albright Hereditary Osteodystrophy and/or Pseudohypoparathyroidism

scientific article

Severe water intoxication secondary to the concomitant intake of non-steroidal anti-inflammatory drugs and desmopressin: a case report and review of the literature ⬇️

scientific article published on January 1, 2013

Single-Molecule Microscopy Reveals Dynamic FLNA Interactions Governing SSTR2 Clustering and Internalization

scientific article published on 01 August 2018

Somatic mutational analysis of DAX1 in testes from men with idiopathic azoospermia

scientific article published in November 2005

Somatostatin analogs regulate tumor corticotrophs growth by reducing ERK1/2 activity

scientific article published on 03 January 2019

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells

scientific article

Specific roles of Giprotein family members revealed by dissecting SST5 coupling in human pituitary cells

scientific article published in 2014

Stem Cells in Pituitary Tumors: Experimental Evidence Supporting Their Existence and Their Role in Tumor Clinical Behavior

scientific article published on 25 October 2019

TNM 8th edition in thyroid cancer staging: is there an improvement in predicting recurrence?

scientific article published on 01 March 2020

Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas.

scientific article

The Importance of Networking in Pseudohypoparathyroidism: EuroPHP Network and Patient Support Associations

scientific article published on 01 November 2017

The Prevalence of GNAS Deficiency-Related Diseases in a Large Cohort of Patients Characterized by the EuroPHP Network.

scientific article published on 18 July 2016

The dopamine-somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways.

scientific article published on 19 July 2009

The gsalpha gene: predominant maternal origin of transcription in human thyroid gland and gonads

scientific article published in October 2002

The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis

scientific article published on 01 July 2019

The microRNA cluster C19MC is deregulated in parathyroid tumours.

scientific article published on 26 July 2012

The suprasellar volume of nonfunctioning pituitary adenomas: a useful tool for predicting visual field deficits

scientific article published on 19 June 2020

The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation

scientific article published on 20 December 2007

Thyrotropin-secreting pituitary adenomas: outcome of pituitary surgery and irradiation

scientific article published on 19 February 2014

Transphenoidal surgery in acromegalic patients: anatomical considerations and potential pitfalls.

scientific article published on 25 November 2012

Treatment of Acromegalic Osteopathy in Real-Life Clinical Practice: The BAAC (Bone Active drugs in ACromegaly) Study

scientific article published on 08 June 2020

Tumor-Educated Platelets and Angiogenesis in Glioblastoma: Another Brick in the Wall for Novel Prognostic and Targetable Biomarkers, Changing the Vision from a Localized Tumor to a Systemic Pathology

scientific article published on 25 January 2020

Unrecognized Pseudohypoparathyroidism Type 1A as a Cause of Hypocalcemia and Seizures in a 64-Year-Old Woman

scientific article published on 09 January 2019

VERTEBRAL FRACTURES ASSOCIATED WITH SPINAL SAGITTAL IMBALANCE AND QUALITY OF LIFE IN ACROMEGALY: A RADIOGRAPHIC STUDY WITH EOS 2D/3D TECHNOLOGY

scientific article published on 25 September 2020

X-linked acrogigantism syndrome: clinical profile and therapeutic responses

scientific article

cAMP in the pituitary: an old messenger for multiple signals.

scientific article

cAMP pathway and pituitary tumorigenesis.

scientific article published on 22 April 2012

β-arrestin 2 is required for dopamine receptor type 2 inhibitory effects on AKT phosphorylation and cell proliferation in pituitary tumors

scientific article published on 08 June 2020

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