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List of works by Vittorio Rosti

A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.

scientific article published in January 2015

A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

scientific article published on 10 October 2019

A prospective evaluation of pegylated interferon alfa-2a therapy in patients with polycythemia vera and essential thrombocythemia with a prior splanchnic vein thrombosis

scientific article published on 30 July 2019

A subpopulation of circulating endothelial cells express CD109 and is enriched in the blood of cancer patients.

scientific article

Acquired cyclic thrombocytopenia-thrombocytosis with periodic defect of platelet function.

scientific article

Altered fibronectin expression and deposition by myeloproliferative neoplasm-derived mesenchymal stromal cells

scientific article published on 5 May 2015

Anaemia characterises patients with myelofibrosis harbouring Mpl mutation.

scientific article published in May 2007

Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.

scientific article published on 10 January 2017

Apoptosis: biological and clinical aspects.

scientific article published in January 1994

Arachidonic acid-evoked Ca2+ signals promote nitric oxide release and proliferation in human endothelial colony forming cells

scientific article published on 12 September 2016

Autografting with Ph-negative progenitors in patients at diagnosis of chronic myeloid leukemia induces a prolonged prevalence of Ph-negative hemopoiesis

scientific article published on 01 February 2000

Biological and clinical relevance of matrix metalloproteinases 2 and 9 in acute myeloid leukaemias and myelodysplastic syndromes.

scientific article

Biological, functional and genetic characterization of bone marrow-derived mesenchymal stromal cells from pediatric patients affected by acute lymphoblastic leukemia

scientific article published on 7 November 2013

Blast phase myeloproliferative neoplasm: Mayo-AGIMM study of 410 patients from two separate cohorts.

scientific article published on 2 February 2018

Breast and renal cancer-Derived endothelial colony forming cells share a common gene signature.

scientific article

C-fms expression in B-cells and response to M-CSF

scientific article published on 01 August 1993

CD14(bright)CD16(low) intermediate monocytes expressing Tie2 are increased in the peripheral blood of patients with primary myelofibrosis

scientific article

Ca2+ signalling in endothelial progenitor cells: a novel means to improve cell-based therapy and impair tumour vascularisation

scientific article published on 01 January 2014

Canonical transient receptor potential 3 channel triggers vascular endothelial growth factor-induced intracellular Ca2+ oscillations in endothelial progenitor cells isolated from umbilical cord blood

scientific article published on 25 June 2013

Case 37-1994: juvenile chronic myelogenous leukemia

scientific article published on 01 February 1995

Cell cycle distribution of cord blood-derived haematopoietic progenitor cells and their recruitment into the S-phase of the cell cycle

scientific article published on 01 March 2000

Cell fusion in tumor progression: the isolation of cell fusion products by physical methods

scientific article

Cell kinetics of CD34-positive hematopoietic cells following chemotherapy plus colony-stimulating factors in advanced breast cancer

scientific article published on 01 November 1995

Chronic myelogenous leukemia following radiotherapy and chemotherapy for non-Hodgkin lymphoma.

scientific article published on September 1990

Circulating CD34+, CD133+, and Vascular Endothelial Growth Factor Receptor 2–Positive Endothelial Progenitor Cells in Myelofibrosis With Myeloid Metaplasia

Circulating endothelial progenitor cells in preterm infants with bronchopulmonary dysplasia

scientific article published on 2 July 2009

Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis

scientific article

Comprehensive characterization of mesenchymal stromal cells from patients with Fanconi anaemia

scientific article

Conditioned medium from human amniotic mesenchymal stromal cells limits infarct size and enhances angiogenesis

scientific article published on 30 March 2015

Congenital amegakaryocytic thrombocytopenia: clinical and biological consequences of five novel mutations.

scientific article

Conjugated polymers optically regulate the fate of endothelial colony-forming cells

scientific article published on 27 September 2019

Constitutive STAT5 phosphorylation in CD34+ cells of patients with primary myelofibrosis: Correlation with driver mutation status and disease severity

scientific article published on 01 August 2019

Constitutive Store-Operated Ca(2+) Entry Leads to Enhanced Nitric Oxide Production and Proliferation in Infantile Hemangioma-Derived Endothelial Colony-Forming Cells

scientific article published on 9 December 2015

Cytotoxic activity of an anti-transferrin receptor immunotoxin on normal and leukemic human hematopoietic progenitors.

scientific article published on January 1991

Defective iron supply for erythropoiesis and adequate endogenous erythropoietin production in the anemia associated with systemic-onset juvenile chronic arthritis

scientific article published on 01 June 1996

Diagnostic and clinical relevance of the number of circulating CD34+ cells in myelofibrosis with myeloid metaplasia

Different subsets of circulating angiogenic cells do not predict bronchopulmonary dysplasia or other diseases of prematurity in preterm infants

scientific article published on 01 July 2013

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms.

scientific article published on 9 October 2015

Dysregulation of VEGF-induced proangiogenic Ca2+ oscillations in primary myelofibrosis-derived endothelial colony-forming cells

scientific article published on 19 October 2015

EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis

scientific article published on 07 February 2019

Early haemoglobin-independent increase of plasma erythropoietin levels in patients with acute myocardial infarction

scientific article published on 05 April 2007

Effect of recombinant human erythropoietin on hematopoietic and non-hematopoietic malignant cell growth in vitro

scientific article published on 01 July 1993

Effects of mitochondrial ferritin overexpression in normal and sideroblastic erythroid progenitors.

scientific article published on 10 April 2013

Effects of the R216Q mutation of GATA-1 on erythropoiesis and megakaryocytopoiesis

scientific article

Elevated C-reactive protein is associated with shortened leukemia-free survival in patients with myelofibrosis.

scientific article published on 5 July 2013

Endoplasmic Reticulum Ca(2+) Handling and Apoptotic Resistance in Tumor-Derived Endothelial Colony Forming Cells.

scientific article published on 24 February 2016

Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-specific molecular clonality marker

scientific article published on 23 July 2009

Endothelial progenitor cells support tumour growth and metastatisation: implications for the resistance to anti-angiogenic therapy.

scientific article published on 02 August 2015

Endothelial-to-Mesenchymal Transition in Bone Marrow and Spleen of Primary Myelofibrosis.

scientific article published on August 2017

Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis

scientific article

Erythrophagocytosis increases the expression of erythroid potentiating activity mRNA in human monocyte-macrophages

scientific article published on 01 January 1993

Evaluation of erythroid marrow response to recombinant human erythropoietin in patients with cancer anaemia ⬇️

scientific article published on 01 November 1992

Evaluation of the Effect of Medroxyprogesterone Acetate on Bone Marrow Progenitor Cells ⬇️

scientific article published on October 31, 1991

Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis.

scientific article published on 30 August 2010

Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosis

scientific article

Ex vivo priming for long-term maintenance of antileukemia human cytotoxic T cells suggests a general procedure for adoptive immunotherapy.

scientific article

Expression and function of toll-like receptors in human circulating endothelial colony forming cells.

scientific article

FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells

scientific article published on 11 January 2007

Fine structural detection of calcium ions by photoconversion

scientific article published on 10 August 2016

Functional and genetic aberrations of in vitro-cultured marrow-derived mesenchymal stromal cells of patients with classical Philadelphia-negative myeloproliferative neoplasms

scientific article published on 12 March 2014

Generation of donor-derived Wilms tumor antigen 1-specific cytotoxic T lymphocytes with potent anti-leukemia activity for somatic cell therapy in children given haploidentical stem cell transplantation: a feasibility pre-clinical study

scientific article published on 04 July 2019

Germ-line mutation of the NRAS gene may be responsible for the development of juvenile myelomonocytic leukaemia

scientific article published on 22 September 2009

Glycosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development.

scientific article published in September 2002

High frequency of endothelial colony forming cells marks a non-active myeloproliferative neoplasm with high risk of splanchnic vein thrombosis

scientific article

High-dose erythropoietin in patients with acute myocardial infarction: A pilot, randomised, placebo-controlled study

scientific article published on 10 November 2009

How to utilize Ca²⁺ signals to rejuvenate the repairative phenotype of senescent endothelial progenitor cells in elderly patients affected by cardiovascular diseases: a useful therapeutic support of surgical approach?

scientific article

Hydrogen sulphide triggers VEGF-induced intracellular Ca²⁺ signals in human endothelial cells but not in their immature progenitors.

scientific article published on 27 July 2014

Hypermethylation of CXCR4 promoter in CD34+ cells from patients with primary myelofibrosis.

scientific article

Idarubicin-containing regimen and G-CSF are capable of recruiting CD34+/DR- cells with high proliferative potential which sustain Ph-negative polyclonal hematopoiesis

scientific article published on 01 January 1994

Immunocytochemical detection of ferritin in human bone marrow and peripheral blood cells using monoclonal antibodies specific for the H and L subunit

scientific article published on 01 November 1990

In vitro and in vivo effects of recombinant interferon gamma on the growth of hematopoietic progenitor cells from patients with myelodysplastic syndrome.

scientific article published in September 1989

In vitro growth of bone marrow-derived multipotent and lineage-restricted hematopoietic progenitor cells in myelodysplastic syndromes

scientific article published on 01 March 1989

In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes.

scientific article

Increase of circulating endothelial cells in patients with Hereditary Hemorrhagic Telangiectasia.

scientific article published on 3 December 2014

Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction

scientific article published on 02 September 2004

Increased plasma nicotinamide phosphoribosyltransferase is associated with a hyperproliferative phenotype and restrains disease progression in MPN-associated myelofibrosis.

scientific article

Inhibition of c-ABL expression in hematopoietic progenitor cells using antisense oligodeoxynucleotides

scientific article published on 01 January 2000

Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines.

scientific article published on December 1993

Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.

scientific article

Interferon-α protects Philadelphia-negative progenitors from exhaustion in chronic myeloid leukemia patients with cytogenetic response

scientific article published on 01 January 2001

Intravenous iron therapy for severe anaemia in systemic-onset juvenile chronic arthritis

scientific article published on 01 October 1994

Involvement of MAF/SPP1 axis in the development of bone marrow fibrosis in PMF patients

scientific article

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

scientific article published on 12 February 2013

JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis

scientific article

JAK2 V617F mutational status predicts progression to large splenomegaly and leukemic transformation in primary myelofibrosis.

scientific article published on 21 August 2007

JAK2 exon 14 skipping in patients with primary myelofibrosis: a minor splice variant modulated by the JAK2-V617F allele burden

scientific article published on 24 January 2015

JAK2(V617F) allele burden ⩾50% is associated with response to ruxolitinib in persons with MPN-associated myelofibrosis and splenomegaly requiring therapy.

scientific article published on 29 February 2016

Juvenile chronic myelogenous leukemia: in vitro characterization before and after allogeneic bone marrow transplantation

scientific article published on 01 March 1995

Kinetic and Angiogenic Activity of Circulating Endothelial Colony Forming Cells in Patients with Infantile Haemangioma Receiving Propranolol

scientific article published on 04 January 2019

Liposomes as a Putative Tool to Investigate NAADP Signaling in Vasculogenesis

scientific article

Management of Myeloproliferative Neoplasms: From Academic Guidelines to Clinical Practice ⬇️

scientific article published on March 1, 2012

Manipulating Intracellular Ca2+ Signals to Stimulate Therapeutic Angiogenesis in Cardiovascular Disorders

scientific article published on 01 January 2018

Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.

scientific article published on September 1997

Murine models of paroxysmal nocturnal hemoglobinuria.

scientific article

Myelodysplastic syndromes: mechanisms of transformation and neoplastic progression and their clinical implications ⬇️

scientific article published on June 1, 1991

No association between the XPD Lys751Gln (rs13181) polymorphism and disease phenotype or leukemic transformation in primary myelofibrosis.

scientific article published on 28 May 2013

Normal primitive haemopoietic progenitors are more frequent than their leukaemic counterpart in newly diagnosed patients with chronic myeloid leukaemia but rapidly decline with time

scientific article published on 01 March 1999

Novel strategies for patients with chronic myeloproliferative disorders.

scientific article published on March 2009

Oligodeoxynucleotides antisense to c-abl specifically inhibit entry into S-phase of CD34+ hematopoietic cells and their differentiation to granulocyte-macrophage progenitors

scientific article published on 01 November 1995

Overexpression of the Doppel protein in acute myeloid leukaemias and myelodysplastic syndromes

scientific article published on 01 March 2005

Parental origin of the deletion del(20q) in Shwachman-Diamond patients and loss of the paternally derived allele of the imprinted L3MBTL1 gene.

scientific article published on 24 August 2016

Pathogenesis of chronic myelogenous leukemia.

scientific article published in January 1994

Presentation and outcome of patients with 2016 WHO diagnosis of prefibrotic and overt primary myelofibrosis.

scientific article

Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment.

scientific article

Primary myelofibrosis: Older age and high JAK2V617F allele burden are associated with elevated plasma high-sensitivity C-reactive protein levels and a phenotype of progressive disease.

scientific article published on 7 June 2017

Prognostic impact of bone marrow fibrosis in primary myelofibrosis. A study of the AGIMM group on 490 patients.

scientific article

Rapid and large increase of the frequency of circulating endothelial colony-forming cells (ECFCs) generating late outgrowth endothelial cells in patients with acute myocardial infarction

scientific article published on 13 November 2008

Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib.

scientific article published on 22 October 2013

Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting using the human amniotic fluid stem cell secretome

scientific article published on 04 April 2019

Reduced frequency of circulating CD4+CD25brightCD127lowFOXP3+ regulatory T cells in primary myelofibrosis

scientific article published on 16 August 2016

Regulation of erythropoietin production in a case of congenital erythropoietin-dependent pure erythrocytosis

scientific article published on 01 August 1994

Remote ischemic post-conditioning of the lower limb during primary percutaneous coronary intervention safely reduces enzymatic infarct size in anterior myocardial infarction: a randomized controlled trial

scientific article published in October 2013

Restoration of normal polyclonal haemopoiesis in patients with chronic myeloid leukaemia autografted with Ph-negative peripheral stem cells

scientific article published on 01 August 1994

Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis

scientific article published on 16 November 2018

Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial.

scientific article published on 21 April 2016

Safety and efficacy of ruxolitinib in splanchnic vein thrombosis associated with myeloproliferative neoplasms.

scientific article published on 23 November 2016

Spleen endothelial cells from patients with myelofibrosis harbor the JAK2V617F mutation.

scientific article

Spleen neoangiogenesis in patients with myelofibrosis with myeloid metaplasia

scientific article published in March 2004

Splenectomy produces a rapid but transient decrease of the frequency of circulating CD34+ haematopoietic progenitor cells in primary myelofibrosis

scientific article published on 23 January 2011

Store-dependent Ca(2+) entry in endothelial progenitor cells as a perspective tool to enhance cell-based therapy and adverse tumour vascularization.

scientific article published on January 2012

Store-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma.

scientific article

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

scientific article

Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways.

scientific article published on 9 November 2017

Subcutaneous erythropoietin for treatment of refractory anemia in hematologic disorders. Results of a phase I/II clinical trial ⬇️

scientific article published on 01 January 1992

Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer Therapy.

scientific article

The early- and intermediate-term toxicity to primitive hematopoietic progenitor cells of three chemotherapy regimens for advanced hodgkin lymphoma.

scientific article published in December 2009

The expression of CXCR4 is down-regulated on the CD34+ cells of patients with myelofibrosis with myeloid metaplasia

scientific article

The role of endothelial colony forming cells in kidney cancer's pathogenesis, and in resistance to anti-VEGFR agents and mTOR inhibitors: A speculative review

scientific article published on 18 September 2018

The spleen of patients with myelofibrosis harbors defective mesenchymal stromal cells

scientific article

The syndrome of abnormal chromatin clumping in leucocytes: clinical and biological study of a case.

scientific article

Therapeutic approaches in myelofibrosis.

scientific article published on 04 April 2011

Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis.

scientific article published on 9 January 2016

Tie2 Expressing Monocytes in the Spleen of Patients with Primary Myelofibrosis

scientific article

Treatment with retinoids and haemopoietic growth factors in myelodysplastic syndromes

scientific article published on 01 November 1995

Tumor necrosis factor alpha modulates the messenger RNA expression of hematopoietic growth factor genes in fresh blast cells from patients with acute myeloblastic leukemia

scientific article published on 01 October 1991

Unbalanced X‐chromosome inactivation in haemopoietic cells from normal women ⬇️

scientific article published on September 1, 1998

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

scientific article

VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells

scientific article published on 14 August 2017

Vascular endothelial growth factor overexpression in myelodysplastic syndrome bone marrow cells: biological and clinical implications

scientific article published on 29 November 2016

Vascular endothelial growth factor promoted endothelial progenitor cell mobilization into the peripheral blood of a patient with POEMS syndrome

scientific article published on 01 September 2007

Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration.

scientific article published in November 2011

miR-494-3p overexpression promotes megakaryocytopoiesis in primary myelofibrosis hematopoietic stem/progenitor cells by targeting SOCS6.

scientific article published on March 2017

miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis

scientific article

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