List of works - Nicoletta Plotegher

Alpha-synuclein pore forming activity upon membrane association

article by Laura Tosatto et al published November 2012 in BBA - Biomembranes

Biophysical groundwork as a hinge to unravel the biology of α-synuclein aggregation and toxicity

scientific article published on 21 January 2014

Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses

article

Comprehensive Structural and Thermodynamic Analysis of Prefibrillar WT α-Synuclein and Its G51D, E46K, and A53T Mutants by a Combination of Small-Angle X-ray Scattering and Variational Bayesian Weighting

scientific article published on 17 September 2020

Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease

scientific article published on 12 December 2017

DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.

scientific article published on 13 January 2017

Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues

scientific article published on 22 October 2020

Erratum to: Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells.

scientific article published on April 2016

High-Pressure-Driven Reversible Dissociation of α-Synuclein Fibrils Reveals Structural Hierarchy.

scientific article published in October 2017

Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload

scientific article published on 04 November 2019

Impaired dopamine metabolism in Parkinson's disease pathogenesis

scientific article published on 20 August 2019

LRRK2 deficiency impacts ceramide metabolism in brain.

scientific article published on 15 August 2016

LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate

scientific article published on 13 January 2016

Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells

scientific article published on 9 December 2015

Lysines, Achilles' heel in alpha-synuclein conversion to a deadly neuronal endotoxin

scientific article published on 09 December 2015

Mitochondrial Dysfunction and Neurodegeneration in Lysosomal Storage Disorders.

scientific article published on 19 January 2017

NADH fluorescence lifetime is an endogenous reporter of α-synuclein aggregation in live cells

scientific article published on 24 February 2015

Neuronal autophagy, α-synuclein clearance, and LRRK2 regulation: a lost equilibrium in parkinsonian brain.

scientific article published in October 2012

Pressure effects on α-synuclein amyloid fibrils: An experimental investigation on their dissociation and reversible nature.

scientific article published on 14 June 2017

SARS-CoV-2-Mimicking Pseudoviral Particles Accelerate α-Synuclein Aggregation In Vitro

scientific article published in 2023

Superoxide Dismutases SOD1 and SOD2 Rescue the Toxic Effect of Dopamine-Derived Products in Human SH-SY5Y Neuroblastoma Cells

scientific article published on 21 June 2019

The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity

scientific article

Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies