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List of works by Klara Sjögren

A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I.

scientific article

Body Fat Content Can Be Predicted In Vivo in Mice Using a Modified Dual-Energy X-Ray Absorptiometry Technique

scientific article published on 01 November 2001

Body weight homeostat that regulates fat mass independently of leptin in rats and mice

scientific article published on 26 December 2017

Disproportional skeletal growth and markedly decreased bone mineral content in growth hormone receptor -/- mice.

scientific article

Effects of liver-derived insulin-like growth factor I on bone metabolism in mice

scientific article published in November 2002

Effects of the gut microbiota on bone mass

scientific article published on 9 December 2014

Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects

scientific article published in July 2009

Enzalutamide Reduces the Bone Mass in the Axial But Not the Appendicular Skeleton in Male Mice

scientific article published on 20 November 2015

Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2

scientific article

Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice

scientific article published on 23 January 2013

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.

scientific article published on February 2013

Estrogen up-regulates hepatic expression of suppressors of cytokine signaling-2 and -3 in vivo and in vitro

scientific article published on 19 August 2004

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits

scientific article published on 21 June 2016

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

scientific article published in January 2005

Growth hormone regulation of metabolic gene expression in muscle: a microarray study in hypopituitary men

scientific article published on 24 April 2007

Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice

scientific article published on 27 June 2017

Increased diet-induced fatty streak formation in female mice with deficiency of liver-derived insulin-like growth factor-I.

scientific article published on December 2015

Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult mice

scientific article published on 12 March 2018

Investigation of central versus peripheral effects of estradiol in ovariectomized mice

scientific article published in November 2005

Liver-derived IGF-I is of importance for normal carbohydrate and lipid metabolism.

scientific article

Liver-derived IGF-I regulates cortical bone mass but is dispensable for the osteogenic response to mechanical loading in female mice

scientific article published on 24 May 2016

Liver-derived IGF-I regulates exploratory activity in old mice

scientific article

Liver-derived IGF-I regulates kidney size, sodium reabsorption, and renal IGF-II expression

scientific article published on June 2007

Liver-derived IGF-I regulates mean life span in mice

scientific article (publication date: 2011)

Liver-derived IGF1 enhances the androgenic response in prostate

scientific journal article

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

scientific article

Liver-derived insulin-like growth factor-I is involved in the regulation of blood pressure in mice

scientific article published in November 2002

Metabolic functions of liver-derived (endocrine) insulin-like growth factor I.

scientific article published in January 2001

Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures

scientific article

Osteomicrobiology: A New Cross-Disciplinary Research Field

scientific article published on 27 October 2017

Probiotics protect mice from ovariectomy-induced cortical bone loss

scientific article

Reduced bone mass and muscle strength in male 5α-reductase type 1 inactivated mice

scientific article published in 2011

Regulation of bone mass by the gut microbiota is dependent on NOD1 and NOD2 signaling

scientific article

Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in bone.

scientific article

SERMs have substance-specific effects on bone, and these effects are mediated via ERαAF-1 in female mice

scientific article published on 05 April 2016

Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens

scientific article published on 13 December 2012

Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different pathways.

scientific article published on 30 April 2010

The bone-sparing effects of estrogen and WNT16 are independent of each other

scientific article

The estrogen receptor antagonist ICI 182,780 can act both as an agonist and an inverse agonist when estrogen receptor α AF-2 is modified

scientific article published on 06 January 2014

The gut microbiota regulates bone mass in mice

scientific article

The role of IGF-1 for fracture risk in men.

scientific article

The role of activation functions 1 and 2 of estrogen receptor-α for the effects of estradiol and selective estrogen receptor modulators in male mice

scientific article published on May 2013

The role of estrogen receptor α in growth plate cartilage for longitudinal bone growth

scientific article published on 18 June 2010

The role of liver-derived insulin-like growth factor-I.

scientific article published on 09 July 2009

The somatomedin hypothesis revisited in a transgenic model.

scientific article