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List of works by Alexander Greenhough

A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

scientific article published on 23 March 2020

A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer

scientific article published on 14 December 2020

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

scientific article

BAG-1 suppresses expression of the key regulatory cytokine transforming growth factor β (TGF-β1) in colorectal tumour cells

scientific article published on 29 October 2012

BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling

scientific article

BCL-3 promotes a cancer stem cell phenotype by enhancing β-catenin signalling in colorectal tumour cells

scientific article published on 04 March 2019

Cancer cell adaptation to hypoxia involves a HIF‐GPRC5A‐YAP axis

scientific article published on 01 November 2018

Cannabinoids and cancer: potential for colorectal cancer therapy: Table 1

article by Patsos HA et al published 1 August 2005 in Biochemical Society Transactions

Circulating prostaglandins as biomarkers for colorectal cancer?

scientific article published on 28 January 2015

Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation

scientific article published on 16 September 2011

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

scientific article

Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors

scientific article

LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells

scientific article published on 10 January 2019

LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity

scientific article published on 16 November 2017

LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs

scientific article published on 24 January 2013

LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma

scientific article

Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression.

scientific article published on 4 June 2018

Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways.

scientific article

Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.

scientific article published on 22 January 2015

Optimized delivery of siRNA into 3D tumor spheroid cultures in situ.

scientific article published on 21 May 2018

Protein arginine methyltransferase 5 is a key regulator of the MYCN oncoprotein in neuroblastoma cells

scientific article

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

scientific article published on 09 January 2009

The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells

scientific article

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2.

scientific article published on 11 August 2005

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.

scientific article published on 29 March 2010

Wnt Signaling Is a Major Determinant of Neuroblastoma Cell Lineages

scientific article published on 16 April 2019

Wnt Signalling Drives Context-Dependent Differentiation or Proliferation in Neuroblastoma

scientific article published on 2 March 2018

Wnt signalling drives context-dependent differentiation or proliferation in neuroblastoma

Wnt signalling is a major determinant of neuroblastoma cell lineages: Supplementary Figures 1-3

p16INK4a polymorphism: associations with tumour progression in patients with sporadic colorectal cancer

scientific article published on 01 November 2004

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

scientific article

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

scientific article

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