List of works - Anne Hamacher-Brady

A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria

scientific article published on September 2006

Agent-Based Modeling of Mitochondria Links Sub-Cellular Dynamics to Cellular Homeostasis and Heterogeneity

scientific article

Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

scientific article

Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila

scientific article (publication date: 2012)

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

scientific article

Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart.

scientific article

Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis.

scientific article published on 8 August 2015

Autophagy regulation and integration with cell signaling.

scientific article published on 25 January 2012

Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.

scientific article published in July 2015

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

scientific article

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.

scientific article published on 27 May 2015

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.

scientific article published on 3 July 2018

EMBO Workshop: Membrane Contact Sites in Health and Disease

scientific article published on 21 February 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Histone deacetylase 10 promotes autophagy-mediated cell survival.

scientific article published on 25 June 2013

Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

scientific article published on 2 May 2015

Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.

scientific article published on August 2014

Listeria monocytogenes virulence factors, including listeriolysin O, are secreted in biologically active extracellular vesicles

scientific article published on 30 November 2018

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling

scientific article

Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response

scientific article published on 18 December 2020

Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy

scientific article

Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis

scientific article published on 3 December 2012

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis

scientific article

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.

scientific article published on 25 April 2017

Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors.

scientific article published on 20 April 2006

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

scientific journal article

Systemic deregulation of autophagy upon loss of ALS- and FTD-linked C9orf72.

scientific article

The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores

scientific article published on June 2007

The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy.

scientific article published on December 2006

Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation

scientific article

List of works by Anne Hamacher-Brady

A wave of reactive oxygen species (ROS)-induced ROS release in a sea of excitable mitochondria

Agent-Based Modeling of Mitochondria Links Sub-Cellular Dynamics to Cellular Homeostasis and Heterogeneity

Agent-based modeling of autophagy reveals emergent regulatory behavior of spatio-temporal autophagy dynamics

Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart.

Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis.

Autophagy regulation and integration with cell signaling.

Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.

Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.

Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance.

EMBO Workshop: Membrane Contact Sites in Health and Disease

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Histone deacetylase 10 promotes autophagy-mediated cell survival.

Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.

Listeria monocytogenes virulence factors, including listeriolysin O, are secreted in biologically active extracellular vesicles

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling

Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response

Mitophagy programs: mechanisms and physiological implications of mitochondrial targeting by autophagy

Modulation of serines 17 and 24 in the LC3-interacting region of Bnip3 determines pro-survival mitophagy versus apoptosis

Multi-parametric analysis and modeling of relationships between mitochondrial morphology and apoptosis

Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.

Proapoptotic BCL-2 family members and mitochondrial dysfunction during ischemia/reperfusion injury, a study employing cardiac HL-1 cells and GFP biosensors.

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

Systemic deregulation of autophagy upon loss of ALS- and FTD-linked C9orf72.

The autophagic response to nutrient deprivation in the hl-1 cardiac myocyte is modulated by Bcl-2 and sarco/endoplasmic reticulum calcium stores

The interplay between pro-death and pro-survival signaling pathways in myocardial ischemia/reperfusion injury: apoptosis meets autophagy.

Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation