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List of works by Jacob Tfelt-Hansen

1alpha,25(OH)2-vitamin D3 inhibits HGF synthesis and secretion from MG-63 human osteosarcoma cells

scientific article published on 27 August 2002

A Common Variant in SCN5A and the Risk of Ventricular Fibrillation Caused by First ST-Segment Elevation Myocardial Infarction

scientific article

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression

scientific article published on 01 November 2018

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

scientific article published on 13 October 2009

A nationwide, retrospective analysis of symptoms, comorbidities, medical care and autopsy findings in cases of fatal pulmonary embolism in younger patients.

scientific article published on 21 May 2010

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

scientific article

Age of First Arrhythmic Event in Brugada Syndrome: Data From the SABRUS (Survey on Arrhythmic Events in Brugada Syndrome) in 678 Patients

scientific article published on 18 December 2017

Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

scientific article published on 07 January 2019

An International Multicenter Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition

scientific article published on 16 January 2020

Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

scientific article published on 01 October 2019

Association of common genetic variants related to atrial fibrillation and the risk of ventricular fibrillation in the setting of first ST-elevation myocardial infarction.

scientific article published on 21 November 2017

Burden of sudden cardiac death in persons aged 1 to 49 years: nationwide study in Denmark

scientific article published on 6 March 2014

Calcimimetic, AMG 073, induces relaxation on isolated rat aorta

scientific article published on 5 July 2007

Calcium acts as a first messenger through the calcium-sensing receptor in the cardiovascular system

scientific article published on 20 March 2007

Calcium and vitamin D3 supplements in calcium and vitamin D3 sufficient early postmenopausal healthy women.

scientific article published in October 2004

Calcium receptor expression and function in oligodendrocyte commitment and lineage progression: potential impact on reduced myelin basic protein in CaR-null mice

scientific article published in August 2008

Calcium receptor is functionally expressed in rat neonatal ventricular cardiomyocytes

scientific article published on 21 October 2005

Calcium-sensing receptor activation induces nitric oxide production in H-500 Leydig cancer cells

scientific article published on 18 January 2005

Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: role of epidermal growth factor receptor transactivation

scientific article published on September 2004

Calcium-sensing receptor induces messenger ribonucleic acid of human securin, pituitary tumor transforming gene, in rat testicular cancer.

scientific article published on 11 September 2003

Calcium-sensing receptor stimulates PTHrP release by pathways dependent on PKC, p38 MAPK, JNK, and ERK1/2 in H-500 cells

scientific article published on April 15, 2003

Calcium-sensing receptor stimulates secretion of an interferon-gamma-induced monokine (CXCL10) and monocyte chemoattractant protein-3 in immortalized GnRH neurons

scientific article published in March 2007

Cardiac Genetic Predisposition in Sudden Infant Death Syndrome

scientific article published on 01 March 2018

Cardiac arrhythmias in the emergency settings of acute coronary syndrome and revascularization: an European Heart Rhythm Association (EHRA) consensus document, endorsed by the European Association of Percutaneous Cardiovascular Interventions (EAPCI)

scientific article published on 01 October 2019

Cardiac channelopathies and sudden infant death syndrome

scientific article published on 16 July 2011

Cardiac symptoms before sudden cardiac death caused by coronary artery disease: a nationwide study among young Danish people

scientific article

Cardiac symptoms before sudden cardiac death caused by hypertrophic cardiomyopathy: a nationwide study among the young in Denmark

scientific article published on 27 January 2016

Cardiovascular screening for young athletes--reply

scientific article published on 01 April 2015

Characterization and Management of Arrhythmic Events in Young Patients With Brugada Syndrome

scientific article published on 01 April 2019

Circulating miRNAs and Risk of Sudden Death in Patients With Coronary Heart Disease

scientific article published on 30 October 2019

Common genetic variants and risk of ischemic heart failure: an evaluation of a negative genetic study

scientific article published on 13 February 2015

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scientific article

Comparison of hemodynamics, cardiac electrophysiology, and ventricular arrhythmia in an open- and a closed-chest porcine model of acute myocardial infarction

scientific article published on 10 January 2020

Continued misuse of orphan drug legislation: a life-threatening risk for mexiletine

scientific article published on 01 February 2020

Decline in incidence of sudden cardiac death in the young: a 10-year nationwide study of 8756 deaths in Denmark

scientific article published on 01 June 2019

Determinants of occurrence and survival after sudden cardiac arrest-A European perspective: The ESCAPE-NET project

scientific article published on 12 December 2017

Differences in clinical characteristics in patients with first ST-segment elevation myocardial infarction and ventricular fibrillation according to sex.

scientific article

Differences in investigations of sudden unexpected deaths in young people in a nationwide setting

scientific article

Diverse roles of extracellular calcium-sensing receptor in the central nervous system.

scientific article published on August 2010

Dysfunction of NaV1.4, a skeletal muscle voltage-gated sodium channel, in sudden infant death syndrome: a case-control study.

scientific article published on 5 April 2018

Editorial commentary: Sudden cardiac death prediction in the general population and among patients with left ventricular ejection fractions greater than 40

scientific article published on 29 May 2018

Effect of intermittent versus continuous parathyroid hormone in the cardiovascular system of rats

scientific article

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

scientific article published on 7 September 2020

Epidemiology and genetics of ventricular fibrillation during acute myocardial infarction

scientific article

Epilepsy and risk of death and sudden unexpected death in the young: a nationwide study.

scientific article published on 29 July 2013

Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scholarly article published in Nature Genetics

Ethnic differences in patients with Brugada syndrome and arrhythmic events: New insights from Survey on Arrhythmic Events in Brugada Syndrome

scientific article published on 05 July 2019

Exome data clouds the pathogenicity of genetic variants in Pulmonary Arterial Hypertension

scientific article published on 06 August 2018

Exome-Wide Rare Variant Analyses in Sudden Infant Death Syndrome

scientific article published on 26 September 2018

Expression of pituitary tumor transforming gene (PTTG) and its binding protein in human astrocytes and astrocytoma cells: function and regulation of PTTG in U87 astrocytoma cells

scientific article

Extracellular calcium sensing in rat aortic vascular smooth muscle cells

scientific article published on 7 August 2006

Factors Associated With and Outcomes After Ventricular Fibrillation Before and During Primary Angioplasty in Patients With ST-Segment Elevation Myocardial Infarction.

scientific article

Family History of Premature Death and Risk of Early Onset Cardiovascular Disease

article

Febrile seizures prior to sudden cardiac death: a Danish nationwide study

scientific article published on 23 November 2017

Fever-Related Arrhythmic Events in the Multicenter Survey on Arrhythmic Events in Brugada Syndrome (SABRUS).

scientific article published on 9 April 2018

Gender differences in patients with Brugada syndrome and arrhythmic events: Data from a survey on arrhythmic events in 678 patients

scientific article published on 13 June 2018

Gender differences in sudden cardiac death in the young-a nationwide study

scientific article

Genomic Triangulation in Sudden Unexplained Death in the Young: The Way to Go?

scientific article published in October 2017

Heritability in genetic heart disease: the role of genetic background

scientific article published on 28 May 2019

High calcium activates the EGF receptor potentially through the calcium-sensing receptor in Leydig cancer cells

scientific article published on June 2005

High prevalence of genetic variants previously associated with Brugada syndrome in new exome data.

scientific article

High-efficiency multiplex capillary electrophoresis single strand conformation polymorphism (multi-CE-SSCP) mutation screening of SCN5A: a rapid genetic approach to cardiac arrhythmia.

scientific article published in June 2006

How to prevent SCD in the young?

scientific article published on June 2017

Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest

scientific article published on 1 September 2019

Incidence and etiology of sports-related sudden cardiac death in Denmark--implications for preparticipation screening

scientific article published on 15 May 2010

Incidence and risk factors of ventricular fibrillation before primary angioplasty in patients with first ST-elevation myocardial infarction: a nationwide study in Denmark

scientific article

Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel

scientific article published on 20 October 2009

Insights into the genome-wide association studies of the electrocardiographic early repolarization pattern

scientific article published on 01 July 2012

Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

scientific article published on 21 February 2014

Is modification of the VVI backup mode in implantable cardioverter-defibrillators from St Jude medical required due to increased risk of inappropriate shocks?

scientific article published on 01 May 2017

Laboratory animal asthma in research workers

scientific article

Long QT syndrome is associated with an increased burden of diabetes, psychiatric and neurological comorbidities: a nationwide cohort study

scientific article published on 28 October 2019

Long-term proarrhythmic pharmacotherapy among patients with congenital long QT syndrome and risk of arrhythmia and mortality

scientific article published on 01 October 2019

Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation

scientific article published on 21 October 2019

Low disease prevalence and inappropriate implantable cardioverter defibrillator shock rate in Brugada syndrome: a nationwide study

scientific article published on 27 January 2012

Mitogenic action of calcium-sensing receptor on rat calvarial osteoblasts

scientific journal article

Mutations in genes encoding cardiac ion channels previously associated with sudden infant death syndrome (SIDS) are present with high frequency in new exome data

scientific article

Nationwide (Denmark) study of symptoms preceding sudden death due to arrhythmogenic right ventricular cardiomyopathy

scientific article published on 16 January 2014

Nationwide Study of Sudden Cardiac Death in People With Congenital Heart Defects Aged 0 to 35 Years

scientific article published on 01 June 2018

Nationwide study of sudden cardiac death in persons aged 1-35 years

scientific article published on 2 December 2010

New exome data question the pathogenicity of genetic variants previously associated with catecholaminergic polymorphic ventricular tachycardia

scientific article

New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome

scientific article

Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

scientific article

Next-generation sequencing using microfluidic PCR enrichment for molecular autopsy

scientific article published on 23 July 2019

Nitroglycerin headache and nitroglycerin-induced primary headaches from 1846 and onwards: a historical overview and an update

scientific article published on March 2009

Non-diagnostic autopsy findings in sudden unexplained death victims

scientific article published on 04 February 2020

Noncardiac genetic predisposition in sudden infant death syndrome

scientific article published on 24 August 2018

Novel role of the calcium-sensing receptor in blood pressure modulation

scientific article published on 27 October 2008

PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.

scientific article

Pacemaker implantation in a patient with brugada and sick sinus syndrome

scientific article published on March 2013

Perspectives on cardiovascular screening

scientific article

Pharmacokinetic Variability of Drugs Used for Prophylactic Treatment of Migraine

scientific article published on 12 April 2017

Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

scientific article published on 11 March 2017

Post-mortem toxicology in young sudden cardiac death victims: A nationwide cohort study

scientific article published on 27 February 2017

Potassium Disturbances and Risk of Ventricular Fibrillation Among Patients With ST-Segment-Elevation Myocardial Infarction

scientific article published on 12 February 2020

Precision cardiology

Precision of automated QRS duration measurement in patients treated with cardiac resynchronization therapy

scientific article published on 5 March 2018

Prior myocardial infarction in the young: predisposes to a high relative risk but low absolute risk of a sudden cardiac death

scientific article published on 28 June 2012

Profile of Brugada Syndrome Patients Presenting with Their First Documented Arrhythmic Event. Data from the Survey on Arrhythmic Events in BRUgada Syndrome (SABRUS).

scientific article published on 8 January 2018

Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

scientific article published on January 2017

Regulation of a Ca2+-activated K+ channel by calcium-sensing receptor involves p38 MAP kinase

scientific article published on February 2004

Risk factors and causes of sudden noncardiac death: A nationwide cohort study in Denmark

scientific article

Risk of cardiovascular disease in family members of young sudden cardiac death victims

scientific article

Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.

scientific article published on 17 February 2015

S-petasin and butterbur lactones dilate vessels through blockage of voltage gated calcium channels and block DNA synthesis

scientific article

SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation

article published in 2012

SCN5A mutations in 442 neonates and children: genotype-phenotype correlation and identification of higher-risk subgroups

scientific article published in August 2018

Seasonality of ventricular fibrillation at first myocardial infarction and association with viral exposure

scientific article published on 26 February 2020

Sibling history is associated with heart failure after a first myocardial infarction

scientific article published on 24 March 2020

Sick Sinus Syndrome, Progressive Cardiac Conduction Disease, Atrial Flutter and Ventricular Tachycardia Caused by a Novel SCN5A Mutation

article published in 2010

Sodium current and potassium transient outward current genes in Brugada syndrome: screening and bioinformatics

scientific article published on 28 January 2012

Specificity of Elevated Intercostal Space ECG Recording for the Type 1 Brugada ECG Pattern

scientific article published on 01 April 2012

Sports-related sudden cardiac death in a competitive and a noncompetitive athlete population aged 12 to 49 years: data from an unselected nationwide study in Denmark

scientific article

Sports-related sudden cardiac death: How to prove an effect of preparticipation screening?

scientific article published on 22 March 2016

Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

scientific article

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Successful reversal of life threatening cardiac effect following dosulepin overdose using intravenous lipid emulsion

scientific article published in April 2011

Sudden Cardiac Death in the Young

scientific article published on 12 December 2019

Sudden Cardiac Death: Pharmacotherapy and Proarrhythmic Drugs: A Nationwide Cohort Study in Denmark

scientific article published on 29 March 2017

Sudden cardiac death and coronary disease in the young: A nationwide cohort study in Denmark

scientific article published on 28 January 2017

Sudden cardiac death caused by myocarditis in persons aged 1-49 years: a nationwide study of 14 294 deaths in Denmark

scientific article published on 19 August 2019

Sudden cardiac death in children (1-18 years): symptoms and causes of death in a nationwide setting

scientific article published on 15 December 2013

Sudden cardiac death in young adults with previous hospital-based psychiatric inpatient and outpatient treatment: a nationwide cohort study from Denmark

scientific article

Sudden death in young persons with uncontrolled asthma--a nationwide cohort study in Denmark

scientific article published on 14 April 2015

Sudden unexpected death caused by stroke: A nationwide study among children and young adults in Denmark

scientific article

Sudden unexpected death in infancy in Denmark

scientific article published on 6 December 2010

Symptoms Before Sudden Arrhythmic Death Syndrome: A Nationwide Study Among the Young in Denmark

scientific article published on 12 May 2015

The Prevalence of Mutations inKCNQ1, KCNH2,andSCN5Ain an Unselected National Cohort of Young Sudden Unexplained Death Cases

article by BO GREGERS WINKEL et al published 6 August 2012 in Journal of Cardiovascular Electrophysiology

The calcium-sensing receptor and calcimimetics in blood pressure modulation

scientific article

The calcium-sensing receptor in human disease.

scientific article

The calcium-sensing receptor in normal physiology and pathophysiology: a review

scientific article

The emerging role of pituitary tumor transforming gene in tumorigenesis

scientific article

The human calcium-sensing receptor's role in illness and targets for therapy

scientific article published in May 2003

The pathogenicity of genetic variants previously associated with left ventricular non-compaction

scientific article published on 20 December 2015

The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary t

scientific article

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

The yield of postmortem genetic testing in sudden death cases with structural findings at autopsy

scientific article published on 18 September 2019

Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses

scientific article published on 22 August 2018

Time-to-first appropriate shock in patients implanted prophylactically with an implantable cardioverter-defibrillator: data from the Survey on Arrhythmic Events in BRUgada Syndrome (SABRUS)

scientific article published on 01 May 2019

Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome

scientific article

Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

scientific article published in March 2009

Verapamil for cluster headache. Clinical pharmacology and possible mode of action

scientific article published on January 2009

Virus infection as a trigger for sudden cardiac arrest

scientific article published on 01 July 2018

Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

scientific article

[Catecholaminergic polymorphic ventricular tachycardia is a rare inherited heart disease].

scientific article published in August 2010

[Dynamic ECG changes as a result of Brugada syndrome, an overlooked diagnosis?]

scientific article published on 01 August 2005

[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations]

scientific article published on 01 April 2009

[New European randomized placebo-controlled study casts doubt on the use of nicotinic acid in the treatment of familial hypercholesterolemia]

[Parathyroid hormone-related peptide induced humoral hypercalcemia of malignancy]

scientific article published on 01 February 2005

[Sudden unexpected cardiac death in an 18-year-old female with familial hypercholesterolaemia]

[The genome and cardiology]

scientific article published on 01 November 2014

[Transcripts from automated external defibrillator are important]

scientific article published in January 2014