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List of works by Frederick Alt

A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency.

scientific article

An Ectopic CTCF Binding Element Inhibits Tcrd Rearrangement by Limiting Contact between Vδ and Dδ Gene Segments

scientific article published on 9 September 2016

BCR selection and affinity maturation in Peyer's patch germinal centres

scientific article published on 06 May 2020

C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency

scientific article published on 26 April 2022

CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning

scientific article published on 27 July 2020

Direct analysis of brain phenotypes via neural blastocyst complementation

scientific article published on 10 August 2020

Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency

scientific article

Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor Antibodies

scientific article published on 31 July 2018

Immune checkpoint modulation enhances HIV-1 antibody induction

scientific article published on 19 February 2020

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

scientific article published on September 2016

Loop extrusion mediates physiological Igh locus contraction for RAG scanning

scientific article published on 13 January 2021

Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development

scientific article published on 15 August 2016

Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies

scientific article

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

scientific article

The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity

scientific article published on 15 February 2024

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