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List of works by Frederic Y. Bois

A computational model to predict rat ovarian steroid secretion from in vitro experiments with endocrine disruptors

scientific article published in 2013

A group sequential approach to crossover trials for average bioequivalence

scientific article published in March 1997

A parametric approach to population bioequivalence

scientific article published in February 1997

Absorption rate vs. exposure: which is more useful for bioequivalence testing?

scientific article published in March 1996

Addressing human variability in next-generation human health risk assessments of environmental chemicals

scientific article

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

scientific article

An analysis of exposure rate effects for benzene using a physiologically based pharmacokinetic model

scientific article

Analysis of PBPK models for risk characterization

scientific article

Application of clearance concepts to the assessment of exposure to lead in drinking water

scientific article published on 01 July 1989

Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress

scientific article published on 10 December 2012

Applications of population approaches in toxicology

scientific article published in March 2001

Assessing the reliability of PBPK models using data from methyl chloride-exposed, non-conjugating human subjects.

scientific article

Bacterial Inoculum Density and Probability of para-Nitrophenol Biodegradability Test Response

article

Bayesian analysis of an epidemiologic model of Plasmodium falciparum malaria infection in Ndiop, Senegal

scientific article published in October 2000

Bayesian inference

scientific article published on January 2013

Bioequivalence: performance of several measures of extent of absorption

scientific article published in May 1994

Bioequivalence: performance of several measures of rate of absorption

scientific article published on 01 July 1994

Characterizing uncertainty and variability in physiologically based pharmacokinetic models: state of the science and needs for research and implementation

scientific article published on 4 May 2007

Choice of student's t- or Wilcoxon-based confidence intervals for assessment of average bioequivalence

scientific article

Comparison of three physiologically based pharmacokinetic models of benzene disposition

scientific article published in August 1991

Considerations in the attainment of steady state: aggregate vs. individual assessment

scientific article published on 01 November 1998

Decrease in ovalbumin-induced pulmonary allergic response by benzaldehyde but not acetaldehyde exposure in a Guinea pig model

scientific article

Development of a physiologically based kinetic model for 99m-technetium-labelled carbon nanoparticles inhaled by humans

scientific article published in November 2009

Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues

journal article published in 2007

Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: the first steps

scientific article published on February 2008

Environmental benzene exposure assessment for parent-child pairs in Rouen, France.

scientific article published in June 2003

Evaluation of antiangiogenic treatment effects on tumors' microcirculation by Bayesian physiological pharmacokinetic modeling and magnetic resonance imaging.

scientific article published on 23 May 2006

Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats

scientific article published in March 2004

GNU MCSim: Bayesian statistical inference for SBML-coded systems biology models

scientific article published on 20 March 2009

Genetic and dietary factors affecting human metabolism of 1,3-butadiene.

scientific article published in June 2001

Ignoring and adding errors do not improve the science.

scientific article published on 25 March 2013

Interspecies extrapolation of physiological pharmacokinetic parameter distributions

scientific article

Interspecies extrapolation: a reexamination of acute toxicity data

scientific article

Intratracheal instillation of cytoplasmic granules from Phleum pratense pollen induces IgE- and cell-mediated responses in the Brown Norway rat.

scientific article published on 29 July 2004

Low-dose metabolism of benzene in humans: science and obfuscation

scientific article published on 7 December 2012

Lumping in pharmacokinetics.

scientific article

Mechanisms of benzene carcinogenesis: application of a physiological model of benzene pharmacokinetics and metabolism

scientific article

Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making

journal article published in 2008

Modeling benzene pharmacokinetics across three sets of animal data: parametric sensitivity and risk implications

scientific article

Modeling human interindividual variability in metabolism and risk: the example of 4-aminobiphenyl

scientific article published in April 1995

Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats

scientific article

Multiscale modelling approaches for assessing cosmetic ingredients safety.

scientific article

Occupational Exposure to Cobalt: A Population Toxicokinetic Modeling Approach Validated by Field Results Challenges the Biological Exposure Index for Urinary Cobalt

scientific article published on 01 January 2010

Optimal design for a study of butadiene toxicokinetics in humans

scientific article published on June 1999

Optimization issues in physiological toxicokinetic modeling: a case study with benzene.

scientific article published in August 1993

PBPK modelling of inter-individual variability in the pharmacokinetics of environmental chemicals

scientific article

Pharmacokinetic concepts in assessing intake of pentachlorophenol by rats after exposure through drinking water

scientific article published on November 1992

Pharmacokinetic-pharmacodynamic models for categorical toxicity data

scientific article

Phleum pratense pollen starch granules induce humoral and cell-mediated immune responses in a rat model of allergy

scientific article published in February 2004

Physiologically based modelling and prediction of drug interactions

scientific article

Physiologically based pharmacokinetic modeling of inhalation exposure of humans to dichloromethane during moderate to heavy exercise

scientific article

Precision and sensitivity of pharmacokinetic models for cancer risk assessment: tetrachloroethylene in mice, rats, and humans

scientific article published in February 1990

Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury

scientific article published on 24 December 2011

Propylene glycol monomethyl ether. A three-generation study of isomer beta effects on reproductive and developmental parameters in rats

scientific article published in March 2005

Quantifying heterogeneity in exposure-risk relationships using exhaled breath biomarkers for 1,3-butadiene exposures

scientific article

Revisiting the population toxicokinetics of tetrachloroethylene

scientific article published on 11 February 2006

Screening blood donations for hepatitis C in Central Africa: analysis of a risk- and cost-based decision tree

scientific article published in July 1999

Sensitivity analysis of a new model of carcinogenesis

article

Sequential updating of a new dynamic pharmacokinetic model for caffeine in premature neonates

scientific article published in January 2007

Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics

scientific article

Statistical analysis of Fisher et al. PBPK model of trichloroethylene kinetics

scientific article

Stochasticity in physiologically based kinetics models: implications for cancer risk assessment.

scientific article

Structure and parameterization of pharmacokinetic models: their impact on model predictions

scientific article published in June 1992

The application of a Bayesian approach to the analysis of a complex, mechanistically based model

scientific article published in January 2007

Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches

scientific article published on 04 July 2012

Toxicokinetics of inhaled trichloroethylene and tetrachloroethylene in humans at 1 ppm: empirical results and comparisons with previous studies

scientific article published on 10 October 2006

Use of a chemical probe to increase safety for human volunteers in toxicokinetic studies

scientific article published in December 2005

Well-tempered MCMC simulations for population pharmacokinetic models

scientific article published on 31 July 2020

Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions

scientific article

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