List of works - Dazhong Xu

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

scientific article

MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation

scientific article

Combined Measurement of the Higgs Boson Mass in p p Collisions at √s=7 and 8 TeV with the ATLAS and CMS Experiments

scientific article

HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury

scientific article published on August 5, 2010

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

scientific article

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

scientific article

Covalent modifications of histones during mitosis and meiosis.

scientific article

Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain

scientific article

Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model

scientific article published on 01 May 2006

Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha

scientific article

Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury

scientific article published on December 23, 2010

Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway.

scientific article published in November 2007

Nitric oxide directly impairs intestinal barrier function.

scientific article published on February 2002

Lipopolysaccharide-induced enterocyte-derived nitric oxide induces intestinal monolayer permeability in an autocrine fashion.

scientific article published in March 2002

Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

scientific article published on September 2004

Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock

scientific article published in April 2006

Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products.

scientific article

Regulation of PTEN Stability and Activity by Plk3

scientific article published on October 12, 2010

Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation.

scientific article

A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines

scientific article published on 01 July 2004

Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity

scientific article published on 01 May 2005

Hydrophobicity of mucosal surface and its relationship to gut barrier function

scientific article published on 01 March 2008

Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation

scientific article published on 01 December 2002

Shock mesenteric lymph-induced rat polymorphonuclear neutrophil activation and endothelial cell injury is mediated by aqueous factors.

scientific article

Mesenteric lymph duct ligation improves survival in a lethal shock model

scientific article published on 01 December 2008

Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells

scientific article published on 01 June 2002

Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.

scientific article published in February 1998

Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms.

scientific article

Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.

scientific article published on July 2006

Loss of the Intestinal Mucus Layer in the Normal Rat Causes Gut Injury But Not Toxic Mesenteric Lymph nor Lung Injury

scientific article published on November 1, 2010

The Anatomic Sites of Disruption of the Mucus Layer Directly Correlate With Areas of Trauma/Hemorrhagic Shock-Induced Gut Injury

scientific article published on March 1, 2011

Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.

scientific article published on August 2010

Estrogen Receptor Hormone Agonists Limit Trauma Hemorrhage Shock-Induced Gut and Lung Injury in Rats

scientific article published on February 25, 2010

Hemorrhagic shock induces endothelial cell apoptosis, which is mediated by factors contained in mesenteric lymph.

scientific article published in December 2004

Albumin peptide: a molecular marker for trauma/hemorrhagic-shock in rat mesenteric lymph

scientific article published on 08 June 2005

Lymph from a primate baboon trauma hemorrhagic shock model activates human neutrophils

scientific article published on 01 May 2006

Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition.

scientific article

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.

scientific article published on August 2012

Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat

scientific article published on 01 September 2003

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.

scientific article published on 18 April 2012

Recombinant Factor XIII Mitigates Hemorrhagic Shock-Induced Organ Dysfunction

scientific article published on December 31, 2010

Effect of trauma-hemorrhagic shock on red blood cell deformability and shape

scientific article published on 01 March 2003

Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression

scientific article

Intravenous Injection of Mesenteric Lymph Produced During Hemorrhagic Shock Decreases RBC Deformability in the Rat

scientific article published on February 1, 2011

Elimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.

scientific article

Albumin protects against gut-induced lung injury in vitro and in vivo.

scientific article published in August 2004

Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma

scientific article

Amiloride moderates increased gut permeability and diminishes mesenteric lymph-mediated priming of neutrophils in trauma/hemorrhagic shock

scientific article published on 28 August 2006

Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone.

scientific article published in November 2005

Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injury.

scientific article published in July 2008

List of works by Dazhong Xu

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation

Combined Measurement of the Higgs Boson Mass in p p Collisions at √s=7 and 8 TeV with the ATLAS and CMS Experiments

HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

Covalent modifications of histones during mitosis and meiosis.

Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain

Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model

Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha

Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury

Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway.

Nitric oxide directly impairs intestinal barrier function.

Lipopolysaccharide-induced enterocyte-derived nitric oxide induces intestinal monolayer permeability in an autocrine fashion.

Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock

Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products.

Regulation of PTEN Stability and Activity by Plk3

Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation.

A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines

Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity

Hydrophobicity of mucosal surface and its relationship to gut barrier function

Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation

Shock mesenteric lymph-induced rat polymorphonuclear neutrophil activation and endothelial cell injury is mediated by aqueous factors.

Mesenteric lymph duct ligation improves survival in a lethal shock model

Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells

Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.

Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms.

Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.

Loss of the Intestinal Mucus Layer in the Normal Rat Causes Gut Injury But Not Toxic Mesenteric Lymph nor Lung Injury

The Anatomic Sites of Disruption of the Mucus Layer Directly Correlate With Areas of Trauma/Hemorrhagic Shock-Induced Gut Injury

Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.

Estrogen Receptor Hormone Agonists Limit Trauma Hemorrhage Shock-Induced Gut and Lung Injury in Rats

Hemorrhagic shock induces endothelial cell apoptosis, which is mediated by factors contained in mesenteric lymph.

Albumin peptide: a molecular marker for trauma/hemorrhagic-shock in rat mesenteric lymph

Lymph from a primate baboon trauma hemorrhagic shock model activates human neutrophils

Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition.

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.

Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.

Recombinant Factor XIII Mitigates Hemorrhagic Shock-Induced Organ Dysfunction

Effect of trauma-hemorrhagic shock on red blood cell deformability and shape

Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression

Intravenous Injection of Mesenteric Lymph Produced During Hemorrhagic Shock Decreases RBC Deformability in the Rat

Elimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.

Albumin protects against gut-induced lung injury in vitro and in vivo.

Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma

Amiloride moderates increased gut permeability and diminishes mesenteric lymph-mediated priming of neutrophils in trauma/hemorrhagic shock

Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone.

Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injury.