List of works - Dazhong Xu

A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines

scientific article published on 01 July 2004

Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock

scientific article published in April 2006

Albumin peptide: a molecular marker for trauma/hemorrhagic-shock in rat mesenteric lymph

scientific article published on 08 June 2005

Albumin protects against gut-induced lung injury in vitro and in vivo.

scientific article published in August 2004

Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone.

scientific article published in November 2005

Amiloride moderates increased gut permeability and diminishes mesenteric lymph-mediated priming of neutrophils in trauma/hemorrhagic shock

scientific article published on 28 August 2006

Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma

scientific article

Anticoagulants Influence the In Vitro Activity and Composition of Shock Lymph But Not Its In Vivo Activity ⬇️

scientific article published on August 1, 2011

Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression

scientific article

Burn-induced red blood cell deformability and shape changes are modulated by sex hormones.

scientific article

Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injury.

scientific article published in July 2008

Cellular mechanisms of burn-related changes in contractility and its prevention by mesenteric lymph ligation

scientific article published on 19 January 2007

Combined Measurement of the Higgs Boson Mass in p p Collisions at √s=7 and 8 TeV with the ATLAS and CMS Experiments ⬇️

scientific article

Covalent modifications of histones during mitosis and meiosis.

scientific article

Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain

scientific article

Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

scientific article published on 01 December 2019

Dual effects of mesenteric lymph isolated from rats with burn injury on contractile function in rat ventricular myocytes

scientific article published on 07 October 2005

Ectopic bone formation using osteogenic protein-1 carried by a solution precipitated hydroxyapatite

scientific article published on 01 December 2004

Effect of trauma-hemorrhagic shock on red blood cell deformability and shape

scientific article published on 01 March 2003

Elimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.

scientific article

Enhancing bone marrow regeneration by SALL4 protein

scientific article published on 5 November 2013

Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.

scientific article published on August 2010

Female sex hormones protect red blood cells from damage after trauma-hemorrhagic shock.

scientific article published in January 2004

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

scientific article

Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.

scientific article published on July 2006

Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat

scientific article published on 01 September 2003

Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model

scientific article published on 01 May 2006

HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury ⬇️

scientific article published on August 5, 2010

Hemorrhagic shock induces endothelial cell apoptosis, which is mediated by factors contained in mesenteric lymph.

scientific article published in December 2004

Hydrophobicity of mucosal surface and its relationship to gut barrier function

scientific article published on 01 March 2008

Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury ⬇️

scientific article published on December 23, 2010

Intestinal bacterial overgrowth induces the production of biologically active intestinal lymph

scientific article published in January 2004

Intravenous Injection of Mesenteric Lymph Produced During Hemorrhagic Shock Decreases RBC Deformability in the Rat ⬇️

scientific article published on February 1, 2011

Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway.

scientific article published in November 2007

Isolation, culture and characterization of endothelial cells from human hypertrophic scar

scientific article published on 01 May 2008

Lipopolysaccharide-induced enterocyte-derived nitric oxide induces intestinal monolayer permeability in an autocrine fashion.

scientific article published in March 2002

Lymph from a primate baboon trauma hemorrhagic shock model activates human neutrophils

scientific article published on 01 May 2006

Mesenteric Lymph From Rats With Thermal Injury Prolongs the Action Potential and Increases Ca2+ Transient in Rat Ventricular Myocytes ⬇️

scientific article published on November 1, 2003

Mesenteric lymph duct ligation improves survival in a lethal shock model

scientific article published on 01 December 2008

MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation

scientific article

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

scientific article

Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel

scientific article published on 17 May 2017

Na+,K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide.

scientific article

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

scientific article

Nitric oxide directly impairs intestinal barrier function.

scientific article published on February 2002

Nuclear protein IK undergoes dynamic subcellular translocation and forms unique nuclear bodies during the cell cycle

scientific article

Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

scientific article published on September 2004

Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products.

scientific article

Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha

scientific article

Polo-like kinase 3, hypoxic responses, and tumorigenesis.

scientific article published on 31 August 2017

Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.

scientific article published in February 1998

Recombinant Factor XIII Mitigates Hemorrhagic Shock-Induced Organ Dysfunction ⬇️

scientific article published on December 31, 2010

Regulation of PTEN Stability and Activity by Plk3 ⬇️

scientific article published on October 12, 2010

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.

scientific article published on 18 April 2012

Sexual dimorphism in the activation of neutrophils by shock mesenteric lymph

scientific article published on January 2003

Shock mesenteric lymph-induced rat polymorphonuclear neutrophil activation and endothelial cell injury is mediated by aqueous factors.

scientific article

Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition.

scientific article

Systemic Inflammatory Response Does Not Correlate with Acute Lung Injury Associated with Mechanical Ventilation Strategies in Normal Lungs ⬇️

scientific article published on May 14, 2012

The Anatomic Sites of Disruption of the Mucus Layer Directly Correlate With Areas of Trauma/Hemorrhagic Shock-Induced Gut Injury ⬇️

scientific article published on March 1, 2011

Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation.

scientific article published on 19 October 2017

Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation

scientific article published on 01 December 2002

Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity

scientific article published on 01 May 2005

Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms.

scientific article

Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation.

scientific article

Trauma-shock-induced gut injury and the production of biologically active intestinal lymph is abrogated by castration in a large animal porcine model

scientific article published on 01 August 2008

Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells

scientific article published on 01 June 2002

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.

scientific article published on August 2012

List of works by Dazhong Xu

A study of the biologic activity of trauma-hemorrhagic shock mesenteric lymph over time and the relative role of cytokines

Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock

Albumin peptide: a molecular marker for trauma/hemorrhagic-shock in rat mesenteric lymph

Albumin protects against gut-induced lung injury in vitro and in vivo.

Amiloride combined with small-volume resuscitation with hypertonic saline is superior in ameliorating trauma-hemorrhagic shock-induced lung injury in rats to the administration of either agent alone.

Amiloride moderates increased gut permeability and diminishes mesenteric lymph-mediated priming of neutrophils in trauma/hemorrhagic shock

Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma

Anticoagulants Influence the In Vitro Activity and Composition of Shock Lymph But Not Its In Vivo Activity ⬇️

Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression

Burn-induced red blood cell deformability and shape changes are modulated by sex hormones.

Calcium entry inhibition during resuscitation from shock attenuates inflammatory lung injury.

Cellular mechanisms of burn-related changes in contractility and its prevention by mesenteric lymph ligation

Combined Measurement of the Higgs Boson Mass in p p Collisions at √s=7 and 8 TeV with the ATLAS and CMS Experiments ⬇️

Covalent modifications of histones during mitosis and meiosis.

Defective Rac-mediated proliferation and survival after targeted mutation of the beta1 integrin cytodomain

Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer

Dual effects of mesenteric lymph isolated from rats with burn injury on contractile function in rat ventricular myocytes

Ectopic bone formation using osteogenic protein-1 carried by a solution precipitated hydroxyapatite

Effect of trauma-hemorrhagic shock on red blood cell deformability and shape

Elimination of C5aR prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.

Enhancing bone marrow regeneration by SALL4 protein

Ethyl pyruvate prevents inflammatory responses and organ damage during resuscitation in porcine hemorrhage.

Female sex hormones protect red blood cells from damage after trauma-hemorrhagic shock.

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling.

Gut injury and gut-induced lung injury after trauma hemorrhagic shock is gender and estrus cycle specific in the rat

Gut-lymph hypothesis of systemic inflammatory response syndrome/multiple-organ dysfunction syndrome: validating studies in a porcine model

HIF-1 mediates pathogenic inflammatory responses to intestinal ischemia-reperfusion injury ⬇️

Hemorrhagic shock induces endothelial cell apoptosis, which is mediated by factors contained in mesenteric lymph.

Hydrophobicity of mucosal surface and its relationship to gut barrier function

Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury ⬇️

Intestinal bacterial overgrowth induces the production of biologically active intestinal lymph

Intravenous Injection of Mesenteric Lymph Produced During Hemorrhagic Shock Decreases RBC Deformability in the Rat ⬇️

Intravenous injection of trauma-hemorrhagic shock mesenteric lymph causes lung injury that is dependent upon activation of the inducible nitric oxide synthase pathway.

Isolation, culture and characterization of endothelial cells from human hypertrophic scar

Lipopolysaccharide-induced enterocyte-derived nitric oxide induces intestinal monolayer permeability in an autocrine fashion.

Lymph from a primate baboon trauma hemorrhagic shock model activates human neutrophils

Mesenteric Lymph From Rats With Thermal Injury Prolongs the Action Potential and Increases Ca2+ Transient in Rat Ventricular Myocytes ⬇️

Mesenteric lymph duct ligation improves survival in a lethal shock model

MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel

Na+,K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide.

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

Nitric oxide directly impairs intestinal barrier function.

Nuclear protein IK undergoes dynamic subcellular translocation and forms unique nuclear bodies during the cell cycle

Persistent HIF-1alpha activation in gut ischemia/reperfusion injury: potential role of bacteria and lipopolysaccharide.

Phosphatidylinositol 3'-kinase-dependent activation of renal mesangial cell Ki-Ras and ERK by advanced glycation end products.

Plk3 functions as an essential component of the hypoxia regulatory pathway by direct phosphorylation of HIF-1alpha

Polo-like kinase 3, hypoxic responses, and tumorigenesis.

Protective effect on Leishmania major infection of migration inhibitory factor, TNF-alpha, and IFN-gamma administered orally via attenuated Salmonella typhimurium.

Recombinant Factor XIII Mitigates Hemorrhagic Shock-Induced Organ Dysfunction ⬇️

Regulation of PTEN Stability and Activity by Plk3 ⬇️

Roles of Polo-like kinase 3 in suppressing tumor angiogenesis.

Sexual dimorphism in the activation of neutrophils by shock mesenteric lymph

Shock mesenteric lymph-induced rat polymorphonuclear neutrophil activation and endothelial cell injury is mediated by aqueous factors.

Small volume resuscitation with hypertonic saline is more effective in ameliorating trauma-hemorrhagic shock-induced lung injury, neutrophil activation and red blood cell dysfunction than pancreatitic protease inhibition.

Systemic Inflammatory Response Does Not Correlate with Acute Lung Injury Associated with Mechanical Ventilation Strategies in Normal Lungs ⬇️

The Anatomic Sites of Disruption of the Mucus Layer Directly Correlate With Areas of Trauma/Hemorrhagic Shock-Induced Gut Injury ⬇️

Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation.

Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation

Trauma-hemorrhagic shock mesenteric lymph from rat contains a modified form of albumin that is implicated in endothelial cell toxicity

Trauma-hemorrhagic shock mesenteric lymph induces endothelial apoptosis that involves both caspase-dependent and caspase-independent mechanisms.

Trauma-hemorrhagic shock-induced up-regulation of endothelial cell adhesion molecules is blunted by mesenteric lymph duct ligation.

Trauma-shock-induced gut injury and the production of biologically active intestinal lymph is abrogated by castration in a large animal porcine model

Trauma/hemorrhagic shock mesenteric lymph upregulates adhesion molecule expression and IL-6 production in human umbilical vein endothelial cells

Vagal nerve stimulation modulates gut injury and lung permeability in trauma-hemorrhagic shock.