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List of works by Hiroaki Yamaguchi

A Case of Renal Cell Carcinoma with High Everolimus Blood Concentrations and Hyperglycemia Due to Everolimus-Induced Hepatic Dysfunction

scientific article published in January 2017

A full validated hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the quantification of oxaliplatin in human plasma ultrafiltrates

scientific article published on 17 August 2012

A novel extraction method based on a reversible chemical conversion for the LC/MS/MS analysis of the stable organic germanium compound Ge-132

scientific article published on 28 January 2015

A rapid and sensitive LC/ESI-MS/MS method for quantitative analysis of docetaxel in human plasma and its application to a pharmacokinetic study

scientific article published on 09 February 2012

A simultaneous determination method for 5-fluorouracil and its metabolites in human plasma with linear range adjusted by in-source collision-induced dissociation using hydrophilic interaction liquid chromatography-electrospray ionization-tandem mass

scientific article

Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis

scientific article published on 12 July 2019

An accurate quantitative LC/ESI–MS/MS method for sirolimus in human whole blood ⬇️

scientific article published on March 12, 2011

Analysis of membrane transport mechanisms of endogenous substrates using chromatographic techniques

scientific article published on 20 February 2019

Analysis of phosphorylated peptides by double pseudoneutral loss extraction coupled with derivatization using N-(4-bromobenzoyl)aminoethanethiol

scientific article published in November 2009

Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides.

scientific article published on 2 September 2008

Crucial Residue Involved in L-Lactate Recognition by Human Monocarboxylate Transporter 4 (hMCT4) ⬇️

scientific article published on July 31, 2013

Determination of chlorhexidine (CHD) and nonylphenolethoxylates (NPEOn) using LC-ESI-MS method and application to hemolyzed blood.

scientific article published on 27 December 2005

Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS.

scientific article

Development of a Liquid Chromatography-Tandem Mass Spectrometric Method for Quantification of Mycophenolic Acid and Its Glucuronides in Dried Blood Spot Samples

scientific article published on 14 October 2017

Development of a precise quantitative method for monitoring sirolimus in whole blood using LC/ESI-MS/MS

scientific article published on 17 April 2020

Effect of cisplatin-induced acute renal failure on bioavailability and intestinal secretion of quinolone antibacterial drugs in rats.

scientific article published in February 2004

Erratum to: Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS

scientific article published on 24 February 2015

Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with Niemann-Pick disease type C and 3β-hydroxysteroid dehydrogenase deficienc

scientific article published on 9 January 2015

Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.

scientific article published on 14 December 2016

Functional characterization of 21 allelic variants of dihydropyrimidinase.

scientific article published on 19 June 2017

Functional characterization of 9 CYP2A13 allelic variants by assessment of nicotine C-oxidation and coumarin 7-hydroxylation.

scientific article published on 22 November 2017

Identification and elimination of ion suppression in the quantitative analysis of sirolimus in human blood by LC/ESI-MS/MS

scientific article published on 22 March 2011

Identification of Two Sulfated Cholesterol Metabolites Found in the Urine of a Patient with Niemann-Pick Disease Type C as Novel Candidate Diagnostic Markers.

scientific article published on 25 November 2016

Impact of clinical factors and UGT1A9 and CYP2B6 genotype on inter-individual differences in propofol pharmacokinetics.

scientific article published on 21 February 2018

Interactions of crizotinib and gefitinib with organic anion-transporting polypeptides (OATP)1B1, OATP1B3 and OATP2B1: gefitinib shows contradictory interaction with OATP1B3.

scientific article published on 22 December 2016

Intestinal Ischemia-Reperfusion Increases Efflux for Uric Acid Via Paracellular Route in the Intestine, but Decreases that Via Transcellular Route Mediated by BCRP ⬇️

scientific article published on January 1, 2012

LC/ESI-MS/MS analysis of urinary 3β-sulfooxy-7β-N-acetylglucosaminyl-5-cholen-24-oic acid and its amides: New biomarkers for the detection of Niemann–Pick type C disease ⬇️

scientific article published on 07 June 2013

Long-term relationship between everolimus blood concentration and clinical outcomes in Japanese patients with metastatic renal cell carcinoma: a prospective study

scientific article published on 12 March 2019

Matrix effect-corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine

scientific article published on 06 March 2017

Microdetermination of the 6,15-diketo-13,14-dihydroprostaglandin F1alpha in human plasma using gas chromatography/selected ion monitoring with [18O]6,15-diketo-13,14-dihydro-prostaglandin F1alpha as an internal standard

scientific article published on 01 October 1999

Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases.

scientific article

Mitochonic Acid 5 (MA-5), a Derivative of the Plant Hormone Indole-3-Acetic Acid, Improves Survival of Fibroblasts from Patients with Mitochondrial Diseases.

scientific article published on January 2015

Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage

scientific article published on 25 November 2015

Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts

scientific article published on 20 September 2019

Plasma mycophenolic acid concentration and the clinical outcome after lung transplantation

scientific article published on 19 September 2020

Potential Drug Interactions Mediated by Renal Organic Anion Transporter OATP4C1.

scientific article

Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3.

scientific article

Preparation of neocarzinostatin apoprotein mutants and the randomized library on the chromophore-binding cavity

scientific article published in May 2006

Production of 18O-single labeled peptide fragments during trypsin digestion of proteins for quantitative proteomics using nanoLC-ESI-MS/MS.

scientific article published in July 2010

Quantification of intact carboplatin in human plasma ultrafitrates using hydrophilic interaction liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study ⬇️

scientific article published on December 3, 2012

Quantitative determination of paclitaxel and its metabolites, 6α‐hydroxypaclitaxel and p‐3′‐hydroxypaclitaxel, in human plasma using column‐switching liquid chromatography/tandem mass spectrometry ⬇️

scientific article published on September 27, 2012

Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.

scientific article

Regulation of human monocarboxylate transporter 4 in skeletal muscle cells: The role of protein kinase C (PKC) ⬇️

scientific article published on March 9, 2012

Regulation of multidrug resistance protein 2 (MRP2, ABCC2) expression by statins: Involvement of SREBP-mediated gene regulation ⬇️

scientific article published on April 20, 2013

Renal Uptake of Substrates for Organic Anion Transporters Oat1 and Oat3 and Organic Cation Transporters Oct1 and Oct2 is Altered in Rats with Adenine-Induced Chronic Renal Failure ⬇️

scientific article published on December 29, 2012

Screening of antibiotics that interact with organic anion-transporting polypeptides 1B1 and 1B3 using fluorescent probes

scientific article published on 01 January 2011

Severe toxicity induced by accumulation of active sunitinib metabolite in a Japanese patient with renal cell carcinoma: a case report

scientific article

Shifting the Linear Range in Electrospray Ionization by In-Source Collision-Induced Dissociation

scientific article published on 01 January 2016

Simple quantification of lansoprazole and rabeprazole concentrations in human serum by liquid chromatography/tandem mass spectrometry.

scientific article published on 12 June 2008

Simultaneous analysis of oral anticancer drugs for renal cell carcinoma in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry

scientific article published on 28 December 2017

Simultaneous quantification of seven prostanoids using liquid chromatography/tandem mass spectrometry: the effects of arachidonic acid on prostanoid production in mouse bone marrow-derived mast cells

scientific article published on 21 June 2007

Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry.

scientific article

Structural Determination of Lysosphingomyelin-509 and Discovery of Novel Class Lipids from Patients with Niemann-Pick Disease Type C

scientific article published on 10 October 2019

Successful Colistin Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infection Using a Rapid Method for Determination of Colistin in Plasma: Usefulness of Therapeutic Drug Monitoring

scientific article published on 9 July 2015

The Decrease in Farnesoid X Receptor, Pregnane X Receptor and Constitutive Androstane Receptor in the Liver after Intestinal Ischemia-Reperfusion ⬇️

scientific article published on January 1, 2012

Transport characteristics of grepafloxacin and levofloxacin in the human intestinal cell line Caco-2 ⬇️

scientific article published on November 23, 2001

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

scientific article published on 13 March 2006

cGMP transport by vesicles from human and mouse erythrocytes

scientific article published on 01 January 2007

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