Search filters

List of works by Melanie J. McConnell

A combination of tyrosine kinase inhibitors, crizotinib and dasatinib for the treatment of glioblastoma multiforme.

scientific article

Ascorbate combination therapy: new tool in the anticancer toolbox?

scientific article published on 01 February 2014

Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC

scientific article

ET-39REPEATED PHARMACOLOGICAL DOSES OF ASCORBATE PROTECTS TUMOURS FROM RADIATION DAMAGE IN AN INTRACRANIAL MOUSE GLIOMA MODEL.

scientific article published in November 2014

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

scientific article published on 22 June 2009

Enhanced immunosuppression by therapy-exposed glioblastoma multiforme tumor cells

scientific article published on 12 November 2014

Epigenetic regulation of Th2 cytokine expression in atopic diseases.

scientific article published on 28 June 2008

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein.

scientific article

Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches.

scientific article published on 21 May 2016

How epigenetic imprinting contributes to stabilizing the Th2 phenotype ⬇️

scientific article published on September 25, 2012

Iterative sorting reveals CD133+ and CD133- melanoma cells as phenotypically distinct populations.

scientific article

MSU Crystals Enhance TDB-Mediated Inflammatory Macrophage IL-1β Secretion

scientific article published on 01 June 2019

Mitochondrial Transfer from Astrocytes to Neurons following Ischemic Insult: Guilt by Association?

scientific article published in September 2016

N,N-Bis(glycityl)amines as anti-cancer drugs

scientific article published on 09 April 2016

Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2.

scientific article published on 8 February 2007

Perfluorocarbon emulsions radiosensitise brain tumors in carbogen breathing mice with orthotopic GL261 gliomas

scientific article

Pharmacological concentrations of ascorbate radiosensitize glioblastoma multiforme primary cells by increasing oxidative DNA damage and inhibiting G2/M arrest.

scientific article

Pharmacological doses of daily ascorbate protect tumors from radiation damage after a single dose of radiation in an intracranial mouse glioma model.

scientific article published on 15 December 2014

Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases

scientific article published on 24 September 2015

Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity

scientific article published on 11 June 2009

Radiosensitisation by pharmacological ascorbate in glioblastoma multiforme cells, human glial cells, and HUVECs depends on their antioxidant and DNA repair capabilities and is not cancer specific

scientific article

Side population is not necessary or sufficient for a cancer stem cell phenotype in glioblastoma multiforme

scientific article published in March 2011

Sphere formation reverses the metastatic and cancer stem cell phenotype of the murine mammary tumour 4T1, independently of the putative cancer stem cell marker Sca-1.

scientific article

Targeted inhibition of dominant PI3-kinase catalytic isoforms increase expression of stem cell genes in glioblastoma cancer stem cell models

scientific article published on 9 May 2016

Th2 responses are primed by skin dendritic cells with distinct transcriptional profiles.

scientific article published on 2 December 2016

The Mincle ligand trehalose dibehenate differentially modulates M1-like and M2-like macrophage phenotype and function via Syk signaling.

scientific article published on 19 July 2017

The acute promyelocytic leukemia–associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D3–induced monocytic differentiation of U937 cells through a physical interaction with vitamin D3receptor ⬇️

scientific article (publication date: December 2001)

The co-administration of trehalose dibehenate and monosodium urate crystals promotes an anti-tumour phenotype in human-derived myeloid cells

scientific article published on 17 March 2020

The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific

scientific article (publication date: 19 July 2002)

The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress

scientific article published on July 2011

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy

scientific article published on 22 April 2020

Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F.

scientific article published on 2 July 2010

Vaccination with irradiated tumor cells pulsed with an adjuvant that stimulates NKT cells is an effective treatment for glioma.

scientific article published on 12 November 2012

Paulina is supported by:

About Paulina

Help