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List of works by Nicole M Verrills

A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.

scientific article published on 6 November 2007

A systematic evaluation of the safety and toxicity of fingolimod for its potential use in the treatment of acute myeloid leukaemia.

scientific article

Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.

scientific article published on 25 January 2016

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors.

scientific article published on 18 June 2016

Activity-associated miRNA are packaged in Map1b-enriched exosomes released from depolarized neurons.

scientific article

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia

scientific article published on October 2006

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin

scientific article published on 18 May 2015

Cell-Free DNA Blood Collection Tubes Are Appropriate for Clinical Proteomics: A Demonstration in Colorectal Cancer.

scientific article published on 24 February 2018

Clinical proteomics: present and future prospects.

scientific article

Comment on "PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia"

scientific article published on 01 July 2019

Controlling the cell cycle: the role of calcium/calmodulin-stimulated protein kinases I and II.

scientific article published on 15 February 2011

Dephosphorylation of CaMKII at T253 controls the metaphase-anaphase transition.

scientific article published on 7 January 2014

Development of novel PP2A activators for use in the treatment of acute myeloid leukaemia

scientific article published on 01 May 2016

Drug resistance mechanisms in cancer cells: a proteomics perspective.

scientific article

Essential requirement for PP2A inhibition by the oncogenic receptor c-KIT suggests PP2A reactivation as a strategy to treat c-KIT+ cancers

scientific article

Essential role of protein phosphatase 2A in metaphase II arrest and activation of mouse eggs shown by okadaic acid, dominant negative protein phosphatase 2A, and FTY720.

scientific article

Expression of renin-angiotensin system (RAS) components in endometrial cancer

scientific article published on 12 December 2016

FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia

scientific article

Functional importance of PP2A regulatory subunit loss in breast cancer

scientific article

Harnessing the power of proteomics for identification of oncogenic, druggable signalling pathways in cancer

scientific article published on 13 March 2017

Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease.

scientific article

Improving the targeting of tubulin-binding agents: lessons from drug resistance studies.

scientific article

Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

scientific article

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

scientific article published on 30 August 2017

Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs

scientific article published on 01 September 2004

PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9

scientific article

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

scientific article published on 01 March 2015

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.

scientific article published on 17 March 2014

Peripheral Lipopolysaccharide Challenge Induces Long-Term Changes in Tyrosine Hydroxylase Regulation in the Adrenal Medulla.

scientific article

Protein phosphatase 2A (PP2A): a key phosphatase in the progression of chronic obstructive pulmonary disease (COPD) to lung cancer

scientific article published on 17 October 2019

Protein phosphatase 2A carboxymethylation and regulatory B subunits differentially regulate mast cell degranulation

scientific article published on 2 August 2010

Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations.

scientific article

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.

scientific article published in March 2006

Quantitative phosphoproteomics uncovers synergy between DNA-PK and FLT3 inhibitors in acute myeloid leukaemia

scientific article published on 16 October 2020

Regulation of CaMKII by phospho-Thr253 or phospho-Thr286 sensitive targeting alters cellular function.

scientific article

Salmeterol attenuates chemotactic responses in rhinovirus-induced exacerbation of allergic airways disease by modulating protein phosphatase 2A.

scientific article

Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress ⬇️

scientific article published on June 28, 2012

TLR2 ligation induces corticosteroid insensitivity in A549 lung epithelial cells: Anti-inflammatory impact of PP2A activators.

scientific article published on 28 July 2016

Targeting Oncogenic Signaling in Mutant FLT3 Acute Myeloid Leukemia: The Path to Least Resistance

scientific article published on 16 October 2018

Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice

scientific article

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

scientific article published on 20 January 2013

The microbial proteome database--an automated laboratory catalogue for monitoring protein expression in bacteria

scientific article published on 01 December 1999

The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells

scientific article

The proteomics of ageing

scientific article published on 01 January 2002

Theophylline Represses IL-8 Secretion from Airway Smooth Muscle Cells Independently of Phosphodiesterase Inhibition. Novel Role as a Protein Phosphatase 2A Activator.

scientific article published on 17 November 2015

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

scientific article

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