List of works - Alfonso Buil

A Genome Search for Genetic Determinants That Influence Plasma Fibrinogen Levels

scientific article published on 10 March 2005

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

article by Maria Sabater-Lleal et al published August 2012 in Arteriosclerosis, Thrombosis, and Vascular Biology

A Locus on Chromosome 2 Influences Levels of Tissue Factor Pathway Inhibitor

scientific article published on 21 April 2005

A comparison of discrete versus continuous environment in a variance components-based linkage analysis of the COGA data

scientific article

A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels

scientific article published on 18 September 2014

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

scientific article published on 28 January 2019

A genome-wide association study of the Protein C anticoagulant pathway

scientific article

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels

scientific article published on 18 June 2008

A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project

scientific article

A genomewide study of body mass index and its genetic correlation with thromboembolic risk

scientific article published on 14 August 2014

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

scientific article published on 11 November 2019

A new gene-based association test for genome-wide association studies

scientific article

A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility.

scientific article published on 15 August 2002

A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease

scientific article published on 22 January 2002

A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

scientific article published on 5 January 2007

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

article

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies

scientific article

Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129

scientific article published on 29 March 2019

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

scientific article

Circulating Proteomic Signatures of Chronological Age.

scientific article published on 14 August 2014

Cis and trans effects of human genomic variants on gene expression.

scientific article

Clustering of individuals given SNPs similarity based on normalized mutual information: F7 SNPs in the GAIT sample

scientific article published on 01 January 2007

Correction: Passive and active DNA methylation and the interplay with genetic variation in gene regulation

scientific article published on 14 June 2013

Fast and efficient QTL mapper for thousands of molecular phenotypes.

scientific article published on 26 December 2015

Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women.

scientific article

Gene age predicts the strength of purifying selection acting on gene expression variation in humans

scientific article

Gene expression changes with age in skin, adipose tissue, blood and brain

scientific article

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

scientific article

Genetic and environmental factors influencing the human factor H plasma levels

scientific article

Genetic correlation between plasma levels of C4BP isoforms containing beta chains and susceptibility to thrombosis

scientific article published in January 2004

Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk

article

Genetic determinants of iron metabolism plasma phenotypes and their relationship with risk of thrombosis

scientific article published on 01 December 2003

Genetic determinants of normal variation in coagulation factor (F) IX levels: genome-wide scan and examination of the FIX structural gene

article

Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain

scientific article

Genetic determinants of variation in the plasma levels of the C4b-binding protein (C4BP) in Spanish families

article

Genetic interactions affecting human gene expression identified by variance association mapping

scientific article

Genetic predictors of educational attainment and intelligence test performance predict voter turnout

scientific article published on 09 November 2020

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

scientific article published on 11 January 2016

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

scientific article

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth

scientific article published on 23 November 2020

Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels

scientific article published on 18 June 2008

Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project

scientific article published on 01 March 2003

Genomewide linkage analysis of soluble transferrin receptor plasma levels

scientific article published on 23 August 2005

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements.

scientific article published in December 2013

Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements

scientific article published on 31 October 2013

Heritability of plasma concentrations of activated protein C in a Spanish population

article

Heritability of thromboxane A2 and prostaglandin E2 biosynthetic machinery in a Spanish population

scientific article

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study

scientific article published on 12 June 2009

Identification of a novel quantitative trait nucleotype related to iron status in a calcium channel gene.

scientific article published on January 2013

Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins?

scientific article

Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS.

scientific article

MISS: a non-linear methodology based on mutual information for genetic association studies in both population and sib-pairs analysis

scientific article published on 18 June 2010

Mapping cis- and trans-regulatory effects across multiple tissues in twins

scientific article published on 02 September 2012

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

scientific article published on 4 June 2013

Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

scientific article

Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project

scientific article

Quantitative variability of 342 plasma proteins in a human twin population

scientific article

SNP sets selection under mutual information criterion, application to F7/FVII dataset.

scientific article published in January 2008

Searching for master regulators of transcription in a human gene expression data set.

scientific article

Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels

scientific article

Sex-biased genetic effects on gene regulation in humans

scientific article

Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci

scientific article

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

scientific article

Smoothing of the bivariate LOD score for non-normal quantitative traits

scientific article

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

scientific article published in Nature Communications

Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data

scientific article published on January 2007

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

scientific article (publication date: 4 January 2016)

Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing

scientific article published on 29 January 2015

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

solarius: an R interface to SOLAR for variance component analysis in pedigrees

scientific article published on 15 February 2016

List of works by Alfonso Buil

A Genome Search for Genetic Determinants That Influence Plasma Fibrinogen Levels

A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time

A Locus on Chromosome 2 Influences Levels of Tissue Factor Pathway Inhibitor

A comparison of discrete versus continuous environment in a variance components-based linkage analysis of the COGA data

A genome-wide association study in the genetic analysis of idiopathic thrombophilia project suggests sex-specific regulation of mitochondrial DNA levels

A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment

A genome-wide association study of the Protein C anticoagulant pathway

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels

A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project

A genomewide study of body mass index and its genetic correlation with thromboembolic risk

A large-scale genomic investigation of susceptibility to infection and its association with mental disorders in the Danish population

A new gene-based association test for genome-wide association studies

A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility.

A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease

A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort

C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies

Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129

Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation

Circulating Proteomic Signatures of Chronological Age.

Cis and trans effects of human genomic variants on gene expression.

Clustering of individuals given SNPs similarity based on normalized mutual information: F7 SNPs in the GAIT sample

Correction: Passive and active DNA methylation and the interplay with genetic variation in gene regulation

Fast and efficient QTL mapper for thousands of molecular phenotypes.

Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women.

Gene age predicts the strength of purifying selection acting on gene expression variation in humans

Gene expression changes with age in skin, adipose tissue, blood and brain

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins

Genetic and environmental factors influencing the human factor H plasma levels

Genetic correlation between plasma levels of C4BP isoforms containing beta chains and susceptibility to thrombosis

Genetic determinants of 5-lipoxygenase pathway in a Spanish population and their relationship with cardiovascular risk

Genetic determinants of iron metabolism plasma phenotypes and their relationship with risk of thrombosis

Genetic determinants of normal variation in coagulation factor (F) IX levels: genome-wide scan and examination of the FIX structural gene

Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain

Genetic determinants of variation in the plasma levels of the C4b-binding protein (C4BP) in Spanish families

Genetic interactions affecting human gene expression identified by variance association mapping

Genetic predictors of educational attainment and intelligence test performance predict voter turnout

Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth

Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels

Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT project

Genomewide linkage analysis of soluble transferrin receptor plasma levels

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements.

Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements

Heritability of plasma concentrations of activated protein C in a Spanish population

Heritability of thromboxane A2 and prostaglandin E2 biosynthetic machinery in a Spanish population

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study

Identification of a novel quantitative trait nucleotype related to iron status in a calcium channel gene.

Identification of antithrombin-modulating genes. Role of LARGE, a gene encoding a bifunctional glycosyltransferase, in the secretion of proteins?

Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS.

MISS: a non-linear methodology based on mutual information for genetic association studies in both population and sib-pairs analysis

Mapping cis- and trans-regulatory effects across multiple tissues in twins

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project

Quantitative variability of 342 plasma proteins in a human twin population

SNP sets selection under mutual information criterion, application to F7/FVII dataset.

Searching for master regulators of transcription in a human gene expression data set.

Sequence variation and genetic evolution at the human F12 locus: mapping quantitative trait nucleotides that influence FXII plasma levels

Sex-biased genetic effects on gene regulation in humans

Sex-specific regulation of mitochondrial DNA levels: genome-wide linkage analysis to identify quantitative trait loci

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

Smoothing of the bivariate LOD score for non-normal quantitative traits

Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia

Summary of Genetic Analysis Workshop 15: Group 9 linkage analysis of the CEPH expression data

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases

Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

solarius: an R interface to SOLAR for variance component analysis in pedigrees