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List of works by Frédéric Coin

A chromatin scaffold for DNA damage recognition: how histone methyltransferases prime nucleosomes for repair of ultraviolet light-induced lesions

scientific article published on 01 February 2020

A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor.

scientific article published on 17 May 2011

A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

scientific article

A small molecule screen identifies an inhibitor of DNA repair inducing the degradation of TFIIH and the chemosensitization of tumor cells to platinum.

scientific article published on 6 February 2014

Activation of P-TEFb by RBM7: To Live or Let Die

scientific article published on 01 April 2019

Affinity Purification of Human DNA Repair/Transcription Factor TFIIH Using Epitope-tagged Xeroderma Pigmentosum B Protein ⬇️

scientific article published on January 9, 1998

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

scientific article published in December 1997

Cockayne's Syndrome A and B Proteins Regulate Transcription Arrest after Genotoxic Stress by Promoting ATF3 Degradation

scientific article published on 30 November 2017

Conducting the CTD orchestra

scientific article published on 01 February 2019

DNA Damage Recognition by XPA Protein Promotes Efficient Recruitment of Transcription Factor II H ⬇️

scientific article published on September 12, 1997

DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility.

scientific article published on 5 March 2007

DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription

scientific article published on 16 September 2019

Defective transcription of ATF3 responsive genes, a marker for Cockayne Syndrome

scientific article published on 24 January 2020

Dissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC.

scientific article published on 22 September 2008

Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair

scientific article

Distinct roles for the helicases of TFIIH in transcript initiation and promoter escape

scientific article published on 01 January 2000

ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair

scientific article published on 14 October 2013

Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression

article

Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack.

scientific article

Lurbinectedin Specifically Triggers the Degradation of Phosphorylated RNA Polymerase II and the Formation of DNA Breaks in Cancer Cells.

scientific article published on 14 September 2016

Molecular insights into the recruitment of TFIIH to sites of DNA damage

scientific article published on 27 August 2009

Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

scientific article

Nucleotide excision repair driven by the dissociation of CAK from TFIIH.

scientific article

Orchestral maneuvers at the damaged sites in nucleotide excision repair

scientific article published on 15 February 2015

Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors

scientific article published on 23 February 2004

Phosphorylation of XPD drives its mitotic role independently of its DNA repair and transcription functions

scientific article published in 2022

Poly (ADP-ribose) glycohydrolase regulates retinoic acid receptor-mediated gene expression

scientific article published on 25 October 2012

Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells

scientific article published on 09 March 2022

Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

scientific journal article

Regulatory interplay of Cockayne syndrome B ATPase and stress-response gene ATF3 following genotoxic stress

scientific article published on 03 June 2013

Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles

scientific article

Revisiting the Function of CDK7 in Transcription by Virtue of a Recently Described TFIIH Kinase Inhibitor.

scientific article

Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin

scientific article

Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy

scientific article

TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription

article

TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.

scientific article

The long unwinding road: XPB and XPD helicases in damaged DNA opening.

scientific article published on 05 January 2010

Transcription activities at 8-oxoG lesions in DNA.

scientific article published in November 2004

Transcription without XPB Establishes a Unified Helicase-Independent Mechanism of Promoter Opening in Eukaryotic Gene Expression.

scientific article published in February 2017

Transcriptional activators stimulate DNA repair.

scientific article

True lies: the double life of the nucleotide excision repair factors in transcription and DNA repair

scientific article

Two sides of the same coin: TFIIH complexes in transcription and DNA repair.

scientific article published on 13 April 2010

Unified promoter opening steps in eukaryotic gene expression.

scientific article published on 29 September 2017

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.

scientific article

p52 Mediates XPB function within the transcription/repair factor TFIIH.

scientific article published on 21 June 2002

p8/TTD-A as a repair-specific TFIIH subunit

scientific article published in January 2006

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