List of works - Matthew Auton

"Cooperative collapse" of the denatured state revealed through Clausius-Clapeyron analysis of protein denaturation phase diagrams.

scientific article published on 19 February 2018

A molten globule intermediate of the von Willebrand factor A1 domain firmly tethers platelets under shear flow

scientific article

Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins

scientific article

Anatomy of energetic changes accompanying urea-induced protein denaturation.

scholarly article

Application of the transfer model to understand how naturally occurring osmolytes affect protein stability

scientific article published on 01 January 2007

Arabinose Alters Both Local and Distal H-D Exchange Rates in the Escherichia coli AraC Transcriptional Regulator

scientific article published on 19 June 2019

Attack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.

scientific article

Chaperonin-Based Biolayer Interferometry To Assess the Kinetic Stability of Metastable, Aggregation-Prone Proteins

scientific article published on 9 August 2016

Conformational stability and domain unfolding of the Von Willebrand factor A domains

scientific article published on 25 October 2006

Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain.

scientific article

Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.

scientific article published on 14 June 2013

Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics

scientific article published on 03 September 2019

Kinetic Control in Protein Folding for Light Chain Amyloidosis and the Differential Effects of Somatic Mutations

scientific article

Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal

scientific article published on 04 August 2006

Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease

scientific article

Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor.

scientific article

N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress.

scientific article published on 19 March 2012

Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains.

scientific article published on 19 May 2011

Oxidative refolding of rPA in l-ArgHCl and in ionic liquids: A correlation between hydrophobicity, salt effects, and refolding yield

scientific article

Platelet-type von Willebrand disease: Local disorder of the platelet GPIbα β-switch drives high-affinity binding to von Willebrand factor

scientific article published on 19 September 2019

Predicting the energetics of osmolyte-induced protein folding/unfolding.

scientific article

Protein stability in the presence of cosolutes

scientific article published on 01 January 2011

Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.

scientific article

The Von Willebrand Factor A1-Collagen III Interaction Is Independent of Conformation and Type 2 Von Willebrand Disease Phenotype

scientific article published on 23 November 2016

The effects of N-ethyl-N'-methyl imidazolium chloride on the solubility, stability and aggregation of tc-rPA.

scientific article

The linker between the D3 and A1 domains of vWF suppresses A1-GPIbα catch bonds by site-specific binding to the A1 domain.

scientific article

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

scientific article published on 26 October 2018

Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding

scientific article

Untangling a Structurally Resolved Protein Folding Intermediate

scientific article

Urea-temperature phase diagrams capture the thermodynamics of denatured state expansion that accompany protein unfolding.

scientific article published on 25 July 2013

List of works by Matthew Auton

"Cooperative collapse" of the denatured state revealed through Clausius-Clapeyron analysis of protein denaturation phase diagrams.

A molten globule intermediate of the von Willebrand factor A1 domain firmly tethers platelets under shear flow

Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins

Anatomy of energetic changes accompanying urea-induced protein denaturation.

Application of the transfer model to understand how naturally occurring osmolytes affect protein stability

Arabinose Alters Both Local and Distal H-D Exchange Rates in the Escherichia coli AraC Transcriptional Regulator

Attack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.

Chaperonin-Based Biolayer Interferometry To Assess the Kinetic Stability of Metastable, Aggregation-Prone Proteins

Conformational stability and domain unfolding of the Von Willebrand factor A domains

Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p.Gly1324Ser) of the von Willebrand factor A1 domain.

Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.

Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics

Kinetic Control in Protein Folding for Light Chain Amyloidosis and the Differential Effects of Somatic Mutations

Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal

Misfolding of vWF to pathologically disordered conformations impacts the severity of von Willebrand disease

Mutational Constraints on Local Unfolding Inhibit the Rheological Adaptation of von Willebrand Factor.

N-terminal flanking region of A1 domain in von Willebrand factor stabilizes structure of A1A2A3 complex and modulates platelet activation under shear stress.

Osmolyte effects on protein stability and solubility: a balancing act between backbone and side-chains.

Oxidative refolding of rPA in l-ArgHCl and in ionic liquids: A correlation between hydrophobicity, salt effects, and refolding yield

Platelet-type von Willebrand disease: Local disorder of the platelet GPIbα β-switch drives high-affinity binding to von Willebrand factor

Predicting the energetics of osmolyte-induced protein folding/unfolding.

Protein stability in the presence of cosolutes

Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.

The Von Willebrand Factor A1-Collagen III Interaction Is Independent of Conformation and Type 2 Von Willebrand Disease Phenotype

The effects of N-ethyl-N'-methyl imidazolium chloride on the solubility, stability and aggregation of tc-rPA.

The linker between the D3 and A1 domains of vWF suppresses A1-GPIbα catch bonds by site-specific binding to the A1 domain.

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding

Untangling a Structurally Resolved Protein Folding Intermediate

Urea-temperature phase diagrams capture the thermodynamics of denatured state expansion that accompany protein unfolding.