List of works - Koji Furukawa

A role of the third complementarity-determining region in the affinity maturation of an antibody.

scientific article published on 25 May 2001

A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy

scientific article

An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruzi

scientific article published on 29 February 2016

An optimized procedure for efficient phage display of antibody fragments with a low folding efficiency

scientific article

Augmented antibody response with premature germinal center regression in CD40L transgenic mice.

scientific article published on 26 May 2010

BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.

scientific article published on 5 July 2004

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus

scientific article published on 10 September 2013

CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.

scientific article published on 24 October 2016

Conformational analysis of human serum albumin and its non-enzymatic glycation products using monoclonal antibodies

scientific article published on 21 January 2011

Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificity

scientific article published on 01 August 1999

Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma brucei.

scientific article

Development of a motion-based cell-counting system for Trypanosoma parasite using a pattern recognition approach

article

Efficient bacterial production of functional antibody fragments using a phagemid vector

scientific article

Fibrinogen Nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer

scientific article published on 01 January 1989

Identification of indispensable residues for specific DNA-binding in the imperfect tandem repeats of c-Myb R2R3 ⬇️

scientific article published on December 1, 1997

Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturation

scientific article published on 9 January 2006

Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle

scientific article published on 14 October 2016

Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

scientific article published on 31 July 2019

Junctional amino acids determine the maturation pathway of an antibody.

scientific article published in September 1999

Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance

scientific article published on 01 July 1999

NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes

scientific article published on 04 June 2018

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

scientific article published on 11 July 2013

Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl hapten

scientific article published on 21 November 2006

T cells specific to hapten carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodies.

scientific article

Thermodynamic and kinetic aspects of antibody evolution during the immune response to hapten.

scientific article

Thermodynamics of specific and non-specific DNA binding by the c-myb DNA-binding domain ⬇️

scientific article published on February 27, 1998

Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi

article

List of works by Koji Furukawa

A role of the third complementarity-determining region in the affinity maturation of an antibody.

A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropy

An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruzi

An optimized procedure for efficient phage display of antibody fragments with a low folding efficiency

Augmented antibody response with premature germinal center regression in CD40L transgenic mice.

BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response.

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus

CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP.

Conformational analysis of human serum albumin and its non-enzymatic glycation products using monoclonal antibodies

Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificity

Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma brucei.

Development of a motion-based cell-counting system for Trypanosoma parasite using a pattern recognition approach

Efficient bacterial production of functional antibody fragments using a phagemid vector

Fibrinogen Nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer

Identification of indispensable residues for specific DNA-binding in the imperfect tandem repeats of c-Myb R2R3 ⬇️

Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturation

Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycle

Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System

Junctional amino acids determine the maturation pathway of an antibody.

Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonance

NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes

Repression of the transcription factor Bach2 contributes to predisposition of IgG1 memory B cells toward plasma cell differentiation.

Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl hapten

T cells specific to hapten carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodies.

Thermodynamic and kinetic aspects of antibody evolution during the immune response to hapten.

Thermodynamics of specific and non-specific DNA binding by the c-myb DNA-binding domain ⬇️

Utilization of proliferable extracellular amastigotes for transient gene expression, drug sensitivity assay, and CRISPR/Cas9-mediated gene knockout in Trypanosoma cruzi