List of works - Emiliano Biasini

A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.

scientific article

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.

scientific article published on 15 March 2016

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity

scientific article published on February 2013

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

scientific article

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo.

scientific article

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

scientific article published on December 2008

An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo

scientific article published on 28 January 2013

An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity

scientific article

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.

scientific article published on 07 August 2017

Common therapeutic strategies for prion and Alzheimer's diseases.

scientific article

Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases

scientific article published on 23 October 2014

Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases.

scientific article

Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury

scientific article

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

scholarly article

Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface

scientific article published on 18 July 2019

Immunopurification of pathological prion protein aggregates

scientific article

Ion channels induced by the prion protein: mediators of neurotoxicity.

scientific article published in January 2012

Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion

scientific article published on 21 November 2007

Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway

scientific article

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

scientific article

Pharmacological inactivation of the prion protein by targeting a folding intermediate

scientific article published on 12 January 2021

Prion protein at the crossroads of physiology and disease.

scientific article published on December 2011

Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells.

scientific article

Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.

scientific article

Redox regulation of cyclophilin A by glutathionylation.

scientific article published in February 2006

Role of lipid rafts and GM1 in the segregation and processing of prion protein

scientific article

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

scientific article

Targeting the cellular prion protein to treat neurodegeneration.

scientific article published in September 2012

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

scientific article published on 06 July 2016

The N-terminal, polybasic region is critical for prion protein neuroprotective activity

scientific article

The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).

scientific article

The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells.

scientific article

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells

scientific article

List of works by Emiliano Biasini

A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity.

A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein.

A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity

A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.

Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo.

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo

An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity

An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein.

Common therapeutic strategies for prion and Alzheimer's diseases.

Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases

Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases.

Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface

Immunopurification of pathological prion protein aggregates

Ion channels induced by the prion protein: mediators of neurotoxicity.

Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion

Mutant prion protein expression is associated with an alteration of the Rab GDP dissociation inhibitor alpha (GDI)/Rab11 pathway

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

Pharmacological inactivation of the prion protein by targeting a folding intermediate

Prion protein at the crossroads of physiology and disease.

Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells.

Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse.

Redox regulation of cyclophilin A by glutathionylation.

Role of lipid rafts and GM1 in the segregation and processing of prion protein

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

Targeting the cellular prion protein to treat neurodegeneration.

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

The N-terminal, polybasic region is critical for prion protein neuroprotective activity

The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).

The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells.

The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells