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List of works by Teresita M. Bellido

A Correlation between Wnt/Beta-catenin Signaling and the Rate of Dentin Secretion

scientific article published on 12 September 2019

A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

scientific article published on 03 July 2007

A scaffold-free multicellular three-dimensional in vitro model of osteogenesis.

scientific article published on 12 February 2011

Aberrantly elevated Wnt signaling is responsible for cementum overgrowth and dental ankylosis

scientific article published on 25 October 2018

Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice ⬇️

scientific article published on March 11, 2013

Anabolic and catabolic regimens of human parathyroid hormone 1-34 elicit bone- and envelope-specific attenuation of skeletal effects in Sost-deficient mice

scientific article

Antagonistic interplay between mechanical forces and glucocorticoids in bone: a tale of kinases

scientific article published on September 2010

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts

Author Correction: Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling

scientific article published on 01 May 2019

Avenanthramides Prevent Osteoblast and Osteocyte Apoptosis and Induce Osteoclast Apoptosis in Vitro in an Nrf2-Independent Manner

scientific article published on 11 July 2016

Beyond gap junctions: Connexin43 and bone cell signaling ⬇️

scientific article published on October 2, 2012

Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma

scientific article published on February 2016

Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.

scientific article published on 17 January 2012

Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation.

scientific article

CD40 Ligand Blocks Apoptosis Induced by Tumor Necrosis Factor α, Glucocorticoids, and Etoposide in Osteoblasts and the Osteocyte-Like Cell Line Murine Long Bone Osteocyte-Y4 ⬇️

scientific article published on May 1, 2003

Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.

scientific article published on February 2012

Comment on Osteocytes: masters orchestrators of bone

scientific article published on 13 August 2014

Conditional Deletion of Murine Fgf23: Interruption of the Normal Skeletal Responses to Phosphate Challenge and Rescue of Genetic Hypophosphatemia

scientific article published on 21 January 2016

Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo

scientific article

Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone

scientific article

Consumption of Rabbiteye Blueberry Results in Accumulation of Hippuric Acid in the Bone Marrow and Increased Bone Deposition in Ovariectomized Rats but Few Other Bone Benefits (P06-064-19)

Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor

scientific article

Control of bone mass and remodeling by PTH receptor signaling in osteocytes

scientific article

Crosstalk between Caveolin-1/Extracellular Signal-regulated Kinase (ERK) and β-Catenin Survival Pathways in Osteocyte Mechanotransduction ⬇️

scientific article published on January 28, 2013

Cx43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice.

scientific article published on 18 January 2018

Defective cancellous bone structure and abnormal response to PTH in cortical bone of mice lacking Cx43 cytoplasmic C-terminus domain.

scientific article

Detection of apoptosis of bone cells in vitro

scientific article published on 01 January 2008

Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth

scientific article published on 6 June 2017

Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging

scientific article

Dissociation of the pro-apoptotic effects of bisphosphonates on osteoclasts from their anti-apoptotic effects on osteoblasts/osteocytes with novel analogs

scientific article published on 19 April 2006

Effects of PTH on osteocyte function ⬇️

scientific article published on September 24, 2012

Erratum: Osteocytic signalling pathways as therapeutic targets for bone fragility

correction of a scholarly article

Ex Vivo Organ Cultures as Models to Study Bone Biology

scientific article published on 14 February 2020

Forum on aging and skeletal health: summary of the proceedings of an ASBMR workshop

scientific article published on 13 September 2011

GLUCOCORTICOID EXCESS IN BONE AND MUSCLE

scientific article published on 05 February 2018

Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2/Anoikis Signaling

scientific article published on 01 July 2019

Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

scientific article published in March 2017

Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength

scientific article published on 22 December 2003

Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis

scientific article

High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo

scientific article published on 24 March 2015

IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production

scientific article published on 06 November 2018

Induction of osteoblast differentiation by selective activation of kinase-mediated actions of the estrogen receptor

scientific article published on 11 December 2006

Inhibition of osteocyte apoptosis prevents the increase in osteocytic receptor activator of nuclear factor κB ligand (RANKL) but does not stop bone resorption or the loss of bone induced by unloading

scientific article published on 17 June 2015

Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids

scientific article

Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma

scientific article published in October 2004

Klotho expression in osteocytes regulates bone metabolism and controls bone formation

scientific article published on 8 April 2017

Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo

scientific article published on 18 September 2019

MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production

scientific article published on 17 January 2018

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

scientific article

Mechanobiology of the skeleton.

scientific article

New Insights Into the Local and Systemic Functions of Sclerostin: Regulation of Quiescent Bone Lining Cells and Beige Adipogenesis in Peripheral Fat Depots

scientific article published on 29 March 2017

Nongenotropic, anti-apoptotic signaling of 1alpha,25(OH)2-vitamin D3 and analogs through the ligand binding domain of the vitamin D receptor in osteoblasts and osteocytes. Mediation by Src, phosphatidylinositol 3-, and JNK kinases

scientific article

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner

scientific article

Novel actions of bisphosphonates in bone: Preservation of osteoblast and osteocyte viability ⬇️

scientific article published on August 18, 2010

Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age.

scientific article

Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells

scientific article published on 18 January 2012

Osteocyte apoptosis induces bone resorption and impairs the skeletal response to weightlessness

article

Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss

scientific article

Osteocyte-driven bone remodeling

scientific article published on 04 September 2013

Osteocytes and Skeletal Pathophysiology

scientific article

Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone

scientific article

Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover

scientific article published on 08 October 2019

Osteocytic signalling pathways as therapeutic targets for bone fragility

scientific article published on 27 May 2016

Overexpression of WNT16 Does Not Prevent Cortical Bone Loss Due to Glucocorticoid Treatment in Mice

scientific article published on 23 October 2018

PTH receptor signaling in osteocytes governs periosteal bone formation and intracortical remodeling.

scientific article

PTHrP-Derived Peptides Restore Bone Mass and Strength in Diabetic Mice: Additive Effect of Mechanical Loading

scientific article published on 28 September 2016

Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo ⬇️

scientific article published on June 25, 2011

Parathyroid hormone receptor signaling induces bone resorption in the adult skeleton by directly regulating the RANKL gene in osteocytes

scientific article

Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice

scientific article

Prevention of glucocorticoid-induced apoptosis in osteocytes and osteoblasts by calbindin-D28k

scientific article published on 22 December 2003

Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

scientific article

Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism

scientific article published in October 2003

Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

scientific article published on 10 May 2016

Resorption Controls Bone Anabolism Driven by Parathyroid Hormone (PTH) Receptor Signaling in Osteocytes ⬇️

scientific article published on August 20, 2013

Response to Windahl et al.

scientific article published in November 2006

Reversal of loss of bone mass in old mice treated with mefloquine

Role and mechanism of action of sclerostin in bone

scientific article published on 11 October 2016

Role of TGF-β in a mouse model of high turnover renal osteodystrophy

scientific article

Role of osteocytes in multiple myeloma bone disease

scientific article

Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Model

scientific article published on 8 June 2015

Skeletal cell YAP and TAZ combinatorially promote bone development

scientific article published on 10 January 2018

Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids

scientific article

Skeletal protection and promotion of microbiome diversity by dietary boosting of the endogenous antioxidant response

scientific article published on 14 December 2020

Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

scientific article published on 30 October 2011

Stat3 in osteocytes mediates osteogenic response to loading

scientific article published on 29 July 2019

TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone

scientific article published on 22 March 2019

Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop

scientific article published on 01 March 2009

The Sirtuin1 activator SRT3025 down-regulates sclerostin and rescues ovariectomy-induced bone loss and biomechanical deterioration in female mice

scientific article

Transduction of Cell Survival Signals by Connexin-43 Hemichannels ⬇️

scientific article published on December 10, 2001

Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling

scientific article published on 07 January 2019

Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens

scientific article published on 22 November 2004

Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

scientific article

YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling

scientific article published on 14 October 2019

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