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List of works by Martin Horn

A Coumarin-Labeled Vinyl Sulfone as Tripeptidomimetic Activity-Based Probe for Cysteine Cathepsins

scientific article published on 19 March 2014

Activation processing of cathepsin H impairs recognition by its propeptide.

scientific article published in September 2005

Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to <i>Schistosoma mansoni</i>: Structural and Mechanistic Insights into Chemotype Reactivity

scientific article published on 10 December 2020

Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis

scientific article published on 13 February 2020

Cathepsin D Propeptide: Mechanism and Regulation of Its Interaction with the Catalytic Core†

scientific article published on 01 December 2006

Characterization of gut-associated cathepsin D hemoglobinase from tick Ixodes ricinus (IrCD1).

scientific article

Complex modulation of peptidolytic activity of cathepsin D by sphingolipids

scientific article published on 23 September 2011

Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata

scientific article

De novo design of alpha-amylase inhibitor: a small linear mimetic of macromolecular proteinaceous ligands

scientific article published in December 2005

Differential elicitation of two processing proteases controls the processing pattern of the trypsin proteinase inhibitor precursor in Nicotiana attenuata

scientific article

Digestive proteolysis in the Colorado potato beetle, Leptinotarsa decemlineata: Activity-based profiling and imaging of a multipeptidase network

scientific article published on 15 August 2016

Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors

scientific article published on 11 November 2020

Excretion/secretion products from Schistosoma mansoni adults, eggs and schistosomula have unique peptidase specificity profiles.

scientific article published on 24 September 2015

Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics

scientific article (publication date: 30 October 2009)

Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes

scientific article published on 01 December 2022

Inhibitory specificity and insecticidal selectivity of alpha-amylase inhibitor from Phaseolus vulgaris.

scientific article published in January 2005

IrCL1 - the haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus.

scientific article

Mapping the pro-peptide of the Schistosoma mansoni cathepsin B1 drug target: modulation of inhibition by heparin and design of mimetic inhibitors.

scientific article

Multienzyme degradation of host serum albumin in ticks

scientific article published on 19 December 2015

Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis

scientific article published in 2024

New insights into the machinery of blood digestion by ticks ⬇️

scientific article published on 07 May 2013

Ontogeny constrains systemic protease inhibitor response in Nicotiana attenuata

scientific article published on March 2001

Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors

scientific article

Quantum Mechanics-Based Scoring Rationalizes the Irreversible Inactivation of Parasitic Schistosoma mansoni Cysteine Peptidase by Vinyl Sulfone Inhibitors

scientific article published on 21 November 2013

RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening

scientific article

Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome

scientific article published on 01 July 2010

SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties

scientific article published on 20 April 2018

Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization

scientific article published on 22 May 2021

Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni

scientific article

Trypsin- and Chymotrypsin-like serine proteases in schistosoma mansoni-- 'the undiscovered country'.

scientific article

Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity.

scientific article

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