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List of works by Neil Brockdorff

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

scientific article

A candidate spermatogenesis gene on the mouse Y chromosome is homologous to ubiquitin-activating enzyme E1 ⬇️

scientific article published on December 12, 1991

A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements

scientific article

A scaffold for X chromosome inactivation.

scientific article published on 10 June 2011

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

scientific article published in Nature Communications

Advances in understanding chromosome silencing by the long non-coding RNA Xist

scientific article

Centrosomal association of histone macroH2A1.2 in embryonic stem cells and somatic cells

scientific article published on 01 August 2001

Characterisation of molecular DNA rearrangements within the Xq12-q13.1 region, in three patients with X-linked hypohidrotic ectodermal dysplasia (EDA).

scientific article published on October 1993

Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution

scientific article

Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence

scientific article (publication date: May 2001)

Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins

scientific article

Chromosome silencing mechanisms in X-chromosome inactivation: unknown unknowns.

scientific article published on December 2011

Cloning of Tabby, the murine homolog of the human EDA gene: evidence for a membrane-associated protein with a short collagenous domain.

scientific article published on September 1997

Comparative mapping of X chromosomes in vole species of the genus Microtus

scientific article published on 01 January 1998

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

scientific article

Considerations when investigating lncRNA function in vivo.

scientific article

Construction of a detailed molecular map of the mouse X chromosome by microcloning and interspecific crosses.

scientific article

Control of Chromosomal Localization of Xist by hnRNP U Family Molecules

scientific article published in October 2016

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7

scientific article

Developmentally regulated Xist promoter switch mediates initiation of X inactivation.

scientific article published on September 1998

Difference between random and imprinted X inactivation in common voles.

scientific article published on 15 May 2010

Differential patterns of histone methylation and acetylation distinguish active and repressed alleles at X-linked genes.

scientific article published in January 2002

Dosage compensation in mammals.

scientific article

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells.

scientific article

Enox, a novel gene that maps 10 kb upstream of Xist and partially escapes X inactivation

scientific article published on 01 August 2002

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes

scientific journal article

Evidence that random and imprinted Xist expression is controlled by preemptive methylation.

scientific article published on April 1994

FGF4 independent derivation of trophoblast stem cells from the common vole

scientific article

Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.

scientific article published on 17 June 2016

Functional analysis of the highly conserved exon IV of XIST RNA

scientific article published on 01 January 2002

Genes flanking Xist in mouse and human are separated on the X chromosome in American marsupials

scientific article

Genetic mapping in the region of the mouse X-inactivation center

scientific article published on 01 August 1990

Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome features.

scientific article

Genome-wide shRNA screening to identify factors mediating Gata6 repression in mouse embryonic stem cells.

scientific article

Global hypomethylation of the genome in XX embryonic stem cells.

scientific article published on 23 October 2005

Heterochromatin on the inactive X chromosome delays replication timing without affecting origin usage

scientific article

High-density molecular map of the central span of the mouse X chromosome

scientific article published on 01 May 1991

High-resolution analysis of epigenetic changes associated with X inactivation.

scientific article published on 06 July 2009

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

scientific article published on 10 December 2001

Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.

scientific article published on February 2002

Histone macroH2A1.2 relocates to the inactive X chromosome after initiation and propagation of X-inactivation.

scientific article

Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome.

scientific article

Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development

scientific article published on 16 July 2015

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

scientific article

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

scientific article published on 16 May 2010

KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands.

scientific article

Local Tandem Repeat Expansion in RNA as a Model for the Functionalisation of ncRNA

Localization of the human X-linked gene for chronic granulomatous disease to the mouse X chromosome: implications for X-chromosome evolution

scientific article published on 01 January 1988

Mammalian polycomb-like Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate polycomb activity both at the Hox gene cluster and at Cdkn2a genes

scientific journal article

MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells.

scientific article published on 13 April 2016

Molecular and genetic mapping of the mouse mdx locus.

scientific article

Noncoding RNA and Polycomb recruitment.

scientific article published on 19 February 2013

Oestrogen-induced changes in the relative concentrations of ribonuclease and ribonuclease inhibitor in rat uterus

scientific article published on 01 February 1986

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

scientific article published on 10 August 2016

PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation

scientific article published on June 2017

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus

scientific article published on 01 March 1993

Polycomb complexes in X chromosome inactivation.

scientific article published on November 2017

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation

scientific journal article

Preface

scientific article published on 01 November 2017

Purification and characterisation of ribonuclease activities that interact with the cytoplasmic inhibitor protein of rat tissues

scientific article published on 01 February 1987

RNA binding proteins implicated in Xist-mediated chromosome silencing.

scientific article published on 24 January 2016

RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3.

scientific article

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

scientific article

Repetitive DNA sequences in the common vole: cloning, characterization and chromosome localization of two novel complex repeats MS3 and MS4 from the genome of the East European vole Microtus rossiaemeridionalis.

scientific article published in August 1998

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells

article

SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks

scientific article

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination

scientific article published on 25 February 2019

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

scientific journal article

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

scientific article published on 01 November 2018

Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome.

scientific article

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy

scientific article

Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.

scientific article

Structure and expression pattern of Oct4 gene are conserved in vole Microtus rossiaemeridionalis

scientific article

Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation

scientific article published on 16 July 2019

Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

scientific article

The interplay of histone modifications - writers that read

scientific article

The long-range mapping of mammalian chromosomes

scientific article published on 01 January 1988

The matrix protein hnRNP U is required for chromosomal localization of Xist RNA.

scientific article published on September 2010

The mouse Smcx gene exhibits developmental and tissue specific variation in degree of escape from X inactivation.

scientific article published in September 1996

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

scientific article published in Nature Communications

The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory

scientific article

The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus

scientific article (publication date: 30 October 1992)

The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation

scientific article published on 17 February 2020

Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

scientific article

Transcription initiation activity sets replication origin efficiency in mammalian cells

scientific article (publication date: April 2009)

Unbiased Genetic Screen to Identify Factors Involved in X-Chromosome Inactivation Using a Pooled Bar-Coded shRNA Library

scientific article published on 01 January 2018

Unusual molecular characteristics of a repeat sequence island within a Giemsa-positive band on the mouse X chromosome

scientific article

Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation

scientific article (publication date: 2011)

Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation.

scientific article published on 22 May 2014

Xist RNA exhibits a banded localization on the inactive X chromosome and is excluded from autosomal material in cis

scientific article published on 01 February 1999

Xist expression and macroH2A1.2 localisation in mouse primordial and pluripotent embryonic germ cells

scientific article

hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing.

scientific article published in December 2017

m6A modification of non-coding RNA and the control of mammalian gene expression

scientific article published on 11 December 2018

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