List of works - Catherine Louise Worth

A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.

scientific article published in December 2007

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity

scientific article

An interactive web-tool for molecular analyses links naturally occurring mutation data with three-dimensional structures of the rhodopsin-like glycoprotein hormone receptors

scientific article

Binding sites in membrane proteins--diversity, druggability and prospects

scientific article published on 27 August 2011

Cells and gene expression programs in the adult human heart

scientific article published on 05 April 2020

Cells of the adult human heart

scientific article published on 24 September 2020

Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models

scientific article

Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm

scientific article

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

scientific article published on 30 December 2017

Family 18 chitinase–oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A

scientific article

FragmentStore--a comprehensive database of fragments linking metabolites, toxic molecules and drugs

scientific article

From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).

scientific article published on 17 May 2011

GPCR-SSFE 2.0-a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.

scientific article published on 05 June 2017

GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models

scientific article

Genome bioinformatic analysis of nonsynonymous SNPs

scientific article

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

scientific article

Meet me halfway: when genomics meets structural bioinformatics

scientific article

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

scientific article published on 10 February 2017

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture

scientific article

PDBLIG: classification of small molecular protein binding in the Protein Data Bank

scientific article

Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.

scientific article

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

scientific article published on 16 November 2021

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

scientific article

Research resource: Update and extension of a glycoprotein hormone receptors web application

scientific article published on 3 February 2011

Residues of a proposed gate region in type I ATP-binding cassette import systems are crucial for function as revealed by mutational analysis

scientific article published on 6 June 2013

SDM--a server for predicting effects of mutations on protein stability and malfunction ⬇️

scientific article

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains.

scientific article

Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor

scientific article published on 23 February 2010

Structural and functional constraints in the evolution of protein families

scientific article published on 16 September 2009

Structural and functional restraints in the evolution of protein families and superfamilies.

scientific article published on August 2009

Structural bioinformatics mutation analysis reveals genotype-phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis

scientific article published in October 2009

Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

scientific article

Structural changes of TasA in biofilm formation of Bacillus subtilis.

scientific article published on 12 March 2018

Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work

scientific article

SuperSweet--a resource on natural and artificial sweetening agents

scientific article

The Translational Landscape of the Human Heart

scientific article published on 30 May 2019

List of works by Catherine Louise Worth

A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease.

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity

An interactive web-tool for molecular analyses links naturally occurring mutation data with three-dimensional structures of the rhodopsin-like glycoprotein hormone receptors

Binding sites in membrane proteins--diversity, druggability and prospects

Cells and gene expression programs in the adult human heart

Cells of the adult human heart

Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models

Development of immune-specific interaction potentials and their application in the multi-agent-system VaccImm

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

Family 18 chitinase–oligosaccharide substrate interaction: subsite preference and anomer selectivity of Serratia marcescens chitinase A

FragmentStore--a comprehensive database of fragments linking metabolites, toxic molecules and drugs

From molecular details of the interplay between transmembrane helices of the thyrotropin receptor to general aspects of signal transduction in family a G-protein-coupled receptors (GPCRs).

GPCR-SSFE 2.0-a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.

GPCR-SSFE: a comprehensive database of G-protein-coupled receptor template predictions and homology models

Genome bioinformatic analysis of nonsynonymous SNPs

Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options

Meet me halfway: when genomics meets structural bioinformatics

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors.

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture

PDBLIG: classification of small molecular protein binding in the Protein Data Bank

Principles and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.

Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Research resource: Update and extension of a glycoprotein hormone receptors web application

Residues of a proposed gate region in type I ATP-binding cassette import systems are crucial for function as revealed by mutational analysis

SDM--a server for predicting effects of mutations on protein stability and malfunction ⬇️

Satisfaction of hydrogen-bonding potential influences the conservation of polar sidechains.

Signaling-sensitive amino acids surround the allosteric ligand binding site of the thyrotropin receptor

Structural and functional constraints in the evolution of protein families

Structural and functional restraints in the evolution of protein families and superfamilies.

Structural bioinformatics mutation analysis reveals genotype-phenotype correlations in von Hippel-Lindau disease and suggests molecular mechanisms of tumorigenesis

Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery

Structural changes of TasA in biofilm formation of Bacillus subtilis.

Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work

SuperSweet--a resource on natural and artificial sweetening agents

The Translational Landscape of the Human Heart