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List of works by Irina Isakova-Sivak

A Phase 1 Randomized Placebo-Controlled Study to Assess the Safety, Immunogenicity and Genetic Stability of a New Potential Pandemic H7N9 Live Attenuated Influenza Vaccine in Healthy Adults

scientific article published on 10 June 2020

Analysis of Immune Epitopes of Respiratory Syncytial Virus for Designing of Vectored Vaccines Based on Influenza Virus Platform.

scientific article published on 3 September 2016

Assessment of human immune responses to H7 avian influenza virus of pandemic potential: results from a placebo-controlled, randomized double-blind phase I study of live attenuated H7N3 influenza vaccine.

scientific article

Assessment of immune responses to H5N1 inactivated influenza vaccine among individuals previously primed with H5N2 live attenuated influenza vaccine.

scientific article

Basics of CD8 T-cell immune responses after influenza infection and vaccination with inactivated or live attenuated influenza vaccine

article

Broadly protective anti-hemagglutinin stalk antibodies induced by live attenuated influenza vaccine expressing chimeric hemagglutinin.

scientific article published on 22 March 2018

Characterization of reverse genetics-derived cold-adapted master donor virus A/Leningrad/134/17/57 (H2N2) and reassortants with H5N1 surface genes in a mouse model.

scientific article

Cold-adapted influenza viruses as a promising platform for viral-vector vaccines.

scientific article published on 6 July 2016

Comparative immunogenicity and cross-clade protective efficacy of mammalian cell-grown inactivated and live attenuated H5N1 reassortant vaccines in ferrets

scientific article

Comparative studies of infectivity, immunogenicity and cross-protective efficacy of live attenuated influenza vaccines containing nucleoprotein from cold-adapted or wild-type influenza virus in a mouse model

scientific article

Contribution of neuraminidase of influenza viruses to the sensitivity to sera inhibitors and reassortment efficiency

scientific article published on 11 July 2014

Cross-protection against H7N9 influenza strains using a live-attenuated H7N3 virus vaccine

scientific article published on 18 November 2014

Development and approval of live attenuated influenza vaccines based on Russian master donor viruses: Process challenges and success stories.

scientific article

Development and pre-clinical evaluation of two LAIV strains against potentially pandemic H2N2 influenza virus.

scientific article

Genetic bases of the temperature-sensitive phenotype of a master donor virus used in live attenuated influenza vaccines: A/Leningrad/134/17/57 (H2N2).

scientific article published on 18 February 2011

Genetic stability of live attenuated vaccines against potentially pandemic influenza viruses.

scientific article

Genotyping assay for differentiation of wild-type and vaccine viruses in subjects immunized with live attenuated influenza vaccine

scientific article published on 7 July 2017

H2N2 live attenuated influenza vaccine is safe and immunogenic for healthy adult volunteers.

scientific article

H7N3 live attenuated influenza vaccine has a potential to protect against new H7N9 avian influenza virus

scientific article published on 26 August 2013

H7N9 Live Attenuated Influenza Vaccine Is Highly Immunogenic, Prevents Virus Replication, and Protects Against Severe Bronchopneumonia in Ferrets

scientific article

H7N9 live attenuated influenza vaccine in healthy adults: a randomised, double-blind, placebo-controlled, phase 1 trial.

scientific article

H7N9: can H7N3 live-attenuated influenza vaccine be used at the early stage of the pandemic?

scientific article published on 28 November 2013

Immunogenicity and Cross Protection in Mice Afforded by Pandemic H1N1 Live Attenuated Influenza Vaccine Containing Wild-Type Nucleoprotein.

scientific article

Insights into current clinical research on the immunogenicity of live attenuated influenza vaccines

scientific article published on 18 January 2020

Live Attenuated Influenza Vaccines engineered to express the nucleoprotein of a recent isolate stimulate human influenza CD8+ T cells more relevant to current infections

scientific article published on 18 December 2017

Live attenuated influenza vaccine viral vector induces functional cytotoxic T-cell immune response against foreign CD8+ T-cell epitopes inserted into NA and NS1 genes using the 2A self-cleavage site

article

M2e-based universal influenza vaccines: a historical overview and new approaches to development

scientific article published on 19 October 2019

Overview of human rhinovirus immunogenic epitopes for rational vaccine design

scientific article published on 21 August 2019

Pandemic preparedness with live attenuated influenza vaccines based on A/Leningrad/134/17/57 master donor virus

scientific article

Reassortant viruses for influenza vaccines: is it time to reconsider their genome structures?

scientific article published on 27 February 2016

Recombinant Live Attenuated Influenza Vaccine Viruses Carrying Conserved T-cell Epitopes of Human Adenoviruses Induce Functional Cytotoxic T-Cell Responses and Protect Mice against Both Infections

scientific article published on 24 April 2020

Recombinant live attenuated influenza vaccine viruses carrying CD8 T-cell epitopes of respiratory syncytial virus protect mice against both pathogens without inflammatory disease

scientific article published on 07 May 2019

Safety, immunogenicity and infectivity of new live attenuated influenza vaccines.

scientific article

Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge

scientific article published on 08 July 2019

Tackling a novel lethal virus: a focus on H7N9 vaccine development.

scientific article

The development of vaccine viruses against pandemic A(H1N1) influenza ⬇️

scientific article published on February 17, 2011

Two Live Attenuated Vaccines against Recent Low⁻and Highly Pathogenic H7N9 Influenza Viruses Are Safe and Immunogenic in Ferrets

scientific article published on 01 November 2018

Use of live attenuated influenza vaccines in young children in resource-poor settings

scientific article published on 13 October 2016

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