List of works - James David West

A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis

scientific article published on 01 January 2020

A potential role for insulin resistance in experimental pulmonary hypertension

scientific article published on 30 August 2012

Adenoviral gene transfer to the neonatal rat pulmonary circulation.

scientific article

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

scientific article published on 24 May 2019

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

scientific article published on 08 April 2009

Are Obliterative Pulmonary Vascular Lesions Reversible? ⬇️

scientific article published on August 15, 2011

CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema

scientific article published on 18 May 2012

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

scientific article

Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension

scientific article published on 16 June 2009

Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension

scientific article published on January 2010

Effective treatments for PAH will require detailed knowledge of molecular aetiology.

scientific article

Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development

scientific journal article

Experimental and transgenic models of pulmonary hypertension.

scientific article published on April 2011

Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

scientific article

Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene

scientific article

Genome Editing in Large Animals.

scientific article published on 25 March 2016

In Defense of Merit in Science

scientific article published on 28 April 2023

Inhalation of Stachybotrys chartarum evokes pulmonary arterial remodeling in mice, attenuated by Rho-kinase inhibitor.

scientific article

Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension.

scientific article

Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension

scientific article

Microarray studies in pulmonary arterial hypertension ⬇️

scientific article published on January 1, 2011

Murine pulmonary response to chronic hypoxia is strain specific.

scientific article published on August 2008

Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension

scientific article published on 01 October 2019

Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.

scientific article

Physiologic and molecular consequences of endothelial Bmpr2 mutation

scientific article

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

scientific article published on 18 March 2004

Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

scientific article published on 19 August 2011

Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.

scientific article

The Pathology of Bleomycin-Induced Fibrosis Is Associated with Loss of Resident Lung Mesenchymal Stem Cells That Regulate Effector T-cell Proliferation ⬇️

scientific article published on April 1, 2011

The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched- related gene, TRC8 ⬇️

scientific article published on August 4, 1998

Unrecognized glucose intolerance is common in pulmonary arterial hypertension

scientific article

Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension

scientific article

List of works by James David West

A multifaceted investigation into molecular associations of chronic thromboembolic pulmonary hypertension pathogenesis

A potential role for insulin resistance in experimental pulmonary hypertension

Adenoviral gene transfer to the neonatal rat pulmonary circulation.

Adverse effects of BMPR2 suppression in macrophages in animal models of pulmonary hypertension

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

Are Obliterative Pulmonary Vascular Lesions Reversible? ⬇️

CD40 amplifies Fas-mediated apoptosis: a mechanism contributing to emphysema

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

Copy-number variation in BMPR2 is not associated with the pathogenesis of pulmonary arterial hypertension

Cross talk between Smad, MAPK, and actin in the etiology of pulmonary arterial hypertension

Effective treatments for PAH will require detailed knowledge of molecular aetiology.

Embryonic growth-associated protein is one subunit of a novel N-terminal acetyltransferase complex essential for embryonic vascular development

Experimental and transgenic models of pulmonary hypertension.

Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

Gene expression in lungs of mice lacking the 5-hydroxytryptamine transporter gene

Genome Editing in Large Animals.

In Defense of Merit in Science

Inhalation of Stachybotrys chartarum evokes pulmonary arterial remodeling in mice, attenuated by Rho-kinase inhibitor.

Longitudinal analysis casts doubt on the presence of genetic anticipation in heritable pulmonary arterial hypertension.

Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension

Microarray studies in pulmonary arterial hypertension ⬇️

Murine pulmonary response to chronic hypoxia is strain specific.

Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension

Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.

Physiologic and molecular consequences of endothelial Bmpr2 mutation

Pulmonary hypertension in transgenic mice expressing a dominant-negative BMPRII gene in smooth muscle

Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

Role of BMPR2 alternative splicing in heritable pulmonary arterial hypertension penetrance.

The Pathology of Bleomycin-Induced Fibrosis Is Associated with Loss of Resident Lung Mesenchymal Stem Cells That Regulate Effector T-cell Proliferation ⬇️

The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched- related gene, TRC8 ⬇️

Unrecognized glucose intolerance is common in pulmonary arterial hypertension

Whole exome sequencing to identify a novel gene (caveolin-1) associated with human pulmonary arterial hypertension