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List of works by Alessia Finotti

A Distinctive microRNA (miRNA) Signature in the Blood of Colorectal Cancer (CRC) Patients at Surgery

scientific article published on 25 August 2020

A Novel Frameshift Mutation (+A) at Codon 18 of the β-Globin Gene Associated with High Persistence of Fetal Hemoglobin Phenotype and δβ-Thalassemia

article

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3'UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

scientific article published on 05 April 2020

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells

scientific article

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs

scientific article published on 23 June 2022

A validated cellular biobank for β-thalassemia

scientific article published on 02 September 2016

Altered erythroid-related miRNA levels as a possible novel biomarker for detection of autologous blood transfusion misuse in sport

scientific article published on 30 May 2019

An Aγ-globin G->A gene polymorphism associated with β039 thalassemia globin gene and high fetal hemoglobin production

scientific article published on 29 August 2017

An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system.

scientific article published on 3 February 2017

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

scientific article published on 26 November 2017

Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA.

scientific article published in February 2004

Changes in hemoglobin profile reflect autologous blood transfusion misuse in sports.

scientific article published on 23 March 2018

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae

scientific article

Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy Activity

Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line

scientific article

Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin

scientific article published on 2 September 2015

Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters

scientific article published on 04 July 2019

Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations

scientific article published on 9 July 2009

Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

scientific article published on 27 September 2017

Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene

scientific article

Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.

scientific article

Efficient CRISPR-Cas9-based genome editing of β-globin gene on erythroid cells from homozygous β<sup>0</sup>39-thalassemia patients

scientific article published on 03 April 2021

Efficient cell penetration and delivery of peptide nucleic acids by an argininocalix[4]arene

scientific article published on 28 February 2019

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p

scientific article published on 01 June 2019

Epigenetic changes as a common trigger of muscle weakness in congenital myopathies

scientific article

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions

scientific article published on 03 December 2014

Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses.

scientific article published on June 2014

Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.

scientific article published on 4 May 2015

High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222.

scientific article published on 24 December 2015

Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs

scientific article published on 25 September 2009

Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells

scientific article

Involvement of miRNA in erythroid differentiation

scientific article published on February 2012

In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells

scientific article

Isothermal circular-strand-displacement polymerization of DNA and microRNA in digital microfluidic devices

scientific article published on 13 January 2015

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

scientific article published on 06 August 2018

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA).

scientific article published on 26 June 2018

Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells.

scientific article

MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells

scientific article published on 15 March 2016

MicroRNAs and Long Non-coding RNAs in Genetic Diseases

scientific article published on 01 April 2019

Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs).

scientific article

Molecular methods for validation of the biological activity of peptide nucleic acids targeting microRNAs

scientific article published on January 2014

Multiple levels of control of the expression of the human A beta H-J-J locus encoding aspartyl-beta-hydroxylase, junctin, and junctate

scientific article published on December 2006

Myocyte enhancer factor 2 activates promoter sequences of the human AbetaH-J-J locus, encoding aspartyl-beta-hydroxylase, junctin, and junctate

scientific article

New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes.

scientific article published on 23 September 2016

Non-invasive Prenatal Testing Using Fetal DNA

scientific article published on 01 April 2019

Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations

PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis.

scientific article published on 4 December 2017

Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells

scientific article

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells

scientific article

Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 thalassemia patients

scientific article published on November 2009

Psoralen derivatives as inhibitors of NF-κB/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation

scientific article published on 25 February 2013

Real-time multiplex analysis of four beta-thalassemia mutations employing surface plasmon resonance and biosensor technology

scientific article published in June 2004

Recent patents and technology transfer for molecular diagnosis of β-thalassemia and other hemoglobinopathies

scientific article published on 28 September 2015

Recent trends for novel options in experimental biological therapy of β-thalassemia

scientific article

Recent trends in the gene therapy of β-thalassemia

scientific article

Regulation of IL-8 gene expression in gliomas by microRNA miR-93.

scientific article published on 8 October 2015

Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients

scientific article

Structural and Functional Insights on an Uncharacterized Aγ-Globin-Gene Polymorphism Present in Four β0-Thalassemia Families with High Fetal Hemoglobin Levels.

scientific article

Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor

scientific article published on 7 December 2008

Surface plasmon resonance based analysis of the binding of LYAR protein to the rs368698783 (G>A) polymorphic Aγ-globin gene sequences mutated in β-thalassemia

scientific article published on 12 July 2019

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold

scientific article published on 07 April 2020

Targeting DNA Binding for NF-κB as an Anticancer Approach in Hepatocellular Carcinoma

scientific article published on 22 October 2018

Targeting miR‑155‑5p and miR‑221‑3p by peptide nucleic acids induces caspase‑3 activation and apoptosis in temozolomide‑resistant T98G glioma cells.

scientific article published on 23 May 2019

Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development

scientific article published on 16 August 2011

Tobramycin is a suppressor of premature termination codons

scientific article

Transcriptional activity and Sp 1/3 transcription factor binding to the P1 promoter sequences of the human AbetaH-J-J locus

scientific article published on 06 August 2007

Transient Receptor Potential Ankyrin 1 Channels Modulate Inflammatory Response in Respiratory Cells from Patients with Cystic Fibrosis.

scientific article

Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.

scientific article published on 10 December 2010

UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation.

scientific article published on 15 May 2018

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the A beta H-J-J locus

scientific article

Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221.

scientific article published on 5 March 2014

Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance

scientific article

miRNA array screening reveals cooperative MGMT-regulation between miR-181d-5p and miR-409-3p in glioblastoma

scientific article published on 05 April 2016

miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs

scientific article published on December 2011

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